Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data; LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; LEFT EYE: Lens opacity/cataract, difficult to focus. Small lesions and some rd8,
Ophthalmoscope Observation: Both eyes have hyaloid ; RIGHT EYE: Massive hyaloid, unable to image and focus

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina ; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Small white patches on retina

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; LEFT EYE: Slight molten patch,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, small white lesion/patch on retina; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Right eye closed ; LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity difficult to focus, some rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Right eye closed

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 dysplasia lesions.,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; RIGHT EYE: Slight opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes some rd8 dysplasia and hemorrhaging.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus, some rd8; RIGHT EYE: Some dysplasia, slight hemorrhage

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; RIGHT EYE: Crystallized debris difficult to focus, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging ; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus). Blood vessel slightly early branching. Very slight molten patches, small lesion

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data; LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE: Some bright dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; LEFT EYE: Slight opacity,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia and hemorrhaging.; RIGHT EYE: Small white patch/lesion.

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data; LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: LEFT EYE: Severe Corneal and lens opacity/cataract difficult to focus and image,
Ophthalmoscope Observation: RIGHT EYE: Abnormal eye, no data

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; RIGHT EYE: Some rd8 dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and. hemorrhaging opacity (difficult to focus).; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image ; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some corneal opacity difficult to focus, and image

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE: Some dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:

14 weeks old

Atp8b1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia. ; RIGHT EYE: Hyaloid present. Dark circle around optic disk.

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