Histopathology data for Gpc5

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Prostate normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #4 Eye with optic nerve developmental dysplasia [MPATH:64] 1 0 multi-localised Retinal dysplasia
HOM M #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #4 Thyroid normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 distributed Lymphoid hyperplasia
HOM F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #4 Testes normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM M #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #3 Thyroid normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] hemorrhage and non-specified extravasation [MPATH:119] 2 0 Sinus erythrocytosis
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0

Associated histopathology images

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