Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; LEFT EYE: Slight hemorrhaging, dysplasia and slightly early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity ; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some debris (difficult to image and focus). Early vessel branching and crossing

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; LEFT EYE: Slight lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia, hemorrhaging; RIGHT EYE: Some lens opacity, slightly early blood vessel branching

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; RIGHT EYE: Small crystallized debris, small abnormal pigmentations patch,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight hemorrhage, slight dysplasia; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, hemorrhaging and slight dysplasia, early vessel branching ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; LEFT EYE: Slightly early blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, multiple small hyaloid present ; RIGHT EYE: Crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight dysplasia, slight lens opacity, slight rd8,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some debris (difficult to focus), some lens opacity. Early blood vessel branching, some rd8

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present, corneal opacity and crystallized debris (difficult to image and focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel slightly early branching, very slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, very slight hemorrhage; RIGHT EYE: Blood vessel early branching, slight dysplasia, a small lesion on retina

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; LEFT EYE: Some lens opacity and debris (difficult to focus). Early vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia. ; RIGHT EYE: Slight lens opacity

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; RIGHT EYE: Some debris (difficult to focus), blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia, hemorrhaging and lens opacity.; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches; LEFT EYE: Slight lens opacity, small crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; RIGHT EYE: Some lens opacity (difficult to focus), small hyaloid, some molten patches,
Ophthalmoscope Observation: Both eyes blood vessel early branching, some rd8, some dysplasia; LEFT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Abnormal blood vessel branching into different layers (vessel shaking), blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Wavy vessels?! Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Crystallized debris (difficult to focus).

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Katnal1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; LEFT EYE: Some hemorrhaging, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, dysplasia; RIGHT EYE: Some debris (difficult to focus). Some lens opacity, Slight hemorrhaging

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter