Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; LEFT EYE: Some hemorrhage, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight corneal and lens opacity difficult to focus and image ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; LEFT EYE: Corneal opacity,,
Ophthalmoscope Observation: Both eyes some dysplasia. Restless mouse, difficult to image; RIGHT EYE: Slight lens opacity, some dysplasia

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia ; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; LEFT EYE: Moderate rd8, corneal opacity Difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity; RIGHT EYE: Some rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes some corneal opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present. Cataract present. Slight hemorrhaging.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, extremely thin blood vessel. Abnormal retinal surface above optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus and image). Moderate rd8, some dysplasia; LEFT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; LEFT EYE: Some rd8, darker blood vessels, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens and corneal opacity, some dysplasia ; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus); LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; LEFT EYE: Very slight corneal opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes severe rd8, slight lens opacity ; RIGHT EYE: Slight corneal opacity on pupil (difficult to focus)

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; LEFT EYE: Some rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity difficult to focus ; RIGHT EYE: Moderate rd8

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Some dysplasia, lesion/pigmentation near optic nerve

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; LEFT EYE: Lesion presents,
Ophthalmoscope Observation: Both eyes some dysplasia, slight lens opacity ; RIGHT EYE:

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present over optic disk (some obstruction). Slight hemorrhaging.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity. ; LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); LEFT EYE: Some lens opacity.,
Ophthalmoscope Observation: Both eyes severe rd8. Restless mouse, (difficult to focus and image); RIGHT EYE: Hyaloid and crystallized deposits present. Slight lens opacity.

58 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; LEFT EYE: Slight hemorrhaging, slight depigmentation/lesion,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus and image. Some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; LEFT EYE: Hyaloid present. Restless mouse,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8; RIGHT EYE:

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8. ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; LEFT EYE: Moderate rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity difficult to focus ; RIGHT EYE: Some rd8.

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight lens opacity

57 weeks old

Hdgfl3em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; LEFT EYE: Some rd8, corneal opacity,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia ; RIGHT EYE: Hyaloid present

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