Histopathology data for Polr3b

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HET M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HET F #4 Testes Not applicable
HET M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #1 Thyroid normal [MPATH:458] 0 0
HET F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET F #2 Tongue [MA:0000347] normal [MPATH:458] 0 0
HET F #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET M #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HET M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #4 Epididymis [MA:0000397] Not applicable
HET F #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #1 Testes normal [MPATH:458] 0 0
HET M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #3 Thyroid normal [MPATH:458] 0 0
HET F #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #3 Tongue [MA:0000347] normal [MPATH:458] 0 0
HET M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HET M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HET F #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #2 Thyroid normal [MPATH:458] 0 0
HET M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #3 Uterus [MA:0000389] Not applicable
HET F #4 Thyroid normal [MPATH:458] 0 0
HET M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HET F #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET F #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #1 Prostate normal [MPATH:458] 0 0
HET F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #1 Mammary gland [MA:0000145] Not applicable
HET F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #2 Seminal vesicle [MA:0000410] Not applicable
HET F #4 Eye with optic nerve normal [MPATH:458] 0 0
HET M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #3 Ovary [MA:0000384] Not applicable
HET F #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET F #2 Epididymis [MA:0000397] Not applicable
HET M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #1 Uterus [MA:0000389] Not applicable
HET F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Eye with optic nerve normal [MPATH:458] 0 0
HET M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #4 Prostate Not applicable
HET M #3 Mammary gland [MA:0000145] Not applicable
HET M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #1 Ovary [MA:0000384] Not applicable
HET F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HET M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #4 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET F #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET F #4 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET M #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #1 Tongue [MA:0000347] normal [MPATH:458] 0 0
HET F #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET F #4 Seminal vesicle [MA:0000410] Not applicable
HET F #2 Eye with optic nerve normal [MPATH:458] 0 0
HET F #2 Prostate Not applicable
HET M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET M #3 Testes normal [MPATH:458] 0 0
HET M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #4 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET F #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #3 Prostate normal [MPATH:458] 0 0
HET M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET F #4 Tongue [MA:0000347] normal [MPATH:458] 0 0
HET F #2 Sternum [MA:0001331] displacement and deformity [MPATH:67] 3 0 chronic localized Sternal segment dislocation
HET M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET M #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET F #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HET F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET F #2 Testes Not applicable
HET F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #3 Eye with optic nerve normal [MPATH:458] 0 0
HET M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0

Associated histopathology images

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