Eye Morphology: Images Slit Lamp

WT Images

14 weeks old

Slit Lamp observation: Mild opacity over right pupil,
Slit Lamp observation: Mild opacity over right pupil; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Mild opacity over left pupil,
Slit Lamp observation: Mild opacity over left pupil; LEFT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye,
Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye; LEFT EYE: magnification = 25x,
Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye; RIGHT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Small left pupil; Dark spots in left iris,
Slit Lamp observation: Small left pupil; Dark spots in left iris; LEFT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape,
Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; LEFT EYE: magnification = 40x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Multiple holes in left and right iris, around pupil,
Slit Lamp observation: Multiple holes in left and right iris, around pupil; LEFT EYE: magnification = 16x,
Slit Lamp observation: Multiple holes in left and right iris, around pupil; RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Left pupil eccentric,
Slit Lamp observation: Left pupil eccentric; LEFT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Multiple holes in left and right iris, around pupil,
Slit Lamp observation: Multiple holes in left and right iris, around pupil; LEFT EYE: magnification = 16x,
Slit Lamp observation: Multiple holes in left and right iris, around pupil; RIGHT EYE: magnification = 16x

15 weeks old

Slit Lamp observation: RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye,
Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye; LEFT EYE: magnification = 25x,
Slit Lamp observation: Right pupil slightly irregularly shaped; Cataract in left eye; RIGHT EYE: magnification = 25x

15 weeks old

Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape,
Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape; LEFT EYE: magnification = 16x,
Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape; RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; LEFT EYE: magnification = 40x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 40x

15 weeks old

Slit Lamp observation: Large hole in right iris,
Slit Lamp observation: Large hole in right iris; RIGHT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Cataract over left pupil,
Slit Lamp observation: Cataract over left pupil; LEFT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Severe opacity on right cornea,
Slit Lamp observation: Severe opacity on right cornea; RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Severe opacity in left eye, pupil not seen,
Slit Lamp observation: Severe opacity in left eye, pupil not seen; LEFT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Mild cataract in left eye,
Slit Lamp observation: Mild cataract in left eye; LEFT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Small cataract in left pupil,
Slit Lamp observation: Small cataract in left pupil; LEFT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Minor opacity in left cornea,
Slit Lamp observation: Minor opacity in left cornea; LEFT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Small hole in right iris to right of pupil,
Slit Lamp observation: Small hole in right iris to right of pupil; RIGHT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens,
Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Left pupil eccentric, located higher, oval shape,
Slit Lamp observation: Left pupil eccentric, located higher, oval shape; LEFT EYE: magnification = 16x

15 weeks old

Slit Lamp observation: Hole in right iris,
Slit Lamp observation: Hole in right iris; RIGHT EYE: magnification = 25x

15 weeks old

Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape,
Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape; LEFT EYE: magnification = 16x,
Slit Lamp observation: Opacity on right and left cornea; right pupil eccentric and elongated, left pupil abnormal shape; RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; LEFT EYE: magnification = 40x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity in right cornea, pupil not seen, reduced curvature; Opacity in left pupil; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Right pupil slightly irregular in shape,
Slit Lamp observation: Right pupil slightly irregular in shape; RIGHT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape,
Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity on right cornea; right pupil abnormal shape; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Eccentric right pupil,
Slit Lamp observation: Eccentric right pupil; RIGHT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Corneal opacity in right eye, completely covered,
Slit Lamp observation: Corneal opacity in right eye, completely covered; RIGHT EYE: magnification = 25x

14 weeks old

Slit Lamp observation: Left pupil off centre, situated higher; Left pupil irregularly shaped and oval; Left pupil less responsive to light,
Slit Lamp observation: Left pupil off centre, situated higher; Left pupil irregularly shaped and oval; Left pupil less responsive to light; LEFT EYE: magnification = 40x

14 weeks old

Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens,
Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens; RIGHT EYE: magnification = 16x,
Slit Lamp observation: Severe opacity in right cornea, haemorrhage on cornea, small right eye; mild opacity on left lens; RIGHT EYE: magnification = 40x

15 weeks old

Slit Lamp observation: Smaller left iris, irregularly shaped, sclera more visible,
Slit Lamp observation: Smaller left iris, irregularly shaped, sclera more visible; LEFT EYE: magnification = 16x

14 weeks old

Slit Lamp observation: Irregularly shaped iris, smaller; Sclera is more visible and whiter in colour,
Slit Lamp observation: Irregularly shaped iris, smaller; Sclera is more visible and whiter in colour; RIGHT EYE: magnification = 40x

Mutant Images

14 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry,
Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry; LEFT EYE: magnification = 25x,
Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry; RIGHT EYE: magnification = 25x

14 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry,
Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry; LEFT EYE: magnification = 25x,
Slit Lamp observation: Large vein visible in right iris; Left corneal surface grainy, dry; RIGHT EYE: magnification = 25x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Holes in right iris,
Slit Lamp observation: Holes in right iris; RIGHT EYE: magnification = 25x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Left iris small, irregularly shaped; Left pupil irregularly shaped,
Slit Lamp observation: Left iris small, irregularly shaped; Left pupil irregularly shaped; LEFT EYE: magnification = 16x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Left pupil slightly irregularly shaped,
Slit Lamp observation: Left pupil slightly irregularly shaped; LEFT EYE: magnification = 25x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Severe cataract in right eye; Small right eye, eyelid unable to fully open,
Slit Lamp observation: Severe cataract in right eye; Small right eye, eyelid unable to fully open; RIGHT EYE: magnification = 25x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Severe opacity in right eye, pupil not seen,
Slit Lamp observation: Severe opacity in right eye, pupil not seen; RIGHT EYE: magnification = 16x

14 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Left eye dry, gummy buildup,
Slit Lamp observation: Left eye dry, gummy buildup; LEFT EYE: magnification = 25x

15 weeks old

Cox4i1tm1.1(KOMP)Vlcg heterozygote

Slit Lamp observation: Large cataract over right pupil,
Slit Lamp observation: Large cataract over right pupil; RIGHT EYE: magnification = 25x

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