Histopathology data for Paqr6

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #3 Testes normal [MPATH:458] 0 0
HOM F #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #4 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM M #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #4 Prostate Not applicable
HOM F #4 Testes Not applicable
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM F #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM F #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #4 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Prostate Not applicable
HOM F #4 Thyroid normal [MPATH:458] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM M #1 Uterus [MA:0000389] Not applicable
HOM F #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM F #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM F #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Uterus [MA:0000389] Not applicable
HOM F #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Testes Not applicable
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #4 Lung [MA:0000415] normal [MPATH:458] 0 0

Associated histopathology images

Paqr6
homozygote
Paqr6tm1b(KOMP)Wtsi
experimental
Paqr6
homozygote
Paqr6tm1b(KOMP)Wtsi
experimental

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