Phenotype: abnormal startle reflex

Definition
aberrant threshold or reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal startle reflex

Total number of significant genotype-phenotype associations: 679

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
0.00
Mboat1
Mboat1em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.16×10-37
Aldh3a2
Aldh3a2tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.77×10-29
Pacs2
Pacs2tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.96×10-28
Fbxo11
Fbxo11Jf
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.55×10-27
Palm3
Palm3tm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.36×10-24
Kcne1
Kcne1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
1.24×10-21
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
7.54×10-21
Clk2
Clk2em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.07×10-20
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.53×10-20
Slc8a3
Slc8a3tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.66×10-20
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
1.98×10-19
Usp53
Usp53em1(IMPC)Tcp
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
TCP
IMPC
3.53×10-19
Slc17a8
Slc17a8em1(IMPC)Mbp
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
6.86×10-19
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
7.28×10-19
Rtn4
Rtn4em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.01×10-18
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.63×10-18
Atf7
Atf7tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.90×10-18
Atxn7
Atxn7em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
3.08×10-18
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.15×10-17
Zfp13
Zfp13tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.35×10-17
Phldb2
Phldb2em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.48×10-17
Cldn9
Cldn9em1(IMPC)H
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.03×10-17
Marveld2
Marveld2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
6.55×10-17
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
6.55×10-17
Rell1
Rell1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.59×10-17
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
1.05×10-16
Prkd2
Prkd2em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.60×10-16
Fgf20
Fgf20em1(IMPC)Ccpcz
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
CCP-IMG
IMPC
2.07×10-16
Clrn1
Clrn1tm1.1(KOMP)Vlcg
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
2.10×10-16
Myo6
Myo6em1(IMPC)Tcp
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
TCP
IMPC
3.98×10-16
Etl4
Etl4em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
5.11×10-16
Ssbp2
Ssbp2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.62×10-16
Baiap2l2
Baiap2l2tm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
1.24×10-15
Lat
Latem1(IMPC)Ics
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
1.24×10-15
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.13×10-15
Mecom
MecomJbo
HET Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.55×10-15
Kcne1
Kcne1tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.33×10-15
Abcb4
Abcb4tm1Bor
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
7.15×10-15
Tmtc4
Tmtc4tm1.1(KOMP)Vlcg
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
7.73×10-15
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
1.19×10-14
Limk2
Limk2tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.52×10-14
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.02×10-14
Mx2
Mx2em1(IMPC)Ics
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
7.00×10-14
Setdb1
Setdb1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.28×10-13
Slc17a8
Slc17a8em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.49×10-13
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
HMGU
IMPC
1.99×10-13
Trpc3
Trpc3Mwk
HET Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.45×10-13
Sun1
Sun1tm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
3.28×10-13
Syncrip
Syncriptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.32×10-13
Tox
Toxtm1b(KOMP)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
5.73×10-13
Cops4
Cops4tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.83×10-13
Nedd4l
Nedd4ltm1b(KOMP)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.84×10-13
Hif1an
Hif1anem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.20×10-12
Yipf1
Yipf1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
MGP
1.28×10-12
Trp53
Trp53tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.39×10-12
Notch1
Notch1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.75×10-12
Cdk13
Cdk13tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.18×10-12
Nhs
Nhsem1(IMPC)Tcp
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.44×10-12
Ephx1
Ephx1Ephx1
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.20×10-12
Fbxo11
Fbxo11Jf
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
6.68×10-12
Grin2b
Grin2btm1e.1(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.12×10-12
Thra
Thratm1b(EUCOMM)Wtsi
HET Late adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.07×10-11
Ncor2
Ncor2Ncor2
HOM Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.32×10-11
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
1.49×10-11
Tomm40
Tomm40em1(IMPC)J
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
1.55×10-11
Fgf7
Fgf7tm1e.1(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
1.61×10-11
Kpna4
Kpna4em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.85×10-11
Zfp69
Zfp69tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.26×10-11
Zfp462
Zfp462em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.49×10-11
Vat1l
Vat1ltm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.13×10-10
Clk1
Clk1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.25×10-10
Secisbp2l
Secisbp2lem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.58×10-10
Ppargc1a
Ppargc1aem1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.71×10-10
Rab5a
Rab5atm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.19×10-10
Nhs
Nhsem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.26×10-10
Becn1
Becn1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.58×10-10
Mob2
Mob2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
4.74×10-10
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
TCP
IMPC
5.02×10-10
Mtarc2
Mtarc2tm2a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.35×10-10
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.17×10-10
Klhdc7b
Klhdc7bem1(IMPC)H
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
7.68×10-10
Peak1
Peak1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.96×10-10
Lmod3
Lmod3em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.17×10-10
Otoa
Otoatm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.54×10-10
Gins4
Gins4tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
9.18×10-10
Pkn2
Pkn2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.18×10-09
Lrrc41
Lrrc41em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.49×10-09
Neurod2
Neurod2em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.54×10-09
F2rl1
F2rl1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.78×10-09
Dgkk
Dgkkem1(IMPC)Ics
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
2.16×10-09
Strbp
Strbpem1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.23×10-09
Sox13
Sox13tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.53×10-09
Eps8l2
Eps8l2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
2.66×10-09
Tardbp
Tardbptm1b(EUCOMM)Wtsi
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
3.17×10-09
Ctnnb1
Ctnnb1Bfc
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
3.60×10-09
Mat2a
Mat2atm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.62×10-09
Rprd1b
Rprd1btm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.49×10-09
Prkcsh
Prkcshtm1.1(KOMP)Vlcg
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
4.58×10-09
Kcnj10
Kcnj10tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
4.76×10-09
Nin
Nintm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
RBRC
IMPC
4.91×10-09
Prpsap2
Prpsap2tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.03×10-09
Klhdc7b
Klhdc7bem1(IMPC)H
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.77×10-09
Fam83d
Fam83dem1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
6.29×10-09
Nol8
Nol8tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.46×10-09
Herpud2
Herpud2tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.77×10-09
Abcc5
Abcc5em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
6.78×10-09
Rab11fip3
Rab11fip3em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.82×10-09
Thra
Thratm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.04×10-09
Cacnb4
Cacnb4tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
7.57×10-09
Il20
Il20em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.08×10-09
Cct3
Cct3em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.17×10-09
Nfya
NfyaGt(EUCJ0004f10)Hmgu
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
HMGU
EuroPhenome
1.03×10-08
Nipsnap1
Nipsnap1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.03×10-08
Adgrv1
Adgrv1tm1.1(KOMP)Vlcg
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
1.07×10-08
Bex2
Bex2tm1b(EUCOMM)Hmgu
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.27×10-08
Cacna2d1
Cacna2d1em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.38×10-08
Baiap2l2
Baiap2l2tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.47×10-08
Zfp715
Zfp715tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.52×10-08
Nsd3
Nsd3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.60×10-08
Susd6
Susd6tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.79×10-08
Cabp2
Cabp2em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.16×10-08
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.35×10-08
Ubr7
Ubr7em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.48×10-08
Ctnnb1
Ctnnb1Bfc
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.51×10-08
Zdhhc5
Zdhhc5tm1e.1(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.61×10-08
Rab11fip3
Rab11fip3em1(IMPC)J
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
2.73×10-08
Ust
Ustem1(IMPC)J
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
2.73×10-08
Wbp2
Wbp2tm2a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.97×10-08
Dym
Dymem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.06×10-08
Ube2h
Ube2htm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
3.55×10-08
Atp1b1
Atp1b1em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.00×10-08
Colec12
Colec12em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.07×10-08
Cgas
Cgastm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.09×10-08
Shh
Shhtm1Chg
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.41×10-08
Iqgap2
Iqgap2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.44×10-08
Hint1
Hint1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.75×10-08
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
TCP
IMPC
4.90×10-08
Vdac1
Vdac1tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.10×10-08
Fam43a
Fam43aem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.86×10-08
C1qtnf1
C1qtnf1em1(IMPC)Mbp
HOM   Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
5.95×10-08
Pcm1
Pcm1em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.09×10-08
Arvcf
Arvcftm1e(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
6.46×10-08
Rpe65
Rpe65tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
6.52×10-08
Farp1
Farp1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.68×10-08
Hipk3
Hipk3tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.29×10-08
Fgf9
Fgf9tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.57×10-08
Armt1
Armt1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
8.60×10-08
Baiap2l2
Baiap2l2tm1a(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
8.69×10-08
Cldn11
Cldn11em1(IMPC)H
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
9.11×10-08
Bfsp1
Bfsp1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
9.69×10-08
Ncoa7
Ncoa7tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.01×10-07
Spg11
Spg11em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.02×10-07
Zmym2
Zmym2em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.02×10-07
Ccnt1
Ccnt1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.08×10-07
Ptpra
Ptpratm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.14×10-07
Kif13a
Kif13aem1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.19×10-07
Palm3
Palm3tm1b(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
HMGU
IMPC
1.20×10-07
Mir96
Mir96Dmdo
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
WTSI
MGP
1.27×10-07
Rab5b
Rab5bem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.29×10-07
Enpep
Enpeptm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.29×10-07
Scamp2
Scamp2em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.35×10-07
Rps26
Rps26tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.38×10-07
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.45×10-07
Sgsh
Sgshem3(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.45×10-07
Cpe
Cpetm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.52×10-07
Rnf187
Rnf187em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.63×10-07
Sorl1
Sorl1tm1a(EUCOMM)Wtsi
HOM Late adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.72×10-07
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Late adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.74×10-07
Rgl1
Rgl1em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.22×10-07
Hhatl
Hhatlem1(IMPC)Mbp
HOM   Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
2.29×10-07
Eps8l2
Eps8l2tm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.30×10-07
Sarnp
Sarnptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.51×10-07
Fpgs
Fpgstm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.97×10-07
Septin8
Septin8tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.07×10-07
Itgb1
Itgb1em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
3.15×10-07
Clrn2
Clrn2em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.17×10-07
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
3.25×10-07
0610010K14Rik
0610010K14Riktm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.29×10-07
Pcyox1l
Pcyox1lem1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.55×10-07
Gar1
Gar1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.59×10-07
Mybbp1a
Mybbp1atm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.60×10-07
Mecom
MecomJbo
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
3.60×10-07
Tram1
Tram1em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.62×10-07
Prkg1
Prkg1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.69×10-07
Slc4a10
Slc4a10tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.74×10-07
Plscr5
Plscr5em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.76×10-07
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
4.07×10-07
Myc
Mycem1(IMPC)Kmpc
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
4.12×10-07
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.13×10-07
Capn5
Capn5tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.24×10-07
Tpm1
Tpm1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 startle magnitude
Acoustic Startle&PPI
WTSI
EuroPhenome
4.53×10-07
Gsta3
Gsta3tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.67×10-07
Ubn1
Ubn1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.87×10-07
Mir96
Mir96Dmdo
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
WTSI
MGP
4.91×10-07
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.04×10-07
Atp8a1
Atp8a1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
5.08×10-07
Aak1
Aak1tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
5.19×10-07
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
5.39×10-07
Chrna9
Chrna9tm2a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
5.41×10-07
Relch
Relchem1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.13×10-07
Cant1
Cant1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.34×10-07
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
6.70×10-07
Gnas
Gnastm1Jop
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
6.97×10-07
Ficd
Ficdtm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
6.97×10-07
Zfp629
Zfp629em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.98×10-07
Cdc37
Cdc37em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.08×10-07
Ppy
Ppytm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.26×10-07
Eif2s1
Eif2s1em1(IMPC)Mbp
HET   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.68×10-07
Stim2
Stim2tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.61×10-07
Brpf1
Brpf1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
8.68×10-07
Gmeb2
Gmeb2em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.75×10-07
Grxcr1
Grxcr1em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.96×10-07
Mon1a
Mon1aem1(IMPC)J
HOM   Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.01×10-07
Ttc17
Ttc17em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.37×10-07
Ylpm1
Ylpm1tm1b(KOMP)Wtsi
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.88×10-07
Marveld2
Marveld2tm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.01×10-06
Wtap
Wtaptm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.03×10-06
Cast
Casttm1.1(KOMP)Vlcg
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.03×10-06
H6pd
H6pdtm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.06×10-06
Aspa
Aspatm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.10×10-06
Senp7
Senp7tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
1.13×10-06
Zfp91
Zfp91em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.17×10-06
H2az1
H2az1em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.18×10-06
Mtmr3
Mtmr3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.20×10-06
Gnasas1
Gnasas1tm1Jop
HET   Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
1.23×10-06
Msi2
Msi2em1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.26×10-06
Tdrkh
Tdrkhtm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.27×10-06
Crtc1
Crtc1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.29×10-06
Pmel
Pmeltm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.32×10-06
Gm12258
Gm12258tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.38×10-06
Cep85l
Cep85lem1(IMPC)Mbp
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
1.40×10-06
Ajap1
Ajap1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.42×10-06
Slc44a2
Slc44a2em1(IMPC)J
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
1.48×10-06
Hgsnat
Hgsnatem4(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.55×10-06
Fkbp1b
Fkbp1btm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.58×10-06
Sema5b
Sema5btm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.58×10-06
Krtap8-1
Krtap8-1em1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
1.61×10-06
Spryd3
Spryd3tm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.63×10-06
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.71×10-06
Cd84
Cd84tm1b(KOMP)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.71×10-06
E2f3
E2f3tm1b(KOMP)Wtsi
HET   Late adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.76×10-06
Cxcl5
Cxcl5em1(IMPC)Kmpc
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.77×10-06
Itk
Itkem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.90×10-06
Zmym2
Zmym2em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.05×10-06
Vopp1
Vopp1em1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
2.05×10-06
Ngfr
Ngfrtm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.10×10-06
Lnpk
Lnpkem1(IMPC)Bay
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.13×10-06
C2cd2l
C2cd2lem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.15×10-06
Fam81a
Fam81aem1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
2.25×10-06
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.26×10-06
Gde1
Gde1tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.26×10-06
Sox14
Sox14em1(IMPC)Ccpcz
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
2.27×10-06
Pou2af3
Pou2af3tm1b(NCOM)Mfgc
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.30×10-06
H3f3b
H3f3btm1.1(KOMP)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.34×10-06
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM   Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
2.36×10-06
Frmd5
Frmd5tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
2.38×10-06
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.39×10-06
Il1a
Il1atm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.52×10-06
Tpo
Tpoem1(IMPC)H
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
2.55×10-06
Nt5c2
Nt5c2em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.69×10-06
Proser2
Proser2em1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
2.97×10-06
Slc4a8
Slc4a8em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.01×10-06
Grxcr1
Grxcr1em1(IMPC)J
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
3.01×10-06
Hacd3
Hacd3em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.08×10-06
Adprm
Adprmtm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.13×10-06
Klhdc7b
Klhdc7bem1(IMPC)H
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.28×10-06
Oplah
Oplahtm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.28×10-06
Tmem116
Tmem116tm1b(EUCOMM)Hmgu
HOM Late adult abnormal startle reflex Startle response
SHIRPA
HMGU
IMPC
3.28×10-06
Dis3
Dis3tm1e.1(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.32×10-06
Phykpl
Phykpltm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.33×10-06
Exoc3l
Exoc3lem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.39×10-06
Slc9a4
Slc9a4tm1b(EUCOMM)Wtsi
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.41×10-06
Dach1
Dach1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.44×10-06
Chrm4
Chrm4tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.52×10-06
Apobec1
Apobec1em1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
3.55×10-06
Llgl2
Llgl2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.80×10-06
Mtmr2
Mtmr2em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.92×10-06
Ilrun
IlrunGt(IST12471H5)Tigm
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.01×10-06
Sox21
Sox21em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.03×10-06
Cdin1
Cdin1em1(IMPC)J
HET Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
4.12×10-06
Wdr45
Wdr45em1(IMPC)J
HEM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
4.12×10-06
Lhx1
Lhx1tm1e(EUCOMM)Wtsi
HET   Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.15×10-06
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
4.43×10-06
Bahd1
Bahd1tm2b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
4.46×10-06
Grhl3
Grhl3tm1a(EUCOMM)Wtsi
HET   Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.48×10-06
Gramd1c
Gramd1ctm1b(KOMP)Wtsi
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.48×10-06
Moxd1
Moxd1tm2b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.56×10-06
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.60×10-06
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.63×10-06
Abhd15
Abhd15tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
4.68×10-06
Acbd3
Acbd3tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.69×10-06
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM   Early adult abnormal startle reflex Startle response
Modified SHIRPA
WTSI
EuroPhenome
4.75×10-06
Plekha5
Plekha5em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.90×10-06
Mcidas
Mcidasem2(IMPC)Tcp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
5.12×10-06
Igf2bp3
Igf2bp3em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.22×10-06
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
5.27×10-06
Mag
Magtm1.1(KOMP)Vlcg
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.35×10-06
Ascc3
Ascc3tm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.49×10-06
Calcoco1
Calcoco1em1(IMPC)H
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.61×10-06
Myo1d
Myo1dem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.69×10-06
Epb41l1
Epb41l1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.80×10-06
Bltp1
Bltp1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.81×10-06
Ifit3
Ifit3em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.25×10-06
Col11a2
Col11a2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.25×10-06
Mtmr14
Mtmr14tm1a(KOMP)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.77×10-06
Iffo2
Iffo2em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.80×10-06
Mfng
Mfngem1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
7.06×10-06
Nufip2
Nufip2em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.10×10-06
Usp53
Usp53em1(IMPC)Tcp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
7.11×10-06
Plag1
Plag1em1(IMPC)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.21×10-06
Sprr1a
Sprr1aem1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
7.23×10-06
Sirt6
Sirt6tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.63×10-06
Parl
Parltm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.80×10-06
Usp31
Usp31em1(IMPC)H
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
7.83×10-06
Ryr2
Ryr2tm1b(KOMP)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
7.84×10-06
Dnajb11
Dnajb11tm1b(EUCOMM)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.11×10-06
Dusp7
Dusp7tm1(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
8.12×10-06
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
8.13×10-06
Cdc123
Cdc123tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.50×10-06
Grhl2
Grhl2em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.56×10-06
Otogl
Otoglem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.57×10-06
Brix1
Brix1tm1b(KOMP)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
8.59×10-06
Rnaseh2a
Rnaseh2aem1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.07×10-06
Nr1h4
Nr1h4Nr1h4
HOM   Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
9.30×10-06
Zbtb5
Zbtb5tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
9.40×10-06
Gna11
Gna11tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
9.54×10-06
Ubl7
Ubl7em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.60×10-06
Gramd1c
Gramd1ctm1b(KOMP)Wtsi
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.97×10-06
Irgm2
Irgm2em1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.97×10-06
Mcf2l
Mcf2ltm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.01×10-05
Mpdz
Mpdzem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.01×10-05
Pum2
Pum2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.01×10-05
Muc5b
Muc5bem1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.06×10-05
Rps6ka1
Rps6ka1em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.09×10-05
Epg5
Epg5em1(IMPC)H
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.12×10-05
Brms1
Brms1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.14×10-05
Prrt2
Prrt2tm1b(KOMP)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.15×10-05
Myo6
Myo6em1(IMPC)Tcp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.15×10-05
Zfp119a
Zfp119atm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.19×10-05
Kcnj12
Kcnj12tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.19×10-05
Ctsa
Ctsatm2b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.20×10-05
Tars3
Tars3em1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.21×10-05
Tbc1d9b
Tbc1d9bem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.21×10-05
Uchl1
Uchl1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.24×10-05
Tmem145
Tmem145em1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.26×10-05
Gm5134
Gm5134tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.26×10-05
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.29×10-05
Rnf10
Rnf10em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.33×10-05
Tiprl
Tiprltm1.1(KOMP)Vlcg
HET   Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
1.33×10-05
Atp6v0d1
Atp6v0d1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.38×10-05
Mettl23
Mettl23em1(IMPC)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.39×10-05
Tnks2
Tnks2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.41×10-05
Mipep
Mipepem1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.43×10-05
Ddx52
Ddx52tm1a(EUCOMM)Wtsi
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.44×10-05
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.44×10-05
Chst2
Chst2em1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.48×10-05
Btbd2
Btbd2em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.50×10-05
Rbfox3
Rbfox3tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.53×10-05
Dock4
Dock4em1(IMPC)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
HMGU
IMPC
1.53×10-05
Letmd1
Letmd1em1(IMPC)Kmpc
HOM   Late adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.55×10-05
Bmp6
Bmp6em1(IMPC)Ccpcz
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
1.56×10-05
Tmie
Tmieem1(IMPC)J
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
1.58×10-05
Krtcap2
Krtcap2em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.60×10-05
Rfxank
Rfxanktm1b(EUCOMM)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.60×10-05
Sun1
Sun1tm1b(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
ICS
IMPC
1.66×10-05
Clcn1
Clcn1em1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.69×10-05
Strbp
Strbpem1(IMPC)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
HMGU
IMPC
1.71×10-05
Golga5
Golga5tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.71×10-05
Bex2
Bex2tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.74×10-05
Tmtc4
Tmtc4tm1.1(KOMP)Vlcg
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.74×10-05
Cdkn2aip
Cdkn2aipem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.75×10-05
Rcc1l
Rcc1ltm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.79×10-05
Cox20
Cox20em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.83×10-05
Cep85l
Cep85lem1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.84×10-05
Tm2d2
Tm2d2em1(IMPC)Bay
HET Late adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.84×10-05
Lmod3
Lmod3em1(IMPC)Mbp
HOM   Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
1.85×10-05
Rbm22
Rbm22tm1.1(KOMP)Vlcg
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.86×10-05
Garin1a
Garin1aem1(IMPC)Ccpcz
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
1.89×10-05
Tmem72
Tmem72tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.91×10-05
Drg2
Drg2tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.92×10-05
Smg6
Smg6em1(IMPC)Mbp
HET Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
1.94×10-05
Zbtb12
Zbtb12em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.94×10-05
Phlpp2
Phlpp2em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.98×10-05
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.98×10-05
Bicd1
Bicd1tm1.1(KOMP)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.99×10-05
Fbxo30
Fbxo30tm1b(KOMP)Wtsi
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.06×10-05
Foxo3
Foxo3tm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.13×10-05
Sufu
Sufutm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.13×10-05
Lama1
Lama1tm2b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.19×10-05
Ypel3
Ypel3tm1.1(KOMP)Vlcg
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
2.20×10-05
Bcl2l15
Bcl2l15tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.21×10-05
Akr7a5
Akr7a5tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.21×10-05
Pspc1
Pspc1em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.22×10-05
Gipc3
Gipc3tm1b(KOMP)Wtsi
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.24×10-05
B9d1
B9d1tm1a(EUCOMM)Wtsi
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
ICS
EuroPhenome
2.27×10-05
Slc5a5
Slc5a5tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.29×10-05
Nr3c2
Nr3c2Nr3c2
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.31×10-05
Septin8
Septin8tm1a(EUCOMM)Wtsi
HOM   Early adult abnormal startle reflex Startle response
Modified SHIRPA
ICS
EuroPhenome
2.35×10-05
Lclat1
Lclat1em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.37×10-05
Cartpt
Cartptem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.37×10-05
Fbxo2
Fbxo2tm1b(EUCOMM)Wtsi
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
2.41×10-05
Dnaja1
Dnaja1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.41×10-05
Kcnj16
Kcnj16tm1Sjtu
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
2.49×10-05
Adra2a
Adra2atm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.50×10-05
Nlk
Nlktm2b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
2.53×10-05
C1qc
C1qcem1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
2.58×10-05
Gnptg
Gnptgem1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.58×10-05
Tnrc6b
Tnrc6bem1(IMPC)Bay
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.60×10-05
Cox7a2l
Cox7a2lem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.61×10-05
Dixdc1
Dixdc1tm1.1(KOMP)Vlcg
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.64×10-05
Msh5
Msh5tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.64×10-05
Pjvk
Pjvkem1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.70×10-05
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.71×10-05
Kif1b
Kif1btm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.79×10-05
Clic6
Clic6em1(IMPC)Mbp
HOM   Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
2.83×10-05
Vps13b
Vps13bem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.84×10-05
Asic1
Asic1em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.88×10-05
Ube2o
Ube2otm1.1(KOMP)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.89×10-05
Hbp1
Hbp1not yet available
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.93×10-05
Cep170b
Cep170bem1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.99×10-05
Id3
Id3em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.99×10-05
Snap23
Snap23tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.02×10-05
Tmco3
Tmco3tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.05×10-05
Arrdc1
Arrdc1tm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.06×10-05
Nfatc3
Nfatc3tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.10×10-05
Ctsa
Ctsatm2b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
3.11×10-05
Sytl4
Sytl4em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.12×10-05
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.12×10-05
Gsto1
Gsto1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.20×10-05
Riok3
Riok3em1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.22×10-05
Osbpl8
Osbpl8em1(IMPC)Tcp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.25×10-05
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.26×10-05
Fam83g
Fam83gtm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
3.32×10-05
Boc
Boctm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.34×10-05
Plekhf2
Plekhf2em1(IMPC)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.34×10-05
Celsr1
Celsr1Scy
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
3.35×10-05
Psen1
Psen1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.46×10-05
Cdkn1b
Cdkn1bem2(IMPC)H
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
3.47×10-05
Nr1d2
Nr1d2tm1Dgen
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.49×10-05
Gnasas1
Gnasas1tm2.1Jop
HET   Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
3.54×10-05
Triobp
Triobpem1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.56×10-05
Chst12
Chst12em1(IMPC)Marc
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
3.60×10-05
Timp2
Timp2em1(IMPC)Hmgu
HOM Late adult abnormal startle reflex Startle response
SHIRPA
HMGU
IMPC
3.61×10-05
Fgf11
Fgf11tm1a(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
3.63×10-05
Naaladl2
Naaladl2em1(IMPC)Tcp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.63×10-05
Nedd4l
Nedd4ltm1b(KOMP)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.63×10-05
Ube2a
Ube2atm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.65×10-05
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.69×10-05
Naxe
Naxetm1b(EUCOMM)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.72×10-05
Nolc1
Nolc1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.73×10-05
Marchf7
Marchf7March7
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
3.82×10-05
Mapk6
Mapk6em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.85×10-05
Cuedc1
Cuedc1em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.86×10-05
Rab10
Rab10em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.89×10-05
Il10ra
Il10ratm1b(KOMP)Wtsi
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
3.90×10-05
Prss54
Prss54em1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
3.91×10-05
Jakmip2
Jakmip2em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.93×10-05
Rabl2
Rabl2tm1.1(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.97×10-05
Paqr6
Paqr6tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
4.01×10-05
Tprn
Tprntm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.02×10-05
Tmem183a
Tmem183aTg(TMEM183B)1Pbo
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
HMGU
EuroPhenome
4.02×10-05
Gcgr
Gcgrtm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.06×10-05
Slc25a10
Slc25a10tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.12×10-05
Nr6a1
Nr6a1Nr6a1
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.12×10-05
Esd
Esdem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.19×10-05
Fgf20
Fgf20em1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
4.19×10-05
Esrra
Esrratm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.28×10-05
Ss18
Ss18em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.41×10-05
Npc1
Npc1tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.52×10-05
Setdb2
Setdb2tm1a(KOMP)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
4.57×10-05
Phf14
Phf14em1(IMPC)Hmgu
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.61×10-05
Ypel3
Ypel3tm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.63×10-05
Ppil1
Ppil1em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.76×10-05
Tph2
Tph2em1(IMPC)Mbp
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.77×10-05
Strap
StrapStrap
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.78×10-05
Clptm1
Clptm1em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.83×10-05
Gria1
Gria1em1(IMPC)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.99×10-05
Baz1b
Baz1btm2a(KOMP)Wtsi
HET   Early adult abnormal startle reflex Startle response
Modified SHIRPA
WTSI
EuroPhenome
5.10×10-05
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MRC Harwell
IMPC
5.17×10-05
Orc5
Orc5tm1a(EUCOMM)Wtsi
HET   Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
5.19×10-05
Stambp
Stambptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
5.26×10-05
Churc1
Churc1tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
5.27×10-05
Map3k1
Map3k1Gt(YTC001)Byg
HET Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
5.41×10-05
Hmbs
Hmbstm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.58×10-05
Timp4
Timp4em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
5.61×10-05
Tmub2
Tmub2tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
5.64×10-05
Arsj
Arsjem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.78×10-05
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.81×10-05
Col5a1
Col5a1tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.88×10-05
Miga1
Miga1tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.91×10-05
Meis1
Meis1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.98×10-05
Ang
Angtm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.00×10-05
Plscr1
Plscr1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.02×10-05
Pkig
Pkigtm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.04×10-05
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.12×10-05
Fbxo41
Fbxo41tm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.26×10-05
Dyrk1b
Dyrk1btm1b(EUCOMM)Wtsi
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.32×10-05
Tnfaip8l1
Tnfaip8l1em1(IMPC)Mbp
HOM Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
6.40×10-05
Slc27a3
Slc27a3em1(IMPC)Tcp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.59×10-05
Cd22
Cd22tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.76×10-05
Irgc
Irgcem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.77×10-05
Tlcd3b
Tlcd3bem1(IMPC)Bay
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
6.79×10-05
Taf15
Taf15em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.81×10-05
Cdkn2aip
Cdkn2aipem1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.83×10-05
Cttnbp2nl
Cttnbp2nlem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.90×10-05
Ebf1
Ebf1em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.92×10-05
Adgrv1
Adgrv1tm1.1(KOMP)Vlcg
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.01×10-05
Vgll3
Vgll3em1(IMPC)H
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
7.05×10-05
Ddx6
Ddx6em1(IMPC)Mbp
HET Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.09×10-05
Cndp2
Cndp2em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.09×10-05
Gsk3a
Gsk3atm1b(EUCOMM)Hmgu
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.10×10-05
Rilpl1
Rilpl1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.30×10-05
Clic5
Clic5tm1b(EUCOMM)Hmgu
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
7.35×10-05
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.54×10-05
Atp13a3
Atp13a3em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.60×10-05
Pla2g7
Pla2g7em1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.65×10-05
Tap1
Tap1tm2b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.84×10-05
Sfrp2
Sfrp2C50F
HOM Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.85×10-05
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
7.94×10-05
Anxa6
Anxa6tm1(NCOM)Cmhd
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
CMHD
EuroPhenome
8.00×10-05
Selenot
Selenotem1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.00×10-05
Dnaaf2
Dnaaf2tm1.1(KOMP)Vlcg
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.01×10-05
Elmod3
Elmod3em1(IMPC)J
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.12×10-05
Spta1
Spta1em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
8.16×10-05
Ube2m
Ube2mtm1.1(KOMP)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.23×10-05
Casp2
Casp2em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.27×10-05
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.34×10-05
Aqp9
Aqp9tm1b(KOMP)Wtsi
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
8.44×10-05
Ube2j2
Ube2j2em1(IMPC)Rbrc
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
RBRC
IMPC
8.48×10-05
Ttll1
Ttll1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
8.53×10-05
Nodal
Nodaltm1Rob
HET   Early adult abnormal startle reflex Startle response
Modified SHIRPA
MRC Harwell
EuroPhenome
8.58×10-05
Lrsam1
Lrsam1em1(IMPC)Bay
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
8.58×10-05
Spin1
Spin1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.65×10-05
Spred1
Spred1em1(IMPC)Ccpcz
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
CCP-IMG
IMPC
8.75×10-05
Dnmbp
Dnmbpem1(IMPC)Mbp
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.93×10-05
Cyb5d2
Cyb5d2tm1.1(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.94×10-05
Fam185a
Fam185aem1(IMPC)Ccpcz
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
9.12×10-05
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
9.12×10-05
Otogl
Otoglem1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.28×10-05
Spink12
Spink12em1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.28×10-05
Apmap
Apmapem1(IMPC)J
HOM Late adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
JAX
IMPC
9.28×10-05
Gng12
Gng12em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.30×10-05
Irf4
Irf4em1(IMPC)Mbp
HOM Middle aged adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
UC Davis
IMPC
9.37×10-05
Rtn4
Rtn4em1(IMPC)Hmgu
HOM   Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
HMGU
IMPC
9.43×10-05
Fshr
Fshrtm1(KOMP)Vlcg
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MARC
IMPC
9.45×10-05
Phf3
Phf3em2(IMPC)Marc
HOM Early adult abnormal startle reflex Startle response
Combined SHIRPA and Dysmorphology
MARC
IMPC
9.45×10-05
Npas3
Npas3tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
9.49×10-05
Gsta4
Gsta4tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
9.51×10-05
Dhx30
Dhx30tm1.1(KOMP)Vlcg
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.52×10-05
Rcor3
Rcor3em1(IMPC)J
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.73×10-05
Zfp422
Zfp422em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.83×10-05
Sstr5
Sstr5em1(IMPC)Mbp
HOM Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
9.85×10-05
Ostf1
Ostf1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
9.89×10-05
Entrep1
Entrep1em1(IMPC)Bay
HOM   Early adult decreased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
9.90×10-05

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 The way we measure

 Phenotype associations stats

7.12% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal startle reflex (503/7068)

2.18% females (163/7474) 4.47% males (334/7469)

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