Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina; LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina; LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data; LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina; LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina; LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight lens opacity,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data; LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data; LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data; LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, retina no data

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate dysplasia ; RIGHT EYE: Some lens opacity, crystallized debris

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8; LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to focus), moderate rd8, slightly dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Difficult to focus and image due to corneal opacity/cataract, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus); LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8. Some lens opacity (difficult to focus)

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity (difficult to focus),
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Very slight corneal opacity, crystallized debris, some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing ; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Slight corneal opacity, moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Tiny hyaloid, some rd8, early blood vessel branching and crossing

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; LEFT EYE: Difficult to focus and image due to slight lens opacity. Small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia ; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; LEFT EYE: Slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight corneal opacity ; RIGHT EYE: Small cataract, some dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; LEFT EYE: A small hyaloid present.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight dysplasia; RIGHT EYE: Some rd8

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus) and slight rd8.; RIGHT EYE:

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; LEFT EYE: Slight lens opacity, hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some dysplasia ; RIGHT EYE: Some lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some lesions present

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present. Slight rd8 and lens opacity.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.; LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens and corneal opacity (difficult to image and focus). Moderate rd8.,
Ophthalmoscope Observation: RIGHT EYE: Specks of hyaloid present. White cotton debris (difficult to image). Slight rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; LEFT EYE: Crystallized debris present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Slight hemorrhaging.; RIGHT EYE: Lesion present on retina

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight corneal opacity, very slight lens opacity

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE:

58 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE: Severe rd8 and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Some rd8.

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; LEFT EYE: Slight dysplasia and some lens opacity (difficult to I and focus).,
Ophthalmoscope Observation: Both eyes some rd8. Restless mouse.; RIGHT EYE: Slight lens opacity (difficult to focus).

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Crystallized debris, hyaloid present; RIGHT EYE: Some lens opacity, small cataract, some rd8, slight dysplasia

57 weeks old

Tenm4em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Slight corneal opacity

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