Histopathology data for Plxna2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #4 Eye with optic nerve developmental and structural abnormality [MPATH:55] Not applicable 0 Persistent hyaloid artery
HOM F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #4 Prostate normal [MPATH:458] 0 0
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #4 Skin [MA:0000151] process of degenerative change [MPATH:14] 3 0 cyst MPATH:62 localized Hair follicular cyst
HOM M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Testes normal [MPATH:458] 0 0
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve developmental and structural abnormality [MPATH:55] Not applicable 0 Persistent hyaloid artery
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Thyroid normal [MPATH:458] 0 0
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Thyroid normal [MPATH:458] 0 0
HOM F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #1 Sternum [MA:0001331] process of degenerative change [MPATH:14] 2 0 transmural Transmural fissure (early joint dislocation/subluxation)
HOM F #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0

Associated histopathology images

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