Histopathology data for Radil

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #4 Tooth [MA:0000348] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Uterus [MA:0000389] Not applicable
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #4 Nasal cavity [MA:0000284] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM F #4 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM F #2 Nasal cavity [MA:0000284] normal [MPATH:458] 0 0
HOM M #3 Tongue [MA:0000347] normal [MPATH:458] 0 0
HOM F #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #4 Testes Not applicable
HOM F #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 subacute Gastritis, suppurative.
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Tooth [MA:0000348] normal [MPATH:458] 0 0
HOM F #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #4 Prostate Not applicable
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #4 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Nasal cavity [MA:0000284] normal [MPATH:458] 0 0
HOM M #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #3 Tooth [MA:0000348] normal [MPATH:458] 0 0
HOM M #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #4 Thyroid normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #4 Tongue [MA:0000347] normal [MPATH:458] 0 0
HOM M #1 Ear [MA:0000236] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Tooth [MA:0000348] normal [MPATH:458] 0 0
HOM F #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #4 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM F #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #4 Sternum [MA:0001331] normal [MPATH:458] process of degenerative change [MPATH:14] chronic
HOM M #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Sternum [MA:0001331] process of degenerative change [MPATH:14] 3 0 chronic Segmental sternum dislocation
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #4 Sternum [MA:0001331] 3 0 Segmental sternum dislocation
HOM F #4 Sternum [MA:0001331] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Tongue [MA:0000347] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] neoplasm [MPATH:218] 4 0 lymphoid neoplasms MPATH:513 chronic B-cell lymphoma
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM F #2 Prostate Not applicable
HOM F #2 Ear [MA:0000236] normal [MPATH:458] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM F #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM F #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #3 Nasal cavity [MA:0000284] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #1 Tongue [MA:0000347] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Ear [MA:0000236] normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Testes Not applicable
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] fibrosis [MPATH:181] 2 0 chronic Right ventricular epicardial fibrosis, focal
HOM F #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Ear [MA:0000236] normal [MPATH:458] 0 0
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM M #3 Testes normal [MPATH:458] 0 0
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0

Associated histopathology images

Radil
homozygote
Radilem1(IMPC)Tcp
experimental
Radil
homozygote
Lymph node MA:0000139
MA:0000139 lymph node
Radilem1(IMPC)Tcp
experimental
Radil
homozygote
Stomach MA:0000353
MA:0000353 stomach
Radilem1(IMPC)Tcp
experimental

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