Histopathology data for Poc5

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #1 Trachea [MA:0000441] 0 0
HOM F #1 Eye [MA:0000261] 0 0
HOM F #1 Large intestine [MA:0000333] 0 0
HOM M #4 Eye [MA:0000261] 0 0
HOM M #2 Spinal cord [MA:0000216] 0 0
HOM M #2 Tongue [MA:0000347] 0 0
HOM F #1 Epididymis [MA:0000397] Not applicable
HOM M #2 Prostate gland [MA:0000404] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HOM F #1 Mammary gland [MA:0000145] 0 0
HOM F #1 Gall bladder [MA:0000356] 0 0
HOM F #1 Esophagus [MA:0000352] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HOM M #2 Esophagus [MA:0000352] 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM M #2 Bone marrow [MA:0000134] 0 0
HOM M #4 Knee joint [MA:0000471] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM F #1 Sciatic nerve [MA:0001172] 0 0
HOM M #2 Gall bladder [MA:0000356] 0 0
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM F #3 Thyroid 0 0
HOM M #2 Uterus [MA:0000389] Not applicable
HOM M #2 Thyroid 0 0
HOM M #2 Knee joint [MA:0000471] 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM M #2 Eye [MA:0000261] 0 0
HOM M #2 Thymus [MA:0000142] 0 0
HOM M #2 Sternum [MA:0001331] 0 0
HOM F #3 Testis [MA:0000411] Not applicable
HOM M #2 Trachea [MA:0000441] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM F #1 Uterus [MA:0000389] 0 0
HOM F #1 Thymus [MA:0000142] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #2 Pancreas [MA:0000120] 0 0
HOM F #1 Knee joint [MA:0000471] 0 0
HOM M #2 Large intestine [MA:0000333] 0 0
HOM F #1 Sternum [MA:0001331] 0 0
HOM F #1 Prostate gland [MA:0000404] Not applicable
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM M #2 Spleen [MA:0000141] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM F #3 Tongue [MA:0000347] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HOM M #2 Stomach [MA:0000353] 1 0 acute localized suppurative gastritis.
HOM M #2 Small intestine [MA:0000337] 0 0
HOM F #1 Tongue [MA:0000347] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #1 Spinal cord [MA:0000216] 0 0
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM F #1 Stomach [MA:0000353] 0 0
HOM F #1 Small intestine [MA:0000337] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM F #1 Urinary bladder [MA:0000380] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM F #3 Ovary [MA:0000384] 2 0 unilateral chronic Hemorrhagic follicular cyst, ovary.
HOM F #1 Kidney [MA:0000368] 0 0
HOM M #2 Ovary [MA:0000384] Not applicable
HOM M #2 Urinary bladder [MA:0000380] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM M #4 Tongue [MA:0000347] 0 0
HOM M #2 Liver [MA:0000358] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM M #2 Skeletal muscle [MA:0003148] 0 0
HOM F #1 Liver [MA:0000358] 0 0
HOM F #1 Spleen [MA:0000141] 0 0
HOM F #1 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM M #2 Kidney [MA:0000368] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HOM M #2 Brain [MA:0000168] 0 0
HOM M #2 Heart [MA:0000072] 0 0
HOM M #4 Salivary gland [MA:0000346] 0 0
HOM F #1 Salivary gland [MA:0000346] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM M #2 Seminal vesicle [MA:0000410] 0 0
HOM M #4 Spleen [MA:0000141] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM F #1 Adrenal gland [MA:0000116] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM F #3 Tibia [MA:0001361] 0 0
HOM F #1 Ovary [MA:0000384] 0 0
HOM M #4 Lung [MA:0000415] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #1 Seminal vesicle [MA:0000410] Not applicable
HOM M #4 Ovary [MA:0000384] Not applicable
HOM F #1 Optic II nerve [MA:0001097] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HOM M #2 Adrenal gland [MA:0000116] 0 0
HOM M #4 Lymph node [MA:0000139] 0 0
HOM M #2 Optic II nerve [MA:0001097] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM M #2 Lymph node [MA:0000139] 0 0
HOM F #1 Testis [MA:0000411] Not applicable
HOM F #3 Knee joint [MA:0000471] 0 0
HOM F #3 Sternum [MA:0001331] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM F #1 Brain [MA:0000168] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM F #1 Pancreas [MA:0000120] 0 0
HOM F #1 Lymph node [MA:0000139] 0 0
HOM M #2 Testis [MA:0000411] 0 0
HOM F #1 Skin [MA:0000151] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #2 Skin [MA:0000151] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM M #2 Salivary gland [MA:0000346] 0 0
HOM M #4 Femur [MA:0001359] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0
HOM F #1 Femur [MA:0001359] 0 0
HOM F #3 Brain [MA:0000168] 0 0
HOM M #2 Mammary gland [MA:0000145] Not applicable
HOM F #3 Heart [MA:0000072] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HOM F #1 Bone marrow [MA:0000134] 0 0
HOM M #2 Lung [MA:0000415] 0 0
HOM M #2 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Sternum [MA:0001331] 0 0
HOM M #2 Tibia [MA:0001361] 0 0
HOM F #1 Heart [MA:0000072] 0 0
HOM F #1 Thyroid 0 0
HOM F #1 Lung [MA:0000415] 0 0
HOM M #2 Epididymis [MA:0000397] 0 0
HOM M #4 Tibia [MA:0001361] 0 0
HOM M #4 Thyroid 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #1 Tibia [MA:0001361] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #3 Femur [MA:0001359] 0 0
HOM M #2 Femur [MA:0001359] 0 0
HOM M #4 Esophagus [MA:0000352] 0 0

Associated histopathology images

Poc5
homozygote
Stomach - MA term MA:0000353
Poc5em1(IMPC)Tcp
experimental
Poc5
homozygote
Ovary - MA term MA:0000384
Poc5em1(IMPC)Tcp
experimental

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