Definition
any structural anomaly of the vertebrae anterior to the sacrum
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal presacral vertebrae morphology
Total number of significant genotype-phenotype associations: 19
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Rbm22 Rbm22em1(IMPC)Mbp |
HET | Early adult | abnormal lumbar vertebrae morphology | Number of lumbar vertebrae X-ray |
UC Davis IMPC |
2.90×10-12 | |
| Tfap4 Tfap4tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal lumbar vertebrae morphology | Number of lumbar vertebrae X-ray |
UC Davis IMPC |
7.79×10-12 | |
| Slc6a5 Slc6a5tm1.1(KOMP)Vlcg |
HET | Early adult | abnormal lumbar vertebrae morphology | Number of lumbar vertebrae X-ray |
UC Davis IMPC |
1.27×10-08 | |
| Asxl1 Asxl1tm1a(EUCOMM)Wtsi |
HET | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI MGP |
7.54×10-08 | |
| Dscc1 Dscc1tm1a(KOMP)Wtsi |
HOM | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI MGP |
1.89×10-06 | |
| Efna1 Efna1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI EuroPhenome |
1.89×10-06 | |
| Ppp5c Ppp5ctm1a(EUCOMM)Wtsi |
HOM | Early adult | increased thoracic vertebrae number | Number of thoracic vertebrae X-Ray |
WTSI EuroPhenome |
3.85×10-06 | |
| Ezh2 Ezh2tm1a(EUCOMM)Wtsi |
HET | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI MGP |
4.90×10-06 | |
| Brdt Brdttm1a(EUCOMM)Wtsi |
HOM | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI EuroPhenome |
5.18×10-06 | |
| Ppp5c Ppp5ctm1a(EUCOMM)Wtsi |
HOM | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI EuroPhenome |
5.18×10-06 | |
| Mta1 Mta1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased lumbar vertebrae number | Number of lumbar vertebrae X-Ray |
WTSI EuroPhenome |
5.77×10-06 | |
| Mta1 Mta1tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased lumbar vertebrae number | Number of lumbar vertebrae X-Ray |
WTSI EuroPhenome |
9.14×10-06 | |
| Stx8 Stx8tm2a(EUCOMM)Wtsi |
HOM | Early adult | increased lumbar vertebrae number | Number of lumbar vertebrae X-ray |
WTSI MGP |
1.02×10-05 | |
| Pcgf2 Pcgf2tm1b(KOMP)Mbp |
HET | Early adult | abnormal lumbar vertebrae morphology | Number of lumbar vertebrae X-ray |
UC Davis IMPC |
2.67×10-05 | |
| R3hdm1 R3hdm1tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal lumbar vertebrae morphology | Number of lumbar vertebrae X-ray |
UC Davis IMPC |
2.67×10-05 |