Phenotype: excessive tearing

Definition
an unusually high amount of fluid in the eye, either oversecreted by the lacrimal glands, or due to imperfect drainage by the tear conducting passages, often resulting in overflow of fluid from the eye onto the cheek
Synonyms
excessive lachrymation,  epiphora,  excessive lacrimation,  lacrimous eye,  watering eye
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with excessive tearing

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Spns2
Spns2tm1a(KOMP)Wtsi
HOM Early adult excessive tearing Modified SHIRPA | Lacrimation WTSI | EuroPhenome 5.58×10-06
Nsun2
Nsun2tm1a(EUCOMM)Wtsi
HET Early adult excessive tearing Modified SHIRPA | Lacrimation WTSI | EuroPhenome 6.89×10-05

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 The way we measure

 Phenotype associations stats

0.14% of tested genes with null mutations on a B6N genetic background have a phenotype association to excessive tearing (2/1450)

0.15% females (2/1349) 0.00% males (0/1327)

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