Gross Pathology and Tissue Collection: Images
WT Images
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
15 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
15 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Mutant Images
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; lymph nodes - enlarged lymph nodes, area=3x2, salivary gland region,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; large intestine - black content in cecum,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; large intestine - black content in cecum,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): There are some alopecia around eyes (R: 5x2mm, L: 9x5mm)
Animal was bright, alert and responsive. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ,
Comments (in English): Lateral view,
Comments (in English): Internal view,
Comments (in English): liver; Internal view of lesion on right mudial lobe; dark red lesion on right medial lobe; area=4x1
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): There are some alopecia around eyes (R: 5x2mm, L: 9x5mm)
Animal was bright, alert and responsive. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ,
Comments (in English): Lateral view,
Comments (in English): Internal view,
Comments (in English): liver; Internal view of lesion on right mudial lobe; dark red lesion on right medial lobe; area=4x1
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ; lymph nodes - enlarged lymph nodes, area=3x2, salivary gland region,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
Aspscr1em1(IMPC)Tcp homozygote
Liver: PATO:0001323,
Liver: MP:0000598,
Liver: PATO:0000627,
Liver: PATO:0000322,
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin. ,
Comments (in English): Lateral view,
Comments (in English): Internal view,
Comments (in English): liver; Internal view of lesion on right mudial lobe; dark red lesion on right medial lobe; area=4x1
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