Histopathology data for Prl7d1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #4 Adrenal gland [MA:0000116] 0 0
HOM F #4 Tibia [MA:0001361] 0 0
HOM F #4 Pituitary gland [MA:0000176] 0 0
HOM M #2 Ovary [MA:0000384] Not applicable
HOM F #3 Skin [MA:0000151] 0 0
HOM F #4 Sternum [MA:0001331] 0 0
HOM M #2 Heart [MA:0000072] 0 0
HOM M #1 White adipose tissue [MA:0000058] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM M #1 Skin [MA:0000151] 0 0
HOM F #4 Sciatic nerve [MA:0001172] 0 0
HOM M #2 Spleen [MA:0000141] 0 0
HOM M #2 Spinal cord [MA:0000216] 0 0
HOM M #2 Gall bladder [MA:0000356] 0 0
HOM F #3 White adipose tissue [MA:0000058] 0 0
HOM M #2 Brown adipose tissue [MA:0000057] 0 0
HOM F #4 Pancreas [MA:0000120] 0 0
HOM M #2 Epididymis [MA:0000397] 0 0
HOM F #4 Eye [MA:0000261] 0 0
HOM F #3 Testis [MA:0000411] Not applicable
HOM F #4 Esophagus [MA:0000352] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #4 Femur [MA:0001359] 0 0
HOM M #1 Tongue [MA:0000347] 0 0
HOM M #1 Small intestine [MA:0000337] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM M #1 Optic II nerve [MA:0001097] 0 0
HOM M #2 Mammary gland [MA:0000145] Not applicable
HOM M #1 Knee joint [MA:0000471] 0 0
HOM M #1 Nasal cavity [MA:0000284] 0 0
HOM F #4 Thymus [MA:0000142] 0 0
HOM M #2 Urinary bladder [MA:0000380] 0 0
HOM M #1 Femur [MA:0001359] 0 0
HOM F #3 Tooth [MA:0000348] 0 0
HOM M #1 Large intestine [MA:0000333] 0 0
HOM M #2 Seminal vesicle [MA:0000410] 0 0
HOM F #4 Lymph node [MA:0000139] 4 0 localized chronic B-cell lymphoma
HOM F #4 Urinary bladder [MA:0000380] 0 0
HOM M #1 Liver [MA:0000358] 0 0
HOM M #1 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Brain [MA:0000168] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM M #2 Sciatic nerve [MA:0001172] 0 0
HOM F #4 Heart [MA:0000072] 0 0
HOM F #4 Optic II nerve [MA:0001097] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HOM M #1 Stomach [MA:0000353] 0 0
HOM M #2 Skeletal muscle [MA:0003148] 0 0
HOM M #2 Adrenal gland [MA:0000116] 0 0
HOM M #2 Sternum [MA:0001331] 0 0
HOM M #2 Lymph node [MA:0000139] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM M #2 Pituitary gland [MA:0000176] 0 0
HOM F #3 Thyroid 0 0
HOM M #1 Ear [MA:0000236] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM M #1 Esophagus [MA:0000352] 0 0
HOM M #2 Pancreas [MA:0000120] 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM M #1 Tibia [MA:0001361] 0 0
HOM M #2 Tongue [MA:0000347] 0 0
HOM F #3 Ear [MA:0000236] 0 0
HOM F #4 Large intestine [MA:0000333] 0 0
HOM M #1 Salivary gland [MA:0000346] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM M #2 Nasal cavity [MA:0000284] 0 0
HOM F #4 Brown adipose tissue [MA:0000057] 0 0
HOM M #1 Kidney [MA:0000368] 0 0
HOM M #1 Thyroid 0 0
HOM F #4 Gall bladder [MA:0000356] 0 0
HOM M #2 Prostate gland [MA:0000404] 0 0
HOM F #3 Knee joint [MA:0000471] 0 0
HOM M #1 Testis [MA:0000411] 0 0
HOM M #1 Tooth [MA:0000348] 0 0
HOM F #4 Trachea [MA:0000441] 0 0
HOM M #1 Brain [MA:0000168] 0 0
HOM F #4 Lung [MA:0000415] 0 0
HOM M #2 Trachea [MA:0000441] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM M #2 Bone marrow [MA:0000134] 0 0
HOM F #4 Prostate gland [MA:0000404] Not applicable
HOM F #3 Small intestine [MA:0000337] 0 0
HOM M #2 Lung [MA:0000415] 0 0
HOM F #4 Bone marrow [MA:0000134] 0 0
HOM F #4 Ovary [MA:0000384] 0 0
HOM M #1 Spinal cord [MA:0000216] 0 0
HOM F #4 Testis [MA:0000411] Not applicable
HOM M #1 Urinary bladder [MA:0000380] 0 0
HOM M #1 Seminal vesicle [MA:0000410] 0 0
HOM M #1 Gall bladder [MA:0000356] 0 0
HOM F #4 Nasal cavity [MA:0000284] 0 0
HOM M #1 Spleen [MA:0000141] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM M #1 Trachea [MA:0000441] 0 0
HOM M #1 Brown adipose tissue [MA:0000057] 0 0
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM F #4 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #1 Prostate gland [MA:0000404] 0 0
HOM M #1 Epididymis [MA:0000397] 0 0
HOM M #1 Heart [MA:0000072] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM F #4 Tongue [MA:0000347] 0 0
HOM M #2 Knee joint [MA:0000471] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM M #2 Small intestine [MA:0000337] 0 0
HOM F #4 Brain [MA:0000168] 0 0
HOM F #3 Ovary [MA:0000384] 0 0
HOM M #2 Femur [MA:0001359] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM F #3 Tibia [MA:0001361] 0 0
HOM M #1 Pancreas [MA:0000120] 0 0
HOM M #2 Large intestine [MA:0000333] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM F #4 Mammary gland [MA:0000145] 0 0
HOM M #2 Eye [MA:0000261] 0 0
HOM F #3 Sternum [MA:0001331] 0 0
HOM F #4 Liver [MA:0000358] 0 0
HOM F #4 Salivary gland [MA:0000346] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #2 Thymus [MA:0000142] 0 0
HOM F #4 Uterus [MA:0000389] 0 0
HOM M #2 Liver [MA:0000358] 0 0
HOM F #4 White adipose tissue [MA:0000058] 0 0
HOM F #3 Brown adipose tissue [MA:0000057] 0 0
HOM M #2 White adipose tissue [MA:0000058] 0 0
HOM M #1 Pituitary gland [MA:0000176] 0 0
HOM F #4 Stomach [MA:0000353] 2 0 multi-localised subacute Gastritis, suppurative.
HOM M #2 Optic II nerve [MA:0001097] 0 0
HOM F #4 Knee joint [MA:0000471] 0 0
HOM M #1 Thymus [MA:0000142] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HOM M #2 Brain [MA:0000168] 0 0
HOM M #2 Stomach [MA:0000353] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM M #2 Salivary gland [MA:0000346] 0 0
HOM M #2 Tibia [MA:0001361] 0 0
HOM M #1 Lung [MA:0000415] 0 0
HOM M #2 Uterus [MA:0000389] Not applicable
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #4 Tooth [MA:0000348] 0 0
HOM M #1 Eye [MA:0000261] 0 0
HOM M #1 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM F #4 Spleen [MA:0000141] 0 0
HOM F #4 Small intestine [MA:0000337] 0 0
HOM M #2 Esophagus [MA:0000352] 0 0
HOM M #1 Lymph node [MA:0000139] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM F #3 Stomach [MA:0000353] 2 0 subacute multi-localised Gastritis, suppurative.
HOM F #3 Pituitary gland [MA:0000176] 0 0
HOM M #2 Tooth [MA:0000348] 0 0
HOM M #2 Skin [MA:0000151] 0 0
HOM M #2 Ear [MA:0000236] 0 0
HOM F #3 Nasal cavity [MA:0000284] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM M #2 Thyroid 0 0
HOM F #4 Spinal cord [MA:0000216] 0 0
HOM M #1 Bone marrow [MA:0000134] 0 0
HOM F #4 Skin [MA:0000151] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM M #2 Kidney [MA:0000368] 0 0
HOM F #4 Thyroid 0 0
HOM F #4 Kidney [MA:0000368] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Tongue [MA:0000347] 0 0
HOM F #4 Ear [MA:0000236] 0 0
HOM M #1 Adrenal gland [MA:0000116] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM M #1 Sternum [MA:0001331] 0 0
HOM M #2 Testis [MA:0000411] 0 0

Associated histopathology images

Prl7d1
homozygote
Prl7d1em1(IMPC)Tcp
experimental
Prl7d1
homozygote
Prl7d1em1(IMPC)Tcp
experimental
Prl7d1
homozygote
Prl7d1em1(IMPC)Tcp
experimental

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