Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present ; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small crystallized debris present

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity, crystallized debris, early branching blood vessel near optic nerve

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; LEFT EYE: Some hemorrhage, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity; RIGHT EYE: Small lesions, slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity, slight dysplasia,crystallized debris

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloids present (various sizes),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches ; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Hyaloid present, some dysplasia, some rd8, slight molten patches

14 weeks old

Tmem8bem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Crystallized debris present, slight dysplasia

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage, some very bright dysplasia; RIGHT EYE: Small lesions

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Crystallized debris, hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE: Small hyaloids present, crystallized debris. Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very slight lens opacity and displasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Large lesion, some dysplasia, slight lens opacity slight hemorrhage

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

Tmem8bem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight molten patches ; RIGHT EYE: Hyaloid present, slight hemorrhage, slight molten patches

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