Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.; LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.; LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.; LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris ; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; LEFT EYE: Very small lesion ( bottom right).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus), slight dysplasia.; RIGHT EYE: Some debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.; LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: No data- severe lens opacity; difficult to image.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight corneal opacity, difficult to focus ; RIGHT EYE: Some rd8, some hemorrhage

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight corneal opacity, tiny hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris ; LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, white opacity difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, crystallized debris

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; LEFT EYE: Some lens opacity and rapid breathing ( difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some dysplasia. ; RIGHT EYE: Hyaloid present.

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; LEFT EYE: Difficult to image and focus (corneal opacity).,
Ophthalmoscope Observation: Both eyes slight rd8.; RIGHT EYE: Some dysplasia. Lesion (abnormal pigmentation) on retina. Blood vessel slightly early branching

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).; LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); LEFT EYE: Slight rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (very difficult to image and focus); RIGHT EYE: Small bright spot/lesion (mid right).

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity ; LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8 some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present, moderate rd8, slight lens opacity

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; LEFT EYE: Hyaloid present. Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight lens opacity.; RIGHT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE: White cotton patches/large dysplasia.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8; LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, some rd8

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate rd8.; RIGHT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes moderate rd8.; LEFT EYE:

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity. ; RIGHT EYE: Some dysplasia.

58 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus ; RIGHT EYE: Some rd8

57 weeks old

Tmem74em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.; LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and some dysplasia. Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia.

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