Histopathology data for Rnf38

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HET M #1 Eye with optic nerve normal [MPATH:458] 0 0
HET F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #3 Eye with optic nerve developmental and structural abnormality [MPATH:55] 3 0 unilateral chronic Retinal dysplasia, anterior and posterior synechia, and retinal detachment.
HET M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #4 Mammary gland [MA:0000145] Not applicable
HET M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET F #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #1 Thyroid normal [MPATH:458] 0 0
HET M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Prostate normal [MPATH:458] 0 0
HET F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HET F #2 Epididymis [MA:0000397] Not applicable
HET F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET F #3 Seminal vesicle [MA:0000410] Not applicable
HET F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HET M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HET F #2 Prostate Not applicable
HET F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET F #2 Thyroid normal [MPATH:458] 0 0
HET M #1 Uterus [MA:0000389] Not applicable
HET M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #1 Ovary [MA:0000384] Not applicable
HET F #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HET M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #2 Testes Not applicable
HET M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #4 Thyroid normal [MPATH:458] 0 0
HET M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Seminal vesicle [MA:0000410] Not applicable
HET M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #1 Mammary gland [MA:0000145] Not applicable
HET F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #3
HET M #4 Eye with optic nerve normal [MPATH:458] 0 0
HET F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET F #3 Epididymis [MA:0000397] Not applicable
HET F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #4 Ovary [MA:0000384] Not applicable
HET M #1 Testes normal [MPATH:458] 0 0
HET F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #2 Eye with optic nerve normal [MPATH:458] 0 0
HET M #4 Uterus [MA:0000389] Not applicable
HET F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #3 Thyroid normal [MPATH:458] 0 0
HET M #4 Testes normal [MPATH:458] 0 0
HET F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HET M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET F #3 Testes Not applicable
HET M #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #4 Prostate normal [MPATH:458] 0 0
HET F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Prostate Not applicable
HET M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0

Associated histopathology images

Rnf38
heterozygote
Eye with optic nerve MA:0000261
MA:0000261 eye
Rnf38tm1b(KOMP)Wtsi
experimental

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter