Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, slight dysplasia ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity , some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia ; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; LEFT EYE: Tiny hyaloid. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Blood vessel early branching. Some rd8; RIGHT EYE: Some dysplasia

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; RIGHT EYE: Multiple blood vessel early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and dysplasia ; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Slight lens opacity. Crystallized debris

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Some rd8, moderate dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Severe rd8 and some dysplasia, some hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve); LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; LEFT EYE: Slight rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage ; RIGHT EYE: Some rd8, blood vessel very early crossing (near optic nerve)

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; LEFT EYE: Very slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Hyaloid and crystallized debris present. Some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia. Abnormal retinal pigmentation

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; LEFT EYE: Slight lens opacity. Crystallized debris,
Ophthalmoscope Observation: Both eyes blood vessel early branching. Some rd8; RIGHT EYE: Very slight lens opacity. Slight dysplasia, slight hemorrhage

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8; RIGHT EYE: Crystallized debris (difficult to focus), tiny hyaloid

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; RIGHT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, small lesion on retina; LEFT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Some debris, slight molten patches,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Blood vessel early branching (mid top and bottom) and crossing.

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; LEFT EYE: Small hyaloids present. Slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity. Bright crystallized debris (difficult to focus). Some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Scfd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE:

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