Histopathology data for Uba2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HET F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #4 Eye with optic nerve normal [MPATH:458] 0 0
HET F #3 Liver [MA:0000358] lipid deposition [MPATH:42] 1 0 multi-localised Hepatic lipidosis
HET M #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #4 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 steatosis MPATH:622 multifocal to coalescing Hepatic lipidosis
HET F #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET F #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #2 Thyroid normal [MPATH:458] 0 0
HET F #4 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET F #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET F #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Testes normal [MPATH:458] 0 0
HET M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET F #3 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 distributed Lymphoid hyperplasia
HET M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #4 Thyroid normal [MPATH:458] 0 0
HET M #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #1 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 multi-localised Moderate neutrophilic gastritis.
HET M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET F #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #3 Eye with optic nerve normal [MPATH:458] 0 0
HET M #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET M #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HET M #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #2 Testes normal [MPATH:458] 0 0
HET F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #2 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET M #2 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 multi-localised Moderate neutrophilic gastritis.
HET M #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #2 Eye with optic nerve normal [MPATH:458] 0 0
HET M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #2 Prostate normal [MPATH:458] 0 0
HET M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET F #4 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 distributed Lymphoid hyperplasia
HET M #1 Prostate normal [MPATH:458] 0 0
HET M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #3 Thyroid normal [MPATH:458] 0 0
HET M #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #1 Thyroid normal [MPATH:458] 0 0
HET M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #4 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET F #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #4 Stomach [MA:0000353] inflammation [MPATH:212] 1 0 multi-localised Mild neutrophilic gastritis
HET F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #3 Stomach [MA:0000353] inflammation [MPATH:212] 3 0 multi-localised Marked neutrophilic gastritis with epithelial proteinosis
HET F #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Eye with optic nerve normal [MPATH:458] 0 0
HET M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET F #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET M #2 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 steatosis MPATH:622 multifocal to coalescing Hepatic lipidosis
HET M #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET F #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET M #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET M #2 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET F #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #4 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET F #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Liver [MA:0000358] lipid deposition [MPATH:42] 4 0 steatosis MPATH:622 distributed Hepatic lipidosis
HET F #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET F #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0

Associated histopathology images

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