Gross Pathology and Tissue Collection: Images
WT Images
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
15 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
15 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Mutant Images
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; eye - abnormal eye morphology, right eye white; seminal vesicles - abnormal seminal vesicle morphology, left seminal vesicle is red/brown; stomach - enlarged stomach, area=20x13, large stomach,
Comments (in English): Lateral view,
Comments (in English): Internal view of enlarged stomach,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; ovary - abnormal ovary morphology, small white masses on ovaries,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; ovary - abnormal ovary morphology, small white masses on ovaries,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; ovary - abnormal ovary morphology, small white masses on ovaries,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; eye - abnormal eye morphology, right eye white; seminal vesicles - abnormal seminal vesicle morphology, left seminal vesicle is red/brown; stomach - enlarged stomach, area=20x13, large stomach,
Comments (in English): Lateral view,
Comments (in English): Internal view of enlarged stomach,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.
Hairless patch on thorax between forearms (12x9mm); The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes 4mm; thymus - normal, detached from pluck during necropsy,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.
Hairless patch on thorax between forearms (12x9mm); The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes 4mm; thymus - normal, detached from pluck during necropsy,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; eye - abnormal eye morphology, right eye white; seminal vesicles - abnormal seminal vesicle morphology, left seminal vesicle is red/brown; stomach - enlarged stomach, area=20x13, large stomach,
Comments (in English): Lateral view,
Comments (in English): Internal view of enlarged stomach,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.
Hairless patch on thorax between forearms (12x9mm); The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes 4mm; thymus - normal, detached from pluck during necropsy,
Comments (in English): Internal view
16 weeks old
Tmem8bem1(IMPC)Tcp heterozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.
Hairless patch on thorax between forearms (12x9mm); The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; sternum - abnormal sternum ossification, length=4, xyphoid process protrudes 4mm; thymus - normal, detached from pluck during necropsy,
Comments (in English): Internal view
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