Spleen Immunophenotyping: Images associated with FACS analysis
WT Images
15 weeks old
Mature NK cells - % of NK cellls: 79.014
15 weeks old
Resting Treg cells - % of Treg: 58.223
15 weeks old
Conventional DC (cDC) - % of CD45+: 1.509
15 weeks old
Resting CD4- NKT cells - % of CD4- NKT cells: 65.42
15 weeks old
CD11b-low cDC - % of cDC: 44.004
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD45+: 0.16
15 weeks old
Effector gd cells - % of CD45+: 0.504
15 weeks old
Immature NK cells - % of lymphocytes: 0.621
15 weeks old
Total CD4- NKT cells - % of CD45+: 0.33
15 weeks old
CD4+ T helper cells - % of CD4+: 88.702
15 weeks old
B1a cells - % of B cells: 1.383
15 weeks old
Germinal centre B cells - % of CD45+: 0.24
15 weeks old
Marginal zone B cells - % of B2 cells: 6.071
15 weeks old
CD11b-low cDC - % of CD45+: 0.664
15 weeks old
Macrophages - % of CD45+: 0.616
15 weeks old
Effector Treg cells - % of CD45+: 0.617
15 weeks old
Effector CD8+ T cells - % of CD8+: 6.136
15 weeks old
Ly6C+ NKT cells - % of lymphocytes: 0.53
15 weeks old
Mature NK cells - % of lymphocytes: 2.337
15 weeks old
Naive CD8+ T cells - % of CD45+: 5.623
15 weeks old
Plasma cells - % of CD45+: 0.106
15 weeks old
Effector NK cells - % of CD45+: 0.361
15 weeks old
B2 t1 + t2 cells - % of B2 cells: 9.78
15 weeks old
Resting CD4+ T helper cells - % of CD4+ T helper cells: 70.523
15 weeks old
KLRG1+ Treg cells - % of CD45+: 0.131
15 weeks old
CD5+ gd T cells - % of CD45+: 0.499
15 weeks old
Effector CD4- NKT cells - % of CD4- NKT cells: 34.58
15 weeks old
CD11b-high cDC - % of CD45+: 0.84
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 1.394
15 weeks old
Total ab T cells - % of CD45+: 22.716
15 weeks old
Effector CD8+ T cells - % of CD45+: 0.591
15 weeks old
Effector CD4+ T helper cells - % of CD45+: 3.361
15 weeks old
Total gd T cells - % of CD45+: 1.223
15 weeks old
Plasma cells - % of B2 cells: 0.169
15 weeks old
Resting CD4+ NKT cells - % of CD4+ NKT cells: 16.46
15 weeks old
Plasmacytoid DC - % of DC: 19.041
15 weeks old
Total CD4+ T cells - % of CD45+: 12.97
15 weeks old
Effector gd T cells - % of gd T cells: 41.226
15 weeks old
Resting CD8+ T cells - % of CD45+: 3.147
15 weeks old
Total CD8+ T cells - % of ab T cells: 42.423
15 weeks old
Effector CD4+ NKT cells - % of CD45+: 0.268
15 weeks old
Marginal zone precursor B cells - % of CD45+: 2.948
15 weeks old
CD103+ CD11b-low cDC - % of CD45+: 0.064
15 weeks old
Resting CD8+ T cells - % of CD8+: 32.653
15 weeks old
Total B2 cells - % of B cells: 98.617
15 weeks old
Resting NK cells - % of CD45+: 2.079
15 weeks old
Total CD4+ T cells - % of ab T cells: 57.099
15 weeks old
Total Treg cells - % of CD45+: 1.486
15 weeks old
Immature NK cells - % of NK cells: 20.986
15 weeks old
Ly6C+ immature NK cells - % of lymphocytes: 0.09
Mutant Images
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 38.43
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.567
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 41.82
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.448
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 0.782
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 12.611
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 78.466
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 9.723
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 54.179
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 3.098
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 35.726
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 63.491
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 75.874
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.729
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 19.697
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 36.388
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 59.508
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 2.437
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 32.965
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 73.409
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 41.668
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.103
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 0.654
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.457
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 57.591
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.691
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 38.338
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 1.981
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 11.704
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 0.741
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 11.787
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 40.109
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.329
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 1.876
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 11.531
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 16.067
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 11.247
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 21.455
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 38.715
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.055
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 4.102
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 23.964
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 1.022
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.488
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 65.881
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 25.569
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 59.713
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 1.053
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.446
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 3.072
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ T helper cells - % of CD4+ T helper cells: 26.447
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 41.419
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 1.075
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 9.12
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd T cells - % of gd T cells: 43.323
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 2.537
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 40.837
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of CD45+: 11.081
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 2.107
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 41.146
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Eosinophils - % of CD45+: 1.247
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 2.279
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD8+ T cells - % of CD45+: 2.719
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 80.299
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
CD103+ CD11b-low cDC - % of CD11b-low cDC: 37.752
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Total CD8+ T cells - % of ab T cells: 42.277
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting gd T cells - % of gd T cells: 62.053
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector gd cells - % of CD45+: 0.638
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 1.391
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting NK cells - % of CD45+: 2.411
16 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Effector CD4+ NKT cells - % of CD45+: 0.343
15 weeks old
Cxcr2tm1a(EUCOMM)Wtsi heterozygote
Resting CD4+ T helper cells - % of CD4+ T helper cells: 60.888
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