Histopathology data for Iqgap1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Trachea [MA:0000441] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Urinary bladder [MA:0000380] 0 0
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM M #1 Adrenal gland [MA:0000116] 0 0
HOM M #4 Esophagus [MA:0000352] 0 0
HOM M #1 Tongue [MA:0000347] 0 0
HOM M #4 Femur [MA:0001359] 0 0
HOM F #2 Gall bladder [MA:0000356] 0 0
HOM M #4 Sternum [MA:0001331] 0 0
HOM M #1 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Ovary [MA:0000384] 0 0
HOM M #1 Knee joint [MA:0000471] 0 0
HOM M #1 Spinal cord [MA:0000216] 0 0
HOM F #2 Spleen [MA:0000141] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HOM M #1 Brain [MA:0000168] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM M #1 Ovary [MA:0000384] Not applicable
HOM M #1 Sternum [MA:0001331] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HOM M #1 Sternum [MA:0001331] 3 0 Sternal segment dislocation.
HOM M #4 Tibia [MA:0001361] 0 0
HOM M #1 Seminal vesicle [MA:0000410] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM M #1 Gall bladder [MA:0000356] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM M #4 Lymph node [MA:0000139] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Eye [MA:0000261] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM F #2 Heart [MA:0000072] 0 0
HOM F #2 Lymph node [MA:0000139] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM F #2 Tibia [MA:0001361] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM M #1 Optic II nerve [MA:0001097] 0 0
HOM F #2 Stomach [MA:0000353] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM F #2 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM M #1 Urinary bladder [MA:0000380] 0 0
HOM M #1 Sternum [MA:0001331] localized chronic
HOM F #3 Testis [MA:0000411] Not applicable
HOM M #4 Skin [MA:0000151] 0 0
HOM F #2 Lung [MA:0000415] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM M #1 Spleen [MA:0000141] 0 0
HOM F #2 Skeletal muscle [MA:0003148] 0 0
HOM F #2 Large intestine [MA:0000333] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM F #3 Tibia [MA:0001361] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #2 Mammary gland [MA:0000145] 0 0
HOM M #1 Kidney [MA:0000368] 0 0
HOM F #2 Sternum [MA:0001331] 0 0
HOM F #2 Adrenal gland [MA:0000116] 0 0
HOM M #4 Spleen [MA:0000141] 0 0
HOM F #2 Tongue [MA:0000347] 0 0
HOM F #2 Bone marrow [MA:0000134] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM F #2 Pancreas [MA:0000120] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #4 Knee joint [MA:0000471] 0 0
HOM M #1 Bone marrow [MA:0000134] 0 0
HOM M #1 Thyroid 0 0
HOM F #2 Ovary [MA:0000384] 0 0
HOM M #1 Stomach [MA:0000353] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM M #4 Thyroid 0 0
HOM F #2 Prostate gland [MA:0000404] Not applicable
HOM F #3 Brain [MA:0000168] 0 0
HOM M #1 Testis [MA:0000411] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM M #4 Salivary gland [MA:0000346] 0 0
HOM F #3 Knee joint [MA:0000471] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HOM F #2 Optic II nerve [MA:0001097] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HOM F #2 Small intestine [MA:0000337] 0 0
HOM F #2 Liver [MA:0000358] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM M #1 Trachea [MA:0000441] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM F #3 Thyroid 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM M #1 Prostate gland [MA:0000404] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM M #1 Small intestine [MA:0000337] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM F #2 Eye [MA:0000261] 0 0
HOM M #1 Salivary gland [MA:0000346] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM F #2 Esophagus [MA:0000352] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HOM M #1 Lung [MA:0000415] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HOM M #1 Skin [MA:0000151] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM F #2 Uterus [MA:0000389] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #2 Salivary gland [MA:0000346] 0 0
HOM M #1 Eye [MA:0000261] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM M #1 Pancreas [MA:0000120] 0 0
HOM F #2 Brain [MA:0000168] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HOM M #1 Heart [MA:0000072] 0 0
HOM F #3 Tongue [MA:0000347] 0 0
HOM M #1 Large intestine [MA:0000333] 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM F #2 Thymus [MA:0000142] 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM M #1 Esophagus [MA:0000352] 0 0
HOM F #2 Femur [MA:0001359] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM M #4 Pancreas [MA:0000120] 0 0
HOM M #1 Thymus [MA:0000142] 0 0
HOM F #2 Thyroid 0 0
HOM M #1 Epididymis [MA:0000397] 0 0
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #1 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Tongue [MA:0000347] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM M #1 Femur [MA:0001359] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #1 Tibia [MA:0001361] 0 0
HOM F #2 Knee joint [MA:0000471] 0 0
HOM F #2 Testis [MA:0000411] Not applicable
HOM F #3 Sternum [MA:0001331] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM M #4 Lung [MA:0000415] 0 0
HOM F #2 Skin [MA:0000151] 0 0
HOM M #1 Liver [MA:0000358] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM F #2 Kidney [MA:0000368] 0 0
HOM M #1 Lymph node [MA:0000139] 0 0
HOM F #2 Spinal cord [MA:0000216] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0

Associated histopathology images

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