Histopathology data for Idh1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Lymph node [MA:0000139] 0 0
HOM F #3 Sternum [MA:0001331] 0 0
HOM M #1 Thyroid 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM M #1 Heart [MA:0000072] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM F #2 Kidney [MA:0000368] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM M #1 Eye [MA:0000261] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM M #1 Optic II nerve [MA:0001097] 0 0
HOM F #2 Esophagus [MA:0000352] 0 0
HOM F #2 Spleen [MA:0000141] 0 0
HOM M #1 Femur [MA:0001359] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM F #2 Sternum [MA:0001331] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM M #1 Skeletal muscle [MA:0003148] 0 0
HOM M #1 Tooth [MA:0000348] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HOM M #1 Spinal cord [MA:0000216] 0 0
HOM F #3 Tooth [MA:0000348] 0 0
HOM M #4 Tongue [MA:0000347] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM F #2 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Thyroid 0 0
HOM F #2 Ear [MA:0000236] 0 0
HOM F #2 Thymus [MA:0000142] 0 0
HOM M #1 Prostate gland [MA:0000404] 0 0
HOM M #4 Ear [MA:0000236] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM M #4 Lung [MA:0000415] 0 0
HOM F #2 Large intestine [MA:0000333] 0 0
HOM M #1 Urinary bladder [MA:0000380] 0 0
HOM F #2 Pancreas [MA:0000120] 0 0
HOM F #2 Tongue [MA:0000347] 0 0
HOM M #1 Lung [MA:0000415] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HOM M #1 Small intestine [MA:0000337] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM M #4 Salivary gland [MA:0000346] 0 0
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM F #2 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM F #2 Stomach [MA:0000353] 0 0
HOM M #1 Testis [MA:0000411] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HOM M #1 Adrenal gland [MA:0000116] 0 0
HOM M #4 Tooth [MA:0000348] 0 0
HOM M #1 Gall bladder [MA:0000356] 0 0
HOM M #4 Esophagus [MA:0000352] 0 0
HOM F #3 Thyroid 0 0
HOM F #2 Adrenal gland [MA:0000116] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #4 Nasal cavity [MA:0000284] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM F #3 Ear [MA:0000236] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HOM M #1 Bone marrow [MA:0000134] 0 0
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM M #1 Brain [MA:0000168] 1 0 distributed Dilation of fourth ventricle
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM M #1 Stomach [MA:0000353] 0 0
HOM M #1 Tongue [MA:0000347] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM F #2 Urinary bladder [MA:0000380] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM F #2 Prostate gland [MA:0000404] Not applicable
HOM F #2 Salivary gland [MA:0000346] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM M #1 Salivary gland [MA:0000346] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM M #4 Spleen [MA:0000141] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM F #2 Tooth [MA:0000348] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM M #1 Thymus [MA:0000142] 0 0
HOM F #2 Eye [MA:0000261] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM F #2 Optic II nerve [MA:0001097] 0 0
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM F #2 Mammary gland [MA:0000145] 0 0
HOM M #1 Kidney [MA:0000368] 0 0
HOM F #2 Thyroid 0 0
HOM F #3 Testis [MA:0000411] Not applicable
HOM M #1 Esophagus [MA:0000352] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM M #1 Spleen [MA:0000141] 0 0
HOM M #1 Sternum [MA:0001331] 3 0 segmental chronic-active Sternal segment dislocation
HOM F #2 Uterus [MA:0000389] 0 0
HOM M #1 Seminal vesicle [MA:0000410] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #4 Sternum [MA:0001331] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM F #2 Bone marrow [MA:0000134] 0 0
HOM M #1 Skin [MA:0000151] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM F #3 Brain [MA:0000168] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM F #2 Brain [MA:0000168] 1 0 distributed Dilation of fourth ventricle
HOM M #4 Lymph node [MA:0000139] 0 0
HOM M #1 Ear [MA:0000236] 0 0
HOM M #1 Trachea [MA:0000441] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HOM F #2 Testis [MA:0000411] Not applicable
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM M #1 Nasal cavity [MA:0000284] 0 0
HOM F #2 Liver [MA:0000358] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM F #2 Spinal cord [MA:0000216] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM F #3 Ovary [MA:0000384] 0 0
HOM F #2 Femur [MA:0001359] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM M #1 Liver [MA:0000358] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM F #2 Nasal cavity [MA:0000284] 0 0
HOM F #2 Gall bladder [MA:0000356] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Ovary [MA:0000384] 0 0
HOM F #2 Skin [MA:0000151] 0 0
HOM M #1 Lymph node [MA:0000139] 0 0
HOM M #1 Sciatic nerve [MA:0001172] 0 0
HOM M #1 Epididymis [MA:0000397] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM M #4 Femur [MA:0001359] 0 0
HOM F #2 Trachea [MA:0000441] 0 0
HOM M #1 Large intestine [MA:0000333] 0 0
HOM F #3 Tongue [MA:0000347] 0 0
HOM F #2 Heart [MA:0000072] 0 0
HOM F #3 Nasal cavity [MA:0000284] 0 0
HOM M #4 Eye [MA:0000261] 0 0
HOM M #1 Pancreas [MA:0000120] 0 0
HOM F #2 Lung [MA:0000415] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM F #2 Small intestine [MA:0000337] 0 0

Associated histopathology images

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