Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia ; LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia ; LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia ; LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia ; LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; LEFT EYE: Blood vessel crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, blood vessel early branching

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity ; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; LEFT EYE: Corneal and lens opacity (difficult to image).,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8.; RIGHT EYE: Slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Slight early blood vessel branching. Slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia ; LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: LEFT EYE: Severe corneal opacity, no retina data,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, crystallized debris, some rd8, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, slightly early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, small lesion below optic nerve

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity, hyaloid and crystallized debris present,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; LEFT EYE: Slight lens opacity, slight dysplasia,
Ophthalmoscope Observation: Both eyes crystallized debris. Some rd8; RIGHT EYE: Some lens opacity, blood vessel crossing and slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; LEFT EYE: Slight dysplasia, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8; RIGHT EYE: Difficult to focus. Blood vessel slightly early branching. Slight hemorrhage

15 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Big hyaloid present (obstruct part of retina, difficult to focus and image), enlarged optic nerve

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity ; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity, blood vessel early branching and crossing. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Very slight lens opacity

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging. Slight lens opacity (difficult to focus).; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE: Crystallized debris (difficult to focus), slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, small crystallized debris, some rd8. Blood vessel crossing; RIGHT EYE: Small hyaloid and crystallized debris present, some dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, hyaloid present

14 weeks old

Mfsd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Corneal opacity, massive hyaloid present, (difficult to focus and obstructing the optic nerve), slightly early blood vessel branching, some molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, crystallized debris, early blood vessel branching, slight dysplasia

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE:

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

15 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Lesion present, slight molten patches,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Tiny hyaloid, slight dysplasia, very slight hemorrhage

14 weeks old

Mfsd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE: Slight hemorrhage, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE:

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