Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.; LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.; LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data; LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.; LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data; LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data; LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity, severe rd8/dysplasia; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data; LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage ; LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Corneal and slight lens opacity difficult to focus, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some lens opacity, difficult to focus, some hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data; LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present, slight lens opacity, difficult to focus and image, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract, retina no data

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia.; RIGHT EYE: Hyaloid present. Slight lens opacity.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight corneal opacity, some lens opacity. Massive hyaloid present (slight retinal obstruction), crystallized debris, blood vessel slightly early branching, severe rd8/dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; LEFT EYE: Slight lens opacity, moderate dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present ; RIGHT EYE: Some lens opacity, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; LEFT EYE: Slight corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, some rd8, slight dysplasia; RIGHT EYE: Large hyaloid obstructing the optic nerve, difficult to focus and image. Lesion/abnormal retinal pigmentations, blood vessel early branching and abnormal placement

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.; LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Vessel crossing and some dysplasia. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; no data.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; LEFT EYE: Small hyaloid present. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, slight hemorrhaging and lens opacity. Blood vessel early branching; RIGHT EYE: Some debris (difficult to focus).

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, hyaloid present, blood vessel crossing, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight corneal opacity, blood vessel slightly early branching, slight rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), small crystallized debris

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Hyaloid present, (difficult to focus),
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; LEFT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; LEFT EYE: Moderate rd8. Some crystalline deposits.,
Ophthalmoscope Observation: Both eyes hyaloid present. Some lens opacity (difficult to focus).; RIGHT EYE: Severe rd8.

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, slight rd8, some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, moderate dysplasia, slight hemorrhage

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; LEFT EYE: Some rd8. Blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes small hyaloid present (and some debris), slight lens opacity (difficult to focus).; RIGHT EYE: Slight rd8, some dysplasia. Blood vessel slightly early branching

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Slight corneal opacity, massive hyaloid (obstructing the optic nerve), blood vessel early branching, severe dysplasia

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present, blood vessel slightly early branching, slight dysplasia, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Small eye opening, eccentric pupil and corneal opacity on pupil (unable to image), no data retina

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present. Some rd8, dysplasia and lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage, slight opacity difficult to focus ; RIGHT EYE:

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; LEFT EYE: Some lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes blood vessel early branching; RIGHT EYE: Slight lens opacity, small hyaloid present, some dysplasia

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; LEFT EYE: Hyaloid present, some rd8,,
Ophthalmoscope Observation: Both eyes slight corneal opacity, some lens opacity, slight hemorrhage; RIGHT EYE: Difficult to focus. Multiple tiny hyaloid, blood vessel slightly early branching, slight rd8

58 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; LEFT EYE: Slight corneal opacity. Crystallized debris, blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, hyaloid present, blood vessel early branching, severe rd8; RIGHT EYE:

57 weeks old

Klhl12em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; LEFT EYE: Hyaloid present. Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight corneal opacity, slight lens opacity, severe rd8; RIGHT EYE: Massive hyaloid present (obstructing the optic nerve and part of retina). Blood vessel weird branching

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