Phenotype: decreased anxiety-related response

Definition
when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests
Synonyms
reduced anxiety in elevated zero maze test,  reduced anxiety,  reduced anxiety in dark-light crossing task,  decreased anxiety,  reduced anxiety in elevated plus maze test
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased anxiety-related response

Total number of significant genotype-phenotype associations: 23

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Htr1b
Htr1btm1.1(KOMP)Vlcg
HET Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 1.97×10-11
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 2.26×10-10
Adamtsl4
Adamtsl4em1(IMPC)J
HOM Late adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 1.37×10-09
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 4.15×10-07
Rnf214
Rnf214em1(IMPC)J
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 8.02×10-07
Egfem1
Egfem1em1(IMPC)J
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 1.00×10-06
Dcaf10
Dcaf10tm1.1(KOMP)Vlcg
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 1.01×10-06
Tppp
Tppptm1.1(KOMP)Vlcg
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 1.27×10-06
Igsf9b
Igsf9bem1(IMPC)J
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 2.32×10-06
Zfp42
Zfp42tm1b(KOMP)Mbp
HET Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 4.23×10-05
Dnajc9
Dnajc9tm1.1(KOMP)Vlcg
HET Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 4.35×10-05
Ovol1
Ovol1tm1b(KOMP)Wtsi
HET Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 6.57×10-05
Ppp1r26
Ppp1r26tm1.1(KOMP)Vlcg
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 6.85×10-05
Arid3a
Arid3atm1b(KOMP)Wtsi
HET Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 6.96×10-05
Rab24
Rab24tm1.1(KOMP)Wtsi
HOM Early adult decreased anxiety-related response Light-Dark Test | Fecal boli JAX | IMPC 9.29×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Light-Dark Test

 Phenotype associations stats

1.28% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased anxiety-related response (15/1172)

0.69% females (8/1157) 1.28% males (15/1168)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter