Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris (obstruct part of retina), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity and some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity and some rd8 ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Restless mouse (difficult to image).; RIGHT EYE: Slight rd8 and hemorrhaging.

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, crystallized debris, slight rd8

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity,slight dysplasia ; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, slight dysplasia; RIGHT EYE: Small lesion/depigmentation on retina

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging. ; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; LEFT EYE: Hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8 and white cotton debris (difficult to focus and obstruct part of retina).; RIGHT EYE: Early vessel branching (top left). Slight hemorrhaging.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8.; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight rd8 and some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight rd8, some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus and image), some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia.

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8/dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8, some dysplasia; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia; LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, severe rd8 and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, slight rd8/dysplasia

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight hemorrhaging, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Slight dysplasia, some rd8

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

58 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes slight dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; LEFT EYE: Some rd8 an lens opacity ( difficult to image and focus).,
Ophthalmoscope Observation: Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; RIGHT EYE: Difficult to focus, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8 ; LEFT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to focus), slight rd8, slight dysplasia, slight hemorrhaging.; RIGHT EYE:

57 weeks old

Slc30a4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; LEFT EYE: White cotton debris (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ; RIGHT EYE: Slightly early vessel branching (mid right and bottom).

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