Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight rd8, dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; LEFT EYE: Bright crystallized debris (obstructing the retina), slight hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small hyaloid, blood vessel slightly early branching. some rd8; RIGHT EYE: Crystallized debris, some hemorrhage, slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel early branching, slight rd8, some dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; LEFT EYE: Tiny hyaloid, abnormal blood vessel branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage, lesion present; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, slight rd8, slight dysplasia. Blood vessel early branching.; LEFT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present. Slight dysplasia

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid and crystallized debris. Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Multiple tiny hyaloid. Abnormal retinal pigmentation near optic disc

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; LEFT EYE: Tiny hyaloid. Blood vessel crossing and slightly early branching. Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Slight rd8; RIGHT EYE: Blood vessel early branching. Some dysplasia, some hemorrhage

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Crystallized debris, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, blood vessel early branching, some rd8, slight dysplasia, slight hemorrhage, small lesion/bright dysplasia on retina; RIGHT EYE:

14 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus); LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus). Small crystallized debris. Blood vessel early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity. Hyaloid and crystallized debris (difficult to focus)

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; LEFT EYE: Small lesion present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some hemorrhage, slight dysplasia, slight rd8 ; RIGHT EYE: Hyaloid present, blood vessel crossing

15 weeks old

Fndc3aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8 ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; LEFT EYE: Multiple small hyaloid, slight rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some dysplasia, slight hemorrhage ; RIGHT EYE: Some rd8

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