Histopathology data for Greb1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #1 Spinal cord [MA:0000216] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #3 Thyroid 0 0
HOM M #1 Spleen [MA:0000141] 0 0
HOM M #4 Esophagus [MA:0000352] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM M #1 Large intestine [MA:0000333] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HOM F #2 Pancreas [MA:0000120] 0 0
HOM F #2 Heart [MA:0000072] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM F #2 Skin [MA:0000151] 0 0
HOM M #1 Epididymis [MA:0000397] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM F #2 Mammary gland [MA:0000145] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM M #4 Trachea [MA:0000441] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM M #1 Femur [MA:0001359] 0 0
HOM M #1 Salivary gland [MA:0000346] 0 0
HOM F #2 Eye [MA:0000261] localized chronic Persistent hyaloid artery.
HOM F #3 Brain [MA:0000168] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM M #1 Stomach [MA:0000353] 0 0
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Sciatic nerve [MA:0001172] 0 0
HOM F #2 Testis [MA:0000411] Not applicable
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM M #1 Kidney [MA:0000368] 0 0
HOM M #1 Brain [MA:0000168] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HOM M #1 Trachea [MA:0000441] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM F #2 Bone marrow [MA:0000134] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HOM M #1 Small intestine [MA:0000337] 0 0
HOM M #1 Gall bladder [MA:0000356] 0 0
HOM F #2 Optic II nerve [MA:0001097] 0 0
HOM M #1 Seminal vesicle [MA:0000410] 0 0
HOM F #2 Spleen [MA:0000141] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HOM M #1 Heart [MA:0000072] 0 0
HOM M #1 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM F #2 Lung [MA:0000415] 0 0
HOM F #2 Small intestine [MA:0000337] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM M #4 Thyroid 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #2 Thymus [MA:0000142] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #1 Optic II nerve [MA:0001097] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HOM M #1 Thyroid 0 0
HOM F #2 Gall bladder [MA:0000356] 0 0
HOM F #2 Ovary [MA:0000384] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM M #4 Spleen [MA:0000141] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #1 Liver [MA:0000358] 0 0
HOM M #1 Adrenal gland [MA:0000116] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0
HOM M #1 Testis [MA:0000411] 0 0
HOM M #1 Bone marrow [MA:0000134] 0 0
HOM F #2 Trachea [MA:0000441] 0 0
HOM F #2 Brain [MA:0000168] 0 0
HOM F #2 Kidney [MA:0000368] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM F #2 Esophagus [MA:0000352] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Liver [MA:0000358] 0 0
HOM M #4 Eye [MA:0000261] chronic multi-localised Detachment of inner limiting membrane, retina.
HOM F #2 Thyroid 0 0
HOM F #2 Uterus [MA:0000389] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM M #1 Thymus [MA:0000142] 0 0
HOM M #1 Pancreas [MA:0000120] 0 0
HOM M #4 Lung [MA:0000415] 0 0
HOM F #2 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM M #1 Urinary bladder [MA:0000380] 0 0
HOM M #1 Lung [MA:0000415] 0 0
HOM M #1 Sciatic nerve [MA:0001172] 0 0
HOM M #1 Prostate gland [MA:0000404] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM F #2 Lymph node [MA:0000139] 0 0
HOM M #1 Eye [MA:0000261] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM F #2 Urinary bladder [MA:0000380] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM M #4 Femur [MA:0001359] 0 0
HOM M #4 Salivary gland [MA:0000346] 0 0
HOM F #2 Femur [MA:0001359] 0 0
HOM M #4 Lymph node [MA:0000139] 0 0
HOM F #2 Adrenal gland [MA:0000116] 0 0
HOM F #3 Ovary [MA:0000384] 0 0
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HOM F #2 Salivary gland [MA:0000346] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM M #1 Esophagus [MA:0000352] 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM F #2 Large intestine [MA:0000333] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HOM F #3 Eye [MA:0000261] multi-localised chronic Detachment of inner limiting membrane, retina.
HOM F #2 Stomach [MA:0000353] 0 0
HOM F #2 Prostate gland [MA:0000404] Not applicable
HOM F #3 Testis [MA:0000411] Not applicable
HOM F #2 Spinal cord [MA:0000216] 0 0
HOM M #1 Lymph node [MA:0000139] 0 0
HOM M #1 Skin [MA:0000151] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable

Associated histopathology images

Greb1
homozygote
Greb1tm1b(KOMP)Wtsi
experimental
Greb1
homozygote
Greb1tm1b(KOMP)Wtsi
experimental
Greb1
homozygote
Greb1tm1b(KOMP)Wtsi
experimental

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