Definition
any structural anomaly of bone that has a lattice-like or spongy structure; it is highly vascular and contains intercommunicating spaces filled with bone marrow
Synonyms
abnormal spongy substance morphology,
abnormal cancellous bone morphology,
abnormal substantia trabecularis morphology,
abnormal spongy bone morphology,
abnormal spongy spongiosa morphology
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal trabecular bone morphology
Total number of significant genotype-phenotype associations: 5
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Tead3 Tead3tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased bone trabecular spacing | Trabecular Spacing (mm) Trabecular Bone MicroCT |
WTSI IMPC |
2.31×10-10 | |
| Acbd5 Acbd5tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased bone trabecular spacing | Trabecular Spacing (mm) Trabecular Bone MicroCT |
WTSI IMPC |
5.42×10-09 | |
| Acbd5 Acbd5tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased bone trabecula number | Trabecular Number (mm-1) Trabecular Bone MicroCT |
WTSI IMPC |
8.50×10-07 | |
| Tmem18 Tmem18tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased bone trabecular spacing | Trabecular Spacing (mm) Trabecular Bone MicroCT |
WTSI IMPC |
4.25×10-06 | |
| Tead3 Tead3tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased bone trabecula number | Trabecular Number (mm-1) Trabecular Bone MicroCT |
WTSI IMPC |
2.12×10-05 |