Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes uneven vessel thickness (very thin); slight dysplasia and lens opacity (difficutl to focus).; RIGHT EYE: Crystallized debris. Moderate rd8

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8, slight dysplasia ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; LEFT EYE: Blood vessel uneven thickness,
Ophthalmoscope Observation: Both eyes moderate rd8 and some hemorrhaging, slight lens opacity. Blood vessel early branching.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina); LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some corneal opacity, massive hyaloid and small crystallized debris (obstructing the optic disc), blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Narrow eye opening, slight corneal opacity, hyaloid and big crystallized debris (obstructing part of retina)

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity (difficult to focus). Small lesion?

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia ; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; LEFT EYE: Some dysplasia, blood vessel crossing,
Ophthalmoscope Observation: Both eyes several early vessel branching, some rd8 and slight lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, very slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, small crystallized debris

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; LEFT EYE: Slight lens opacity, small hyaloid, blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, very slight molten patches ; RIGHT EYE: Some lens opacity, slight dysplasia

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia ; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; LEFT EYE: Blood vessel slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity; RIGHT EYE: Some dysplasia

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

15 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; LEFT EYE: Some debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity.; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Ints8em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage, very slight molten patches ; RIGHT EYE: Slight lens opacity. Bright crystallized debris. Blood vessel early branching

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