Spleen Immunophenotyping: Images associated with FACS analysis
WT Images
15 weeks old
Mature NK cells - % of NK cellls: 79.014
15 weeks old
Resting Treg cells - % of Treg: 58.223
15 weeks old
Conventional DC (cDC) - % of CD45+: 1.509
15 weeks old
Resting CD4- NKT cells - % of CD4- NKT cells: 65.42
15 weeks old
CD11b-low cDC - % of cDC: 44.004
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD45+: 0.16
15 weeks old
Effector gd cells - % of CD45+: 0.504
15 weeks old
Immature NK cells - % of lymphocytes: 0.621
15 weeks old
Total CD4- NKT cells - % of CD45+: 0.33
15 weeks old
CD4+ T helper cells - % of CD4+: 88.702
15 weeks old
B1a cells - % of B cells: 1.383
15 weeks old
Germinal centre B cells - % of CD45+: 0.24
15 weeks old
Marginal zone B cells - % of B2 cells: 6.071
15 weeks old
CD11b-low cDC - % of CD45+: 0.664
15 weeks old
Macrophages - % of CD45+: 0.616
15 weeks old
Effector Treg cells - % of CD45+: 0.617
15 weeks old
Effector CD8+ T cells - % of CD8+: 6.136
15 weeks old
Ly6C+ NKT cells - % of lymphocytes: 0.53
15 weeks old
Mature NK cells - % of lymphocytes: 2.337
15 weeks old
Naive CD8+ T cells - % of CD45+: 5.623
15 weeks old
Plasma cells - % of CD45+: 0.106
15 weeks old
Effector NK cells - % of CD45+: 0.361
15 weeks old
B2 t1 + t2 cells - % of B2 cells: 9.78
15 weeks old
Resting CD4+ T helper cells - % of CD4+ T helper cells: 70.523
15 weeks old
KLRG1+ Treg cells - % of CD45+: 0.131
15 weeks old
CD5+ gd T cells - % of CD45+: 0.499
15 weeks old
Effector CD4- NKT cells - % of CD4- NKT cells: 34.58
15 weeks old
CD11b-high cDC - % of CD45+: 0.84
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 1.394
15 weeks old
Total ab T cells - % of CD45+: 22.716
15 weeks old
Effector CD8+ T cells - % of CD45+: 0.591
15 weeks old
Effector CD4+ T helper cells - % of CD45+: 3.361
15 weeks old
Total gd T cells - % of CD45+: 1.223
15 weeks old
Plasma cells - % of B2 cells: 0.169
15 weeks old
Resting CD4+ NKT cells - % of CD4+ NKT cells: 16.46
15 weeks old
Plasmacytoid DC - % of DC: 19.041
15 weeks old
Total CD4+ T cells - % of CD45+: 12.97
15 weeks old
Effector gd T cells - % of gd T cells: 41.226
15 weeks old
Resting CD8+ T cells - % of CD45+: 3.147
15 weeks old
Total CD8+ T cells - % of ab T cells: 42.423
15 weeks old
Effector CD4+ NKT cells - % of CD45+: 0.268
15 weeks old
Marginal zone precursor B cells - % of CD45+: 2.948
15 weeks old
CD103+ CD11b-low cDC - % of CD45+: 0.064
15 weeks old
Resting CD8+ T cells - % of CD8+: 32.653
15 weeks old
Total B2 cells - % of B cells: 98.617
15 weeks old
Resting NK cells - % of CD45+: 2.079
15 weeks old
Total CD4+ T cells - % of ab T cells: 57.099
15 weeks old
Total Treg cells - % of CD45+: 1.486
15 weeks old
Immature NK cells - % of NK cells: 20.986
15 weeks old
Ly6C+ immature NK cells - % of lymphocytes: 0.09
Mutant Images
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ NKT cells - % of NKT cells: 71.418
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 60.753
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 53.256
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ Treg cells - % of Treg: 14.397
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 36.853
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 33.352
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.581
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 7.895
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ Treg cells - % of Treg: 15.25
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ NKT cells - % of NKT cells: 67.105
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of CD45+: 1.31
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 89.574
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 46.744
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 56.694
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 34.394
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.633
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 83.085
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ immature NK cells - % of lymphocytes: 0.101
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 38.747
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of CD45+: 1.417
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ NKT cells - % of NKT cells: 57.401
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD4+ NKT cells - % of CD4+ NKT cells: 23.193
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 16.915
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of CD45+: 1.238
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of B2 cells: 2.309
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD4+ NKT cells - % of CD4+ NKT cells: 28.66
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ immature NK cells - % of lymphocytes: 0.099
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of B2 cells: 1.829
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.354
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 81.96
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD4+ NKT cells - % of CD4+ NKT cells: 68.799
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ NK cells - % of NK cells: 64.175
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 18.04
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 1.858
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.894
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.557
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 65.606
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.606
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 60.734
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 8.698
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 1.471
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 10.426
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.575
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.437
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 43.306
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ NK cells - % of NK cells: 48.438
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ immature NK cells - % of lymphocytes: 0.103
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 11.417
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ Treg cells - % of Treg: 12.648
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ NK cells - % of NK cells: 67.646
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 38.783
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of CD45+: 1.112
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ NK cells - % of NK cells: 60.999
15 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 1.937
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of B2 cells: 2.495
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 88.583
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ immature NK cells - % of lymphocytes: 0.107
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 7.344
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Resting CD4+ NKT cells - % of CD4+ NKT cells: 45.688
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Marginal zone B cells - % of B2 cells: 2.265
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
KLRG1+ Treg cells - % of Treg: 12.9
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Ly6C+ NKT cells - % of NKT cells: 61.836
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 63.147
16 weeks old
Arhgef1tm1a(EUCOMM)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 66.114
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