Significant MP calls for KMPC Strains (IMPC_001)
Total number of results: 437
| Gene / Allele | Procedure | Parameter | Zygosity | Sex | Phenotype | P-value | Graph |
|---|---|---|---|---|---|---|---|
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Severely Dysmorphic | homozygote |
|
abnormal embryo development | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Edema | homozygote |
|
edema | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Gross Pathology and Tissue Collection | Seminal vesicle | homozygote |
|
abnormal seminal vesicle morphology | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E14.5-E15.5 | Edema | homozygote |
|
edema | 0.0 | |
| Hdac2 Hdac2em1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Tmem170b Tmem170bem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous animals viability | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
| Tmem41b Tmem41btm1b(KOMP)Wtsi |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Cep128 Cep128em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Head size | homozygote |
|
abnormal head size | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Edema | homozygote |
|
edema | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Embryo turning | homozygote |
|
abnormal embryo turning | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Hdac2 Hdac2em1(IMPC)Kmpc |
Viability Primary Screen | Homozygous males viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous animals viability | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Krt26 Krt26em1(IMPC)Kmpc |
Gross Pathology and Tissue Collection | Seminal vesicle | homozygote |
|
abnormal seminal vesicle morphology | 0.0 | |
| Ik Ikem2(IMPC)Kmpc |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
| Cep128 Cep128em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Pericardium Morphology | homozygote |
|
abnormal pericardium morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Vascular morphology | homozygote |
|
abnormal blood vessel morphology | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Pale yolk sac | homozygote |
|
pale yolk sac | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Pericardium Morphology | homozygote |
|
abnormal pericardium morphology | 0.0 | |
| Idh3a Idh3aem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous animals viability | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Eye Morphology | homozygote |
|
abnormal eye morphology | 0.0 | |
| Tmem41b Tmem41btm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Head shape | homozygote |
|
abnormal head shape | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Cleft palate | homozygote |
|
cleft palate | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Viability E18.5 Secondary Screen | Outcome | homozygote | prenatal lethality | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Hemorrhage | homozygote |
|
hemorrhage | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Hemorrhage | homozygote |
|
hemorrhage | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Head size | homozygote |
|
abnormal head size | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Microphthalmia | homozygote |
|
microphthalmia | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Idh3a Idh3aem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Microphthalmia | homozygote |
|
microphthalmia | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Visceral yolk sac morphology | homozygote |
|
abnormal visceral yolk sac morphology | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Cleft palate | homozygote |
|
cleft palate | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| E2f3 E2f3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Tars2 Tars2tm1b(EUCOMM)Hmgu |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Edema | homozygote |
|
edema | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Vascular morphology | homozygote |
|
abnormal blood vessel morphology | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Pale yolk sac | homozygote |
|
pale yolk sac | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E12.5 | Tail Morphology | homozygote |
|
abnormal tail morphology | 0.0 | |
| Ctdp1 Ctdp1em1(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Ctdp1 Ctdp1em1(IMPC)Kmpc |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Hindbrain morphology | homozygote |
|
abnormal hindbrain morphology | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Severely Dysmorphic | homozygote |
|
abnormal embryo development | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous males viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Hindbrain morphology | homozygote |
|
abnormal hindbrain morphology | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Ik Ikem2(IMPC)Kmpc |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Pale yolk sac | homozygote |
|
pale yolk sac | 0.0 | |
| Hdac2 Hdac2em1(IMPC)Kmpc |
Viability Primary Screen | Homozygous animals viability | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Tmem132e Tmem132eem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous animals viability | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| E2f3 E2f3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Tmem170b Tmem170bem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous males viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Eye Morphology | homozygote |
|
abnormal eye morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Hemorrhage | homozygote |
|
hemorrhage | 0.0 | |
| E2f3 E2f3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Edema | homozygote |
|
edema | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Ik Ikem2(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo turning | homozygote |
|
abnormal embryo turning | 0.0 | |
| E2f3 E2f3tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Tmem41b Tmem41btm1b(KOMP)Wtsi |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Cep128 Cep128em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Pald1 Pald1em1(IMPC)Kmpc |
Gross Pathology and Tissue Collection | Eye with optic nerve | homozygote |
|
abnormal eye morphology | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Pale yolk sac | homozygote |
|
pale yolk sac | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Tmem170b Tmem170bem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Phf7 Phf7tm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote |
|
male infertility | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Hemorrhage | homozygote |
|
hemorrhage | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | homozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Myc Mycem1(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Dapk3 Dapk3tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Irx6 Irx6tm1b(KOMP)Mbp |
Gross Pathology and Tissue Collection | Eye with optic nerve | homozygote |
|
abnormal eye morphology | 0.0 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Obp2b Obp2bem1(IMPC)Kmpc |
Gross Pathology and Tissue Collection | Kidney | homozygote |
|
abnormal kidney morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Visceral yolk sac morphology | homozygote |
|
abnormal visceral yolk sac morphology | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Ctdp1 Ctdp1em1(IMPC)Kmpc |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Obp2b Obp2bem1(IMPC)Kmpc |
Gross Pathology and Tissue Collection | Kidney | homozygote |
|
enlarged kidney | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Tars2 Tars2tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Idh3a Idh3aem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous males viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Tars2 Tars2tm1b(EUCOMM)Hmgu |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
| Obp2b Obp2bem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E14.5-E15.5 | Head shape | homozygote |
|
abnormal head shape | 0.0 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Cyb5b Cyb5btm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E12.5 | Tail Morphology | homozygote |
|
abnormal tail morphology | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Thsd7b Thsd7bem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, incomplete penetrance | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E14.5-E15.5 | Edema | homozygote |
|
edema | 0.0 | |
| Tmem132e Tmem132eem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous females viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Tmem132e Tmem132eem1(IMPC)Kmpc |
Viability Primary Screen | Homozygous males viability | homozygote |
|
preweaning lethality, complete penetrance | 0.0 | |
| Slc25a1 Slc25a1em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Cep128 Cep128em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Gross Pathology and Tissue Collection | Seminal vesicle | homozygote |
|
absent seminal vesicle | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo turning | homozygote |
|
abnormal embryo turning | 0.0 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Gross Morphology Embryo E12.5 | Delayed embryonic development | homozygote |
|
embryonic growth retardation | 0.0 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Responsive to tactile stimuli | heterozygote |
|
unresponsive to tactile stimuli | 0.0 | |
| Rtp4 Rtp4tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
| Asb2 Asb2tm2b(KOMP)Wtsi |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote |
|
abnormal embryo size | 0.0 | |
| Ammecr1l Ammecr1lem1(IMPC)Kmpc |
Gross Morphology Embryo E18.5 | Spontaneous movement | homozygote |
|
no spontaneous movement | 0.0 | |
| Cav2 Cav2em1(IMPC)Kmpc |
Gross Pathology and Tissue Collection | Eye with optic nerve | homozygote |
|
abnormal eye morphology | 0.0 | |
| E2f3 E2f3tm1b(KOMP)Wtsi |
Gross Morphology Embryo E18.5 | Spontaneous movement | heterozygote |
|
no spontaneous movement | 0.0 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Gross Morphology Embryo E9.5 | Vitelline vasculature morphology | homozygote |
|
abnormal vitelline vasculature morphology | 0.0 | |
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Hematology | Mean platelet volume | homozygote |
|
increased mean platelet volume | 3.179256714913344E-33 | |
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Hematology | Mean platelet volume | homozygote |
|
increased mean platelet volume | 2.5941411608351037E-27 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q1) | heterozygote |
|
increased Ly6C-positive immature NK cell number | 8.508842310773988E-26 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q1) | heterozygote |
|
increased Ly6C-positive immature NK cell number | 1.6903145074945892E-23 | |
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Indirect Calorimetry | Respiratory Exchange Ratio | homozygote |
|
decreased respiratory quotient | 3.0726102067073845E-20 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Skin color - ear | homozygote |
|
abnormal skin coloration | 3.5287217323721867E-19 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb grip strength measurement mean | homozygote |
|
decreased grip strength | 1.0793460019043587E-18 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote |
|
abnormal coat/hair pigmentation | 1.587924890719879E-17 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote |
|
abnormal coat/hair pigmentation | 1.587924890719879E-17 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote |
|
decreased grip strength | 6.547286087845434E-17 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb grip strength measurement mean | homozygote |
|
decreased grip strength | 1.0852970949187286E-16 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote |
|
abnormal coat/hair pigmentation | 1.74671733016103E-16 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 1.384064647186854E-15 | |
| Klf4 Klf4em1(IMPC)Kmpc |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote |
|
decreased grip strength | 2.2990187312617533E-15 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote |
|
decreased bone mineral content | 4.6159992196865077E-14 | |
| Hdac11 Hdac11em1(IMPC)Kmpc |
Clinical Chemistry | Alanine aminotransferase | homozygote |
|
increased circulating alanine transaminase level | 1.0266061682391928E-13 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Digit integrity | homozygote |
|
abnormal digit morphology | 1.0657216076423101E-13 | |
| Zfp746 Zfp746tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat mass | homozygote |
|
increased total body fat amount | 1.610071396953433E-13 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
decreased fasting circulating glucose level | 1.5099756297751177E-12 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - back | heterozygote |
|
abnormal coat/hair pigmentation | 2.8368626892039117E-12 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - head | heterozygote |
|
abnormal coat/hair pigmentation | 2.8368626892039117E-12 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote |
|
decreased grip strength | 3.46470356744899E-12 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote |
|
decreased bone mineral density | 4.606623676267629E-12 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q3) | heterozygote |
|
decreased Ly6C-positive immature NK cell number | 1.3980097461618879E-11 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | heterozygote |
|
abnormal coat/hair pigmentation | 2.118032832454375E-11 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Number of digits | homozygote | abnormal digit morphology | 3.005578771975159E-11 | ||
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote |
|
decreased total body fat amount | 7.490110615071544E-11 | |
| Qsox2 Qsox2em1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
increased fasting circulating glucose level | 9.054183097711999E-11 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote |
|
decreased grip strength | 9.283857710373766E-11 | |
| Qsox2 Qsox2em1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
increased fasting circulating glucose level | 1.0152578083788555E-10 | |
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Clinical Chemistry | Creatine kinase | homozygote |
|
increased circulating creatine kinase level | 2.0411913825846284E-10 | |
| Cav3 Cav3em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote |
|
increased prepulse inhibition | 3.4786715175094685E-10 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
decreased fasting circulating glucose level | 3.708138240909875E-10 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - back | heterozygote |
|
abnormal coat/hair pigmentation | 5.385993873119332E-10 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - head | heterozygote |
|
abnormal coat/hair pigmentation | 5.385993873119332E-10 | |
| Dapl1 Dapl1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 7.564636139711922E-10 | |
| Dapk3 Dapk3tm1b(EUCOMM)Hmgu |
Fear Conditioning | Cue Baseline % Freezing Time | heterozygote |
|
increased freezing behavior | 9.796098376924078E-10 | |
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Clinical Chemistry | Alanine aminotransferase | homozygote |
|
increased circulating alanine transaminase level | 1.185040732210041E-9 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Digit integrity | homozygote |
|
abnormal digit morphology | 1.4793035685300993E-9 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Skin color - tail | homozygote |
|
abnormal skin coloration | 2.3015600536524516E-9 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q3) | heterozygote |
|
decreased Ly6C-positive immature NK cell number | 2.3679447291868883E-9 | |
| Ehf Ehfem1(IMPC)Kmpc |
Hematology | Hematocrit | homozygote |
|
decreased hematocrit | 2.5652402424469756E-9 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote |
|
increased lean body mass | 3.113305613311468E-9 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | heterozygote |
|
abnormal coat/hair pigmentation | 3.210343990645015E-9 | |
| Lingo2 Lingo2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Body length | homozygote |
|
increased body length | 4.245240603495404E-9 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Open Field | Distance travelled - total | heterozygote |
|
hyperactivity | 4.6278683107914276E-9 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Skin color - ear | homozygote |
|
abnormal skin coloration | 4.841696821245023E-9 | |
| Dapl1 Dapl1em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote |
|
decreased exploration in new environment | 8.064677814445531E-9 | |
| Krt32 Krt32em1(IMPC)Kmpc |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote |
|
increased blood urea nitrogen level | 9.789240529300969E-9 | |
| Zfp746 Zfp746tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote |
|
increased lean body mass | 1.2564891349597929E-8 | |
| Etv4 Etv4em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 1.590049691913009E-8 | |
| Etv4 Etv4em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 2.7127772028734398E-8 | |
| Dapk3 Dapk3tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | heterozygote |
|
hyperactivity | 3.232927525687046E-8 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Hematology | Hematocrit | homozygote |
|
increased hematocrit | 4.659083785440998E-8 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Brachydactyly | homozygote |
|
brachydactyly | 6.614081371481006E-8 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote |
|
decreased bone mineral content | 7.36757712616054E-8 | |
| Dapk3 Dapk3tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | heterozygote |
|
hyperactivity | 8.000034767974284E-8 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote |
|
decreased bone mineral content | 9.085754015814018E-8 | |
| Dapl1 Dapl1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote |
|
decreased bone mineral density | 9.861015826118091E-8 | |
| Ehf Ehfem1(IMPC)Kmpc |
Hematology | Platelet count | homozygote |
|
thrombocytosis | 1.0746254019977641E-7 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Heart Weight | Tibia length | homozygote |
|
short tibia | 1.0749224088613119E-7 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Immunophenotyping | CD8 CD25+ T cells | heterozygote |
|
increased CD8-positive, CD25-positive alpha-beta T cell number | 1.3026209444433334E-7 | |
| Rtp4 Rtp4tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 1.4683106996926654E-7 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Brachydactyly | homozygote |
|
brachydactyly | 2.2189553305906884E-7 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote |
|
decreased grip strength | 2.3122430548028206E-7 | |
| Emd Emdem1(IMPC)Kmpc |
Clinical Chemistry | Phosphorus | hemizygote |
|
increased circulating phosphate level | 2.683980255824281E-7 | |
| Myc Mycem1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote |
|
increased startle reflex | 4.1178756760018587E-7 | |
| Myc Mycem1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Body length | heterozygote |
|
decreased body length | 4.810281666323135E-7 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote |
|
increased grip strength | 5.050968070463568E-7 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 5.519587489288824E-7 | |
| Sdk1 Sdk1em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 5.650346679431095E-7 | |
| Ldaf1 Ldaf1em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote | hyperactivity | 5.850882303093385E-7 | ||
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote |
|
abnormal coat/hair pigmentation | 5.973778343104641E-7 | |
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote |
|
abnormal coat/hair pigmentation | 5.973778343104641E-7 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote |
|
increased total body fat amount | 6.260126497181773E-7 | |
| Emd Emdem1(IMPC)Kmpc |
Clinical Chemistry | Phosphorus | homozygote |
|
increased circulating phosphate level | 7.699881052758428E-7 | |
| Lingo2 Lingo2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Fat mass | homozygote |
|
decreased total body fat amount | 8.426586077803222E-7 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Cholesterol ratio | heterozygote |
|
abnormal cholesterol homeostasis | 8.831000855025195E-7 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | heterozygote |
|
increased circulating alkaline phosphatase level | 8.881264079718676E-7 | |
| Lingo2 Lingo2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Lean mass | homozygote |
|
increased lean body mass | 9.503600608695706E-7 | |
| Cav2 Cav2em1(IMPC)Kmpc |
Clinical Chemistry | Alanine aminotransferase | homozygote |
|
increased circulating alanine transaminase level | 1.187538032354496E-6 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Indirect Calorimetry | Total food intake | heterozygote |
|
decreased food intake | 1.3345021443456062E-6 | |
| Mreg Mregtm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.5738118008812307E-6 | ||
| Tspan5 Tspan5em1(IMPC)Kmpc |
Open Field | Whole arena resting time | homozygote |
|
hyperactivity | 1.6435523093605298E-6 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Open Field | Whole arena average speed | heterozygote |
|
hyperactivity | 1.6588214748480823E-6 | |
| Myc Mycem1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote |
|
decreased bone mineral content | 1.71783597124886E-6 | |
| Nrsn2 Nrsn2em1(IMPC)Kmpc |
Clinical Chemistry | Uric acid | homozygote |
|
increased blood uric acid level | 1.722724732644565E-6 | |
| Cxcl5 Cxcl5em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote |
|
decreased startle reflex | 1.7689720834823675E-6 | |
| Mir129-2 Mir129-2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 1.811913534766063E-6 | |
| Dapl1 Dapl1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 1.8712211158344871E-6 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Open Field | Distance travelled - total | homozygote | hyperactivity | 1.8919962485597352E-6 | ||
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote |
|
increased lean body mass | 2.1943287720205262E-6 | |
| Mreg Mregtm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.3125837742554722E-6 | ||
| Mir100 Mir100em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote |
|
abnormal coat/hair pigmentation | 2.317352937097894E-6 | |
| Zfp746 Zfp746tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote |
|
decreased bone mineral density | 2.459640427332488E-6 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | increased grip strength | 2.6280436031811405E-6 | ||
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Hematology | Red blood cell count | homozygote |
|
increased erythrocyte cell number | 2.8437045784812653E-6 | |
| Pank4 Pank4em1(IMPC)Kmpc |
Fear Conditioning | Cue Baseline % Freezing Time | homozygote |
|
increased freezing behavior | 2.8805936835851753E-6 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote |
|
decreased bone mineral content | 2.9950938369438518E-6 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Open Field | Whole arena average speed | homozygote | hyperactivity | 3.1584588668920333E-6 | ||
| Cav3 Cav3em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote |
|
increased prepulse inhibition | 3.196248599124374E-6 | |
| Myc Mycem1(IMPC)Kmpc |
X-ray | Tibia length | heterozygote |
|
short tibia | 3.4732534004433546E-6 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | Eosinophils | heterozygote | increased eosinophil cell number | 3.549190068952157E-6 | ||
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote |
|
decreased lean body mass | 3.810605676335399E-6 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote |
|
decreased grip strength | 4.050265033583855E-6 | |
| Lrrn3 Lrrn3em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 4.278618234820897E-6 | |
| Tfpi2 Tfpi2em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 4.381292910693446E-6 | |
| Ehf Ehfem1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
decreased locomotor activity | 4.767590780829778E-6 | |
| Aqp9 Aqp9tm1b(KOMP)Wtsi |
X-ray | Tibia length | homozygote |
|
short tibia | 4.775504748977255E-6 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | CD4 CD44-CD62L+ T cells | heterozygote | decreased effector memory T-helper cell number | 5.149657226866111E-6 | ||
| Tpte Tpteem1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote | hyperactivity | 5.228962436376605E-6 | ||
| Col6a3 Col6a3em1(IMPC)Kmpc |
Clinical Chemistry | LDL-cholesterol | homozygote |
|
increased circulating LDL cholesterol level | 5.25346013091621E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote |
|
decreased prepulse inhibition | 5.306608727551065E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Open Field | Percentage center time | homozygote |
|
abnormal behavior | 5.39266011401196E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Open Field | Periphery permanence time | homozygote |
|
decreased thigmotaxis | 5.39266011401196E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Open Field | Center permanence time | homozygote |
|
decreased thigmotaxis | 5.39266011401196E-6 | |
| Ano4 Ano4em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote |
|
decreased bone mineral content | 5.4701536100765225E-6 | |
| Nrsn2 Nrsn2em1(IMPC)Kmpc |
Clinical Chemistry | Phosphorus | homozygote |
|
increased circulating phosphate level | 5.645573310175678E-6 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Grip Strength | Forelimb grip strength normalised against body weight | heterozygote | increased grip strength | 6.2358262766792905E-6 | ||
| Myc Mycem1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote |
|
increased startle reflex | 6.351071988319745E-6 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Eye Morphology | Retinal Blood Vessels Pattern | heterozygote |
|
abnormal retina blood vessel morphology | 6.358216978696873E-6 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Eye Morphology | Lens Opacity | homozygote |
|
cataract | 6.395246600732207E-6 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Eye Morphology | Lens | homozygote |
|
abnormal lens morphology | 6.395246600732207E-6 | |
| Ak4 Ak4em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 6.948231657588622E-6 | |
| Rtp4 Rtp4tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 7.060424195515225E-6 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Area | homozygote |
|
abnormal bone structure | 7.299637672986137E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote |
|
decreased bone mineral density | 7.376165285677416E-6 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | CD4 T cells | heterozygote |
|
increased CD4-positive, alpha-beta T cell number | 7.70506539993221E-6 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Immunophenotyping | cDCs CD11b Type | heterozygote |
|
increased CD11b-high dendritic cell number | 7.898556759755593E-6 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Immunophenotyping | CD8 CD25+ T cells | heterozygote |
|
increased CD8-positive, CD25-positive alpha-beta T cell number | 8.043240086408332E-6 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote |
|
increased total body fat amount | 8.289067409350537E-6 | |
| Myc Mycem1(IMPC)Kmpc |
Indirect Calorimetry | Total water intake | heterozygote |
|
decreased fluid intake | 8.38984124129638E-6 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 8.418243851338048E-6 | ||
| Dapl1 Dapl1em1(IMPC)Kmpc |
Heart Weight | Heart weight | homozygote |
|
decreased heart weight | 9.362541277369019E-6 | |
| Tpte Tpteem1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote | hyperactivity | 9.94361653283704E-6 | ||
| Tfpi2 Tfpi2em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 9.9699118436547E-6 | |
| Ldaf1 Ldaf1em1(IMPC)Kmpc |
Open Field | Whole arena resting time | homozygote | hyperactivity | 1.0642625056789257E-5 | ||
| Letmd1 Letmd1em1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
increased fasting circulating glucose level | 1.0657588063622825E-5 | |
| Krt32 Krt32em1(IMPC)Kmpc |
Hematology | Hemoglobin | homozygote |
|
increased hemoglobin content | 1.0684834705898538E-5 | |
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | increased grip strength | 1.0807351827679668E-5 | ||
| Tspan5 Tspan5em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 1.0970428775181063E-5 | |
| Lrrn3 Lrrn3em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote |
|
decreased bone mineral content | 1.1205359442101326E-5 | |
| Ik Ikem2(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Lean mass | heterozygote |
|
increased lean body mass | 1.156354664999526E-5 | |
| Lingo2 Lingo2em1(IMPC)Kmpc |
X-ray | Tibia length | homozygote |
|
long tibia | 1.2628726835828274E-5 | |
| Myc Mycem1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | heterozygote | decreased bone mineral density | 1.2972031981917098E-5 | ||
| Erap1 Erap1tm2b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote |
|
decreased bone mineral content | 1.4008202924742363E-5 | |
| Nsg2 Nsg2em1(IMPC)Kmpc |
Fear Conditioning | Difference in Conditioning Post-shock and Conditioning Baseline % Freezing | homozygote | abnormal freezing behavior | 1.430996780982241E-5 | ||
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Hematology | Platelet count | homozygote |
|
thrombocytopenia | 1.50568757817382E-5 | |
| Tmem86a Tmem86atm1b(KOMP)Mbp |
Heart Weight | Tibia length | homozygote |
|
short tibia | 1.5064419130794704E-5 | |
| Tpte Tpteem1(IMPC)Kmpc |
X-ray | Shape of spine | homozygote |
|
abnormal spine curvature | 1.5106105820450466E-5 | |
| Tpte Tpteem1(IMPC)Kmpc |
X-ray | Kyphosis | homozygote |
|
kyphosis | 1.5106105820450466E-5 | |
| Lrrn3 Lrrn3em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote |
|
decreased bone mineral density | 1.5837722457945347E-5 | |
| Gna14 Gna14em1(IMPC)Kmpc |
Clinical Chemistry | Cholesterol ratio | homozygote |
|
abnormal cholesterol homeostasis | 1.6960226275841706E-5 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Hematology | Hemoglobin | homozygote | increased hemoglobin content | 1.700594657449983E-5 | ||
| Spry4 Spry4tm1b(KOMP)Mbp |
X-ray | Tibia length | homozygote |
|
short tibia | 1.7046017092070542E-5 | |
| Ano4 Ano4em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote |
|
decreased bone mineral content | 1.8052516679745167E-5 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Area | homozygote |
|
abnormal bone structure | 1.814198367355857E-5 | |
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote |
|
impaired glucose tolerance | 1.9007822629646398E-5 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote |
|
increased startle reflex | 1.9131985027343035E-5 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote |
|
increased blood urea nitrogen level | 1.927762605191674E-5 | |
| Sdk1 Sdk1em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 1.9546430849004537E-5 | |
| Myc Mycem1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Area | heterozygote | abnormal bone structure | 2.024135028477758E-5 | ||
| Romo1 Romo1em1(IMPC)Kmpc |
Clinical Chemistry | Total protein | heterozygote |
|
increased circulating total protein level | 2.024450986937154E-5 | |
| Mdm1 Mdm1em1(IMPC)Kmpc |
Clinical Chemistry | Cholesterol ratio | homozygote |
|
abnormal cholesterol homeostasis | 2.0258972654119134E-5 | |
| Ano4 Ano4em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 2.0973506252630614E-5 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote |
|
decreased total body fat amount | 2.1274554455885664E-5 | |
| Pon3 Pon3tm1b(KOMP)Wtsi |
Clinical Chemistry | Triglycerides | homozygote |
|
increased circulating triglyceride level | 2.191979729104787E-5 | |
| Tmem175 Tmem175tm1b(KOMP)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | homozygote |
|
increased circulating aspartate transaminase level | 2.2061502022552304E-5 | |
| Stmn2 Stmn2em1(IMPC)Kmpc |
Clinical Chemistry | Creatine kinase | heterozygote |
|
increased circulating creatine kinase level | 2.239820605609566E-5 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Indirect Calorimetry | Respiratory Exchange Ratio | heterozygote |
|
decreased respiratory quotient | 2.254043829452712E-5 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Clinical Chemistry | Total bilirubin | heterozygote |
|
increased circulating bilirubin level | 2.3315582438954152E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q4) | heterozygote |
|
increased Ly6C-positive mature NK cell number | 2.3642944142920896E-5 | |
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote |
|
increased prepulse inhibition | 2.365956243011169E-5 | |
| Erap1 Erap1tm2b(EUCOMM)Wtsi |
Hematology | Platelet count | homozygote |
|
thrombocytosis | 2.520314956200309E-5 | |
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Clinical Chemistry | Alkaline phosphatase | homozygote |
|
increased circulating alkaline phosphatase level | 2.5709703550091945E-5 | |
| Ano4 Ano4em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 2.59694588748971E-5 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote |
|
decreased prepulse inhibition | 2.7262165531283244E-5 | |
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Fear Conditioning | Difference in Cue Tone and Cue Baseline % Freezing | homozygote | impaired cued conditioning behavior | 2.733845576585736E-5 | ||
| Tspan5 Tspan5em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 2.817148379108403E-5 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Grip Strength | Forelimb grip strength measurement mean | heterozygote |
|
increased grip strength | 2.85407186311204E-5 | |
| Aqp9 Aqp9tm1b(KOMP)Wtsi |
X-ray | Tibia | homozygote |
|
abnormal tibia morphology | 2.9996250304975547E-5 | |
| Cav3 Cav3em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote |
|
increased prepulse inhibition | 3.02428725262871E-5 | |
| Cxcl5 Cxcl5em1(IMPC)Kmpc |
Open Field | Whole arena average speed | homozygote | hyperactivity | 3.068730438826606E-5 | ||
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Subsets (Q4) | heterozygote |
|
increased Ly6C-positive mature NK cell number | 3.069036756642163E-5 | |
| Phgdh Phgdhtm1b(KOMP)Wtsi |
Indirect Calorimetry | Total water intake | heterozygote |
|
decreased fluid intake | 3.122975249425508E-5 | |
| Lingo2 Lingo2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote | increased bone mineral content | 3.153369834762998E-5 | ||
| Slc24a3 Slc24a3em1(IMPC)Kmpc |
Indirect Calorimetry | Total water intake | homozygote |
|
increased fluid intake | 3.1744006264489144E-5 | |
| Mir129-2 Mir129-2em1(IMPC)Kmpc |
Clinical Chemistry | Total protein | homozygote |
|
decreased circulating total protein level | 3.174686207785271E-5 | |
| Cxcl5 Cxcl5em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote | hyperactivity | 3.2146643206942827E-5 | ||
| Tspan13 Tspan13em1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote |
|
decreased fasting circulating glucose level | 3.216135883121751E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | T Cells (panel B) | heterozygote |
|
increased T cell number | 3.2242038287222385E-5 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi |
Open Field | Whole arena resting time | homozygote | hyperactivity | 3.248372740927152E-5 | ||
| Hdac11 Hdac11em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Body length | homozygote |
|
increased body length | 3.28286514559295E-5 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Lean mass | homozygote |
|
decreased lean body mass | 3.303403718746267E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NK Cells (panel B) | heterozygote | increased NK cell number | 3.373447179910727E-5 | ||
| Mir129-2 Mir129-2em1(IMPC)Kmpc |
X-ray | Tibia length | homozygote |
|
short tibia | 3.4381740988465026E-5 | |
| Tm4sf5 Tm4sf5em1(IMPC)Kmpc |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote |
|
increased grip strength | 3.4424796467646956E-5 | |
| Nrsn2 Nrsn2em1(IMPC)Kmpc |
Clinical Chemistry | Calcium | homozygote |
|
increased circulating calcium level | 3.518572702887468E-5 | |
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Clinical Chemistry | Glucose | homozygote |
|
decreased circulating glucose level | 3.529789682943374E-5 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Eye Morphology | Narrow eye opening | homozygote |
|
narrow eye opening | 3.544251012499444E-5 | |
| Ehf Ehfem1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote |
|
improved glucose tolerance | 3.602974902605638E-5 | |
| Ehf Ehfem1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
decreased locomotor activity | 3.6030342016601935E-5 | |
| Edem3 Edem3tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | heterozygote |
|
decreased bone mineral density | 3.6527548218145967E-5 | |
| Phf7 Phf7tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote |
|
increased grip strength | 3.8255468098213896E-5 | |
| Tmtc2 Tmtc2em2(IMPC)Kmpc |
Fear Conditioning | Difference in Context and Conditioning Baseline % Freezing | homozygote |
|
enhanced contextual conditioning behavior | 3.851951260003261E-5 | |
| Tmem132e Tmem132eem1(IMPC)Kmpc |
Fear Conditioning | Difference in Cue Tone and Cue Baseline % Freezing | heterozygote |
|
enhanced cued conditioning behavior | 3.87539439543616E-5 | |
| Dapl1 Dapl1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | decreased bone mineral content | 3.899939838447608E-5 | ||
| Ak4 Ak4em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | decreased bone mineral content | 3.977357118856162E-5 | ||
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - back | heterozygote |
|
abnormal coat/hair pigmentation | 4.0529608668293804E-5 | |
| Hdac7 Hdac7tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - color - head | heterozygote |
|
abnormal coat/hair pigmentation | 4.0529608668293804E-5 | |
| Tspan13 Tspan13em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote |
|
decreased prepulse inhibition | 4.1223705920856446E-5 | |
| Mir129-2 Mir129-2em1(IMPC)Kmpc |
Heart Weight | Tibia length | homozygote | short tibia | 4.231520142639056E-5 | ||
| Tmem175 Tmem175tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | increased prepulse inhibition | 4.5015614887233824E-5 | ||
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote | hyperactivity | 4.572601756080985E-5 | ||
| Mir129-2 Mir129-2em1(IMPC)Kmpc |
Heart Weight | Heart weight | homozygote |
|
increased heart weight | 4.5920107368147E-5 | |
| Col6a3 Col6a3em1(IMPC)Kmpc |
Clinical Chemistry | Cholesterol ratio | homozygote |
|
abnormal cholesterol homeostasis | 4.811542385141365E-5 | |
| Tm4sf5 Tm4sf5em1(IMPC)Kmpc |
Indirect Calorimetry | Total water intake | homozygote |
|
decreased fluid intake | 4.8496196541236714E-5 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | heterozygote | increased grip strength | 4.900180283584632E-5 | ||
| Klf4 Klf4em1(IMPC)Kmpc |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote |
|
decreased grip strength | 4.90888487547636E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | cDCs | heterozygote | increased dendritic cell number | 4.918509876006283E-5 | ||
| Mdm1 Mdm1em1(IMPC)Kmpc |
Heart Weight | Tibia length | homozygote |
|
short tibia | 4.9474147090222687E-5 | |
| Romo1 Romo1em1(IMPC)Kmpc |
Open Field | Distance travelled - total | heterozygote | hyperactivity | 5.015994975110516E-5 | ||
| Spry4 Spry4tm1b(KOMP)Mbp |
Eye Morphology | Corneal opacity | homozygote | corneal opacity | 5.099263580632396E-5 | ||
| Spry4 Spry4tm1b(KOMP)Mbp |
Eye Morphology | Cornea | homozygote | abnormal cornea morphology | 5.099263580632396E-5 | ||
| Ehf Ehfem1(IMPC)Kmpc |
Hematology | Hemoglobin | homozygote |
|
decreased hemoglobin content | 5.173199679120444E-5 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Immunophenotyping | DN CD25+ NKT cells | heterozygote | increased CD4-negative, CD25-positive NK T cell number | 5.3835054131923243E-5 | ||
| Irx6 Irx6tm1b(KOMP)Mbp |
Clinical Chemistry | Phosphorus | homozygote |
|
increased circulating phosphate level | 5.432856050902046E-5 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote |
|
increased grip strength | 5.676480213878676E-5 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 5.717475505662151E-5 | |
| Spry4 Spry4tm1b(KOMP)Mbp |
Open Field | Whole arena average speed | homozygote |
|
hyperactivity | 5.956095628789626E-5 | |
| Krt32 Krt32em1(IMPC)Kmpc |
Clinical Chemistry | Total cholesterol | homozygote |
|
increased circulating cholesterol level | 5.967432662146166E-5 | |
| Ldaf1 Ldaf1em1(IMPC)Kmpc |
Open Field | Distance travelled - total | homozygote |
|
hyperactivity | 5.998930646455847E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | T cells (panel A) | heterozygote | increased T cell number | 6.086192297516391E-5 | ||
| Myc Mycem1(IMPC)Kmpc |
Grip Strength | Forelimb grip strength normalised against body weight | heterozygote |
|
increased grip strength | 6.100204336689785E-5 | |
| Anxa13 Anxa13em1(IMPC)Kmpc |
Fear Conditioning | Conditioning Baseline % Freezing Time | homozygote |
|
increased freezing behavior | 6.211904837982729E-5 | |
| Edem1 Edem1em1(IMPC)Kmpc |
Hematology | Mean platelet volume | homozygote |
|
increased mean platelet volume | 6.287373253144324E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Immunophenotyping | NKT Subsets (Q1) | heterozygote | increased Ly6C-positive NK T cell number | 6.40627185930498E-5 | ||
| Letmd1 Letmd1em1(IMPC)Kmpc |
Fear Conditioning | Conditioning Baseline % Freezing Time | homozygote | increased freezing behavior | 6.407261389540508E-5 | ||
| Aldh1l1 Aldh1l1em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 6.555615982506424E-5 | ||
| Slc25a18 Slc25a18tm1b(KOMP)Wtsi |
Fear Conditioning | Difference in Context and Conditioning Baseline % Freezing | homozygote |
|
impaired contextual conditioning behavior | 6.569355173269287E-5 | |
| Col6a3 Col6a3em1(IMPC)Kmpc |
Eye Morphology | Corneal vascularization | homozygote | corneal vascularization | 6.603007204830647E-5 | ||
| Cav2 Cav2em1(IMPC)Kmpc |
Clinical Chemistry | Total protein | homozygote |
|
increased circulating total protein level | 6.768413732061163E-5 | |
| Zfp746 Zfp746tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote |
|
increased total body fat amount | 6.917901191627607E-5 | |
| Myc Mycem1(IMPC)Kmpc |
Indirect Calorimetry | Total water intake | heterozygote |
|
decreased fluid intake | 7.198398088803515E-5 | |
| Myc Mycem1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | heterozygote | decreased prepulse inhibition | 7.480388740077615E-5 | ||
| Tspan13 Tspan13em1(IMPC)Kmpc |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote |
|
increased grip strength | 7.484020170522854E-5 | |
| Tmem72 Tmem72tm1b(KOMP)Wtsi |
Hematology | Hematocrit | homozygote |
|
increased hematocrit | 7.568842556793243E-5 | |
| Pald1 Pald1em1(IMPC)Kmpc |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | increased prepulse inhibition | 7.990330777829513E-5 | ||
| Nsg2 Nsg2em1(IMPC)Kmpc |
Fear Conditioning | Difference in Cue Tone and Cue Baseline % Freezing | homozygote |
|
enhanced cued conditioning behavior | 8.113715739455074E-5 | |
| Ano4 Ano4em1(IMPC)Kmpc |
Clinical Chemistry | Cholesterol ratio | homozygote |
|
abnormal cholesterol homeostasis | 8.16067258710973E-5 | |
| Edem1 Edem1em1(IMPC)Kmpc |
Hematology | Mean platelet volume | homozygote |
|
increased mean platelet volume | 8.172208617907017E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote |
|
decreased total body fat amount | 8.193254325306043E-5 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote |
|
increased grip strength | 8.293856080854312E-5 | |
| Aqp9 Aqp9tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote |
|
decreased startle reflex | 8.442487160209566E-5 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | heterozygote |
|
increased circulating aspartate transaminase level | 8.456299838144332E-5 | |
| Cav3 Cav3em1(IMPC)Kmpc |
Clinical Chemistry | LDL-cholesterol | homozygote | increased circulating LDL cholesterol level | 8.659963350510225E-5 | ||
| Ehf Ehfem1(IMPC)Kmpc |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | decreased fasting circulating glucose level | 8.760009950492531E-5 | ||
| Pitpnc1 Pitpnc1em1(IMPC)Kmpc |
Clinical Chemistry | Albumin | homozygote |
|
increased circulating serum albumin level | 8.831162267597392E-5 | |
| Mreg Mregtm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote |
|
decreased body length | 9.063754987437278E-5 | |
| Krt35 Krt35em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Bone Area | homozygote | abnormal bone structure | 9.156327723758295E-5 | ||
| Aanat Aanatem1(IMPC)Krb |
Hematology | Mean platelet volume | homozygote | increased mean platelet volume | 9.197935287375003E-5 | ||
| Stmn2 Stmn2em1(IMPC)Kmpc |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote |
|
decreased total body fat amount | 9.339429379906505E-5 | |
| Krt32 Krt32em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote |
|
increased exploration in new environment | 9.453318489249796E-5 | |
| Tmem163 Tmem163em1(IMPC)Kmpc |
Combined SHIRPA and Dysmorphology | Coat - color pattern - back | homozygote |
|
abnormal coat/hair pigmentation | 9.482011228101328E-5 | |
| Npas3 Npas3tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote |
|
increased startle reflex | 9.493029938312247E-5 | |
| Ehf Ehfem1(IMPC)Kmpc |
Hematology | Red blood cell distribution width | homozygote |
|
increased red blood cell distribution width | 9.499678708380088E-5 | |
| E2f3 E2f3tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Snout size | heterozygote |
|
abnormal snout morphology | 9.556477016303688E-5 | |
| Qsox1 Qsox1em1(IMPC)Kmpc |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 9.723114635562524E-5 | ||
| Aqp9 Aqp9tm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.0297369337640703E-4 |