Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus; LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus; LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8; LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8; LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8; LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus; LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8; LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Severe dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Moderate rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; RIGHT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 an dysplasia. ; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8, and slight lens opacity; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus; LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Small lesion/white patch bottom right of retina,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8; LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: LEFT EYE: Severe corneal/lens opacity, no data collected,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present and some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 ; LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight opacity, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Lesion/patch bottom of retina and severe rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight opacity on lens; RIGHT EYE:

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus; LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Severe rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and slight hemorrhage, hard to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

57 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8; RIGHT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes moderate rd8; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some lens opacity and difficult to focus. Moderate rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging and crystalline deposits on the lens (some retinal obstruction).,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus. Some patches/lesions,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Lens opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lesion below optic nerve, some rd8,
Ophthalmoscope Observation: LEFT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity difficult to focus and some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous; LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and dysplasia, hard to focus,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, some crystalline stuff in vitreous

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus; LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: LEFT EYE: Eye partially closed, white eye, unable to take pictures,
Ophthalmoscope Observation: RIGHT EYE: Opacity, difficult to focus

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; LEFT EYE:,
Ophthalmoscope Observation: Restless mouse (difficult to image). Both eyes some rd8 and dysplasia.; RIGHT EYE:

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight dysplasia

58 weeks old

Vps33aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8 and dysplasia, hard to focus

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