Histopathology data for Gpc2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HET F #7 Uterus [MA:0000389] 0 0
HOM F #1 Spinal cord [MA:0000216] 0 0
HOM M #3 Adrenal gland [MA:0000116] 0 0
HOM F #8 Optic II nerve [MA:0001097] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM F #1 Sternum [MA:0001331] 0 0
HOM F #8 Liver [MA:0000358] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM F #8 Thymus [MA:0000142] 0 0
HOM F #1 Prostate gland [MA:0000404] Not applicable
HOM F #1 Heart [MA:0000072] 0 0
HET M #6 Eye [MA:0000261] 0 0
HOM F #1 Kidney [MA:0000368] 0 0
HET M #6 Bone marrow [MA:0000134] 0 0
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM M #3 Pancreas [MA:0000120] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM F #8 Mammary gland [MA:0000145] 0 0
HET M #5 Tongue [MA:0000347] 0 0
HOM M #3 Brain [MA:0000168] 0 0
HOM M #4 Femur [MA:0001359] 0 0
HET M #5 Gall bladder [MA:0000356] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM M #3 Spinal cord [MA:0000216] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HET M #6 Ear [MA:0000236] 0 0
HOM M #3 Prostate gland [MA:0000404] 0 0
HOM F #1 Pancreas [MA:0000120] 0 0
HET M #6 Spleen [MA:0000141] 0 0
HET F #7 Spleen [MA:0000141] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #1 Adrenal gland [MA:0000116] 0 0
HOM F #8 Skeletal muscle [MA:0003148] 0 0
HOM F #8 Sciatic nerve [MA:0001172] 0 0
HET F #2 Kidney [MA:0000368] 0 0
HOM F #8 Seminal vesicle [MA:0000410] Not applicable
HOM M #3 Heart [MA:0000072] chronic focally extensive
HET F #2 Pancreas [MA:0000120] 0 0
HET M #5 Optic II nerve [MA:0001097] 0 0
HOM M #4 Lymph node [MA:0000139] Not applicable 0 Early lymphoma
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HET F #2 Skin [MA:0000151] 0 0
HET M #5 Large intestine [MA:0000333] 0 0
HOM F #8 Testis [MA:0000411] Not applicable
HET M #6 Thyroid 0 0
HOM M #3 Trachea [MA:0000441] 0 0
HET M #5 Seminal vesicle [MA:0000410] 0 0
HET F #2 Nasal cavity [MA:0000284] 0 0
HET M #6 Epididymis [MA:0000397] 0 0
HET M #5 Lung [MA:0000415] 0 0
HET F #2 Adrenal gland [MA:0000116] 0 0
HOM M #4 Ear [MA:0000236] 0 0
HOM F #1 Brain [MA:0000168] 0 0
HET M #6 Skin [MA:0000151] 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #1 Skin [MA:0000151] 0 0
HET M #5 Liver [MA:0000358] 0 0
HOM F #1 Nasal cavity [MA:0000284] 0 0
HOM M #4 Eye [MA:0000261] 0 0
HOM M #4 Tooth [MA:0000348] 0 0
HET F #2 Small intestine [MA:0000337] 0 0
HET M #6 Uterus [MA:0000389] Not applicable
HET F #2 Ovary [MA:0000384] 0 0
HET M #5 Sciatic nerve [MA:0001172] 0 0
HET M #5 Testis [MA:0000411] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HET M #5 Femur [MA:0001359] 0 0
HET F #2 Spleen [MA:0000141] 0 0
HOM F #1 Uterus [MA:0000389] 0 0
HOM F #8 Epididymis [MA:0000397] Not applicable
HOM M #3 Skin [MA:0000151] 0 0
HOM F #8 Femur [MA:0001359] 0 0
HET F #2 Heart [MA:0000072] 0 0
HET F #2 Uterus [MA:0000389] 0 0
HOM F #1 Ovary [MA:0000384] 0 0
HET M #5 Trachea [MA:0000441] 0 0
HET F #7 Skin [MA:0000151] 0 0
HOM F #8 Tongue [MA:0000347] 0 0
HOM M #3 Nasal cavity [MA:0000284] 0 0
HOM F #1 Spleen [MA:0000141] 0 0
HOM M #3 Large intestine [MA:0000333] 0 0
HOM F #8 Bone marrow [MA:0000134] 0 0
HET F #7 Epididymis [MA:0000397] Not applicable
HET F #2 Trachea [MA:0000441] 0 0
HET M #6 Femur [MA:0001359] 0 0
HET F #7 Ovary [MA:0000384] 0 0
HOM F #8 Esophagus [MA:0000352] 0 0
HET M #5 Tooth [MA:0000348] 0 0
HOM M #4 Salivary gland [MA:0000346] 0 0
HET M #6 Sternum [MA:0001331] 0 0
HET F #2 Thyroid 0 0
HET F #2 Salivary gland [MA:0000346] 0 0
HET M #6 Optic II nerve [MA:0001097] 0 0
HET M #6 Prostate gland [MA:0000404] 0 0
HOM M #3 Urinary bladder [MA:0000380] 0 0
HET F #7 Tooth [MA:0000348] 0 0
HET F #7 Adrenal gland [MA:0000116] 0 0
HET M #6 Mammary gland [MA:0000145] Not applicable
HOM M #4 Spleen [MA:0000141] 0 0
HOM M #3 Heart [MA:0000072] 1 0 Right ventricular epicardial fibrosis, focal
HOM M #3 Spleen [MA:0000141] 0 0
HOM F #8 Uterus [MA:0000389] 0 0
HOM M #3 Heart [MA:0000072] 0 0
HET F #2 Urinary bladder [MA:0000380] 0 0
HET M #5 Epididymis [MA:0000397] 0 0
HET F #7 Liver [MA:0000358] 0 0
HET F #7 Heart [MA:0000072] 0 0
HOM F #1 Trachea [MA:0000441] 0 0
HET F #2 Brain [MA:0000168] 0 0
HOM F #1 Thyroid 0 0
HET M #5 Ovary [MA:0000384] Not applicable
HOM M #4 Lung [MA:0000415] 0 0
HOM F #1 Urinary bladder [MA:0000380] 0 0
HOM F #8 Lung [MA:0000415] 0 0
HET M #6 Testis [MA:0000411] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HET M #6 Seminal vesicle [MA:0000410] 0 0
HET F #2 Eye [MA:0000261] 0 0
HOM M #4 Tongue [MA:0000347] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable
HOM F #8 Tooth [MA:0000348] 0 0
HOM F #1 Ear [MA:0000236] 0 0
HOM M #3 Eye [MA:0000261] 0 0
HET M #5 Esophagus [MA:0000352] 0 0
HET F #7 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HET F #2 Large intestine [MA:0000333] 0 0
HOM F #8 Small intestine [MA:0000337] 0 0
HOM M #4 Thyroid 0 0
HET M #5 Heart [MA:0000072] focally extensive chronic
HOM M #3 Sternum [MA:0001331] Not applicable 0 chronic focally extensive Sternal dislocation with reparative chondroid hyperplasia ('calus')
HET M #6 Large intestine [MA:0000333] 0 0
HOM F #8 Lymph node [MA:0000139] 0 0
HET F #7 Gall bladder [MA:0000356] 0 0
HET M #5 Stomach [MA:0000353] 0 0
HET M #5 Adrenal gland [MA:0000116] 0 0
HOM F #1 Eye [MA:0000261] 0 0
HOM M #4 Nasal cavity [MA:0000284] 0 0
HET F #2 Ear [MA:0000236] 0 0
HET F #7 Small intestine [MA:0000337] 0 0
HET F #2 Spinal cord [MA:0000216] 0 0
HET M #6 Spinal cord [MA:0000216] 0 0
HET F #2 Seminal vesicle [MA:0000410] Not applicable
HET F #2 Prostate gland [MA:0000404] Not applicable
HET F #2 Testis [MA:0000411] Not applicable
HET F #2 Sternum [MA:0001331] 0 0
HET M #5 Skeletal muscle [MA:0003148] 0 0
HOM F #1 Large intestine [MA:0000333] 0 0
HOM M #3 Salivary gland [MA:0000346] 0 0
HET M #5 Pancreas [MA:0000120] 0 0
HOM F #1 Salivary gland [MA:0000346] 0 0
HET M #5 Kidney [MA:0000368] 0 0
HET M #6 Thymus [MA:0000142] 0 0
HET M #5 Bone marrow [MA:0000134] 0 0
HET F #7 Kidney [MA:0000368] 0 0
HET F #7 Bone marrow [MA:0000134] 0 0
HET M #6 Salivary gland [MA:0000346] 0 0
HET F #2 Optic II nerve [MA:0001097] 0 0
HET F #7 Lymph node [MA:0000139] 0 0
HOM M #3 Thymus [MA:0000142] 0 0
HET F #7 Pancreas [MA:0000120] 0 0
HOM F #8 Stomach [MA:0000353] 0 0
HET M #5 Lymph node [MA:0000139] 0 0
HOM F #8 Gall bladder [MA:0000356] 0 0
HOM M #3 Epididymis [MA:0000397] 0 0
HOM F #8 Sternum [MA:0001331] 0 0
HET F #2 Femur [MA:0001359] 0 0
HET F #7 Large intestine [MA:0000333] 0 0
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0
HOM M #4 Sternum [MA:0001331] 0 0
HET F #2 Mammary gland [MA:0000145] 0 0
HOM F #8 Heart [MA:0000072] 0 0
HOM F #1 Seminal vesicle [MA:0000410] Not applicable
HET M #5 Small intestine [MA:0000337] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HET F #2 Sciatic nerve [MA:0001172] 0 0
HOM F #1 Testis [MA:0000411] Not applicable
HOM F #1 Liver [MA:0000358] 0 0
HET F #2 Gall bladder [MA:0000356] 0 0
HET F #7 Lung [MA:0000415] 0 0
HOM F #8 Spinal cord [MA:0000216] 0 0
HOM F #1 Thymus [MA:0000142] 0 0
HET M #6 Trachea [MA:0000441] 0 0
HET M #5 Heart [MA:0000072] 0 0
HOM F #1 Optic II nerve [MA:0001097] 0 0
HOM F #1 Femur [MA:0001359] 0 0
HOM F #8 Prostate gland [MA:0000404] Not applicable
HET F #2 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HET M #5 Heart [MA:0000072] 1 0 Right ventricular epicardial fibrosis, focal
HET F #7 Stomach [MA:0000353] 0 0
HOM F #8 Kidney [MA:0000368] 0 0
HOM F #8 Pancreas [MA:0000120] 0 0
HOM F #1 Mammary gland [MA:0000145] 0 0
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #1 Sciatic nerve [MA:0001172] 0 0
HOM M #3 Seminal vesicle [MA:0000410] 0 0
HET M #6 Urinary bladder [MA:0000380] 0 0
HOM M #3 Ear [MA:0000236] 0 0
HOM M #3 Optic II nerve [MA:0001097] 0 0
HET F #7 Esophagus [MA:0000352] 0 0
HET F #2 Lymph node [MA:0000139] Not applicable 0 Early lymphoma
HET F #2 Tongue [MA:0000347] 0 0
HET M #6 Esophagus [MA:0000352] 0 0
HET F #2 Thymus [MA:0000142] 0 0
HOM M #3 Testis [MA:0000411] 0 0
HOM F #1 Lymph node [MA:0000139] 0 0
HOM M #3 Liver [MA:0000358] 0 0
HOM M #3 Thyroid 0 0
HET M #6 Lung [MA:0000415] 0 0
HET M #5 Uterus [MA:0000389] Not applicable
HOM F #1 Skeletal muscle [MA:0003148] 0 0
HOM M #3 Sciatic nerve [MA:0001172] 0 0
HOM F #8 Adrenal gland [MA:0000116] 0 0
HET M #5 Spinal cord [MA:0000216] 0 0
HET M #5 Prostate gland [MA:0000404] 0 0
HET M #5 Sternum [MA:0001331] Not applicable 0 chronic focally extensive Sternal dislocation with reparative chondroid hyperplasia ('calus')
HOM F #8 Brain [MA:0000168] 0 0
HET F #7 Trachea [MA:0000441] 0 0
HET M #6 Nasal cavity [MA:0000284] 0 0
HET F #2 Epididymis [MA:0000397] Not applicable
HOM M #3 Femur [MA:0001359] 0 0
HET F #7 Femur [MA:0001359] 0 0
HET M #6 Ovary [MA:0000384] Not applicable
HOM F #1 Tongue [MA:0000347] 0 0
HET M #6 Brain [MA:0000168] 0 0
HOM F #8 Skin [MA:0000151] 0 0
HET F #7 Tongue [MA:0000347] 0 0
HET F #7 Sciatic nerve [MA:0001172] 0 0
HOM F #8 Ovary [MA:0000384] 0 0
HOM F #1 Epididymis [MA:0000397] Not applicable
HET F #2 Esophagus [MA:0000352] 0 0
HOM M #3 Tongue [MA:0000347] 0 0
HET F #7 Brain [MA:0000168] 0 0
HET M #5 Nasal cavity [MA:0000284] 0 0
HOM F #8 Nasal cavity [MA:0000284] 0 0
HET M #5 Skin [MA:0000151] 0 0
HET M #6 Tongue [MA:0000347] 0 0
HET M #5 Brain [MA:0000168] 0 0
HET M #6 Skeletal muscle [MA:0003148] 0 0
HOM F #1 Esophagus [MA:0000352] 0 0
HOM M #4 Esophagus [MA:0000352] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HET M #5 Ear [MA:0000236] 0 0
HOM F #8 Spleen [MA:0000141] 0 0
HOM M #3 Uterus [MA:0000389] Not applicable
HET M #6 Heart [MA:0000072] 0 0
HOM F #1 Stomach [MA:0000353] 0 0
HET M #6 Liver [MA:0000358] 0 0
HET M #5 Eye [MA:0000261] 0 0
HOM M #3 Lung [MA:0000415] 0 0
HET F #7 Nasal cavity [MA:0000284] 0 0
HOM F #8 Urinary bladder [MA:0000380] 0 0
HET F #7 Seminal vesicle [MA:0000410] Not applicable
HET F #2 Bone marrow [MA:0000134] 0 0
HET M #6 Lymph node [MA:0000139] 0 0
HET M #5 Thyroid 0 0
HET F #7 Testis [MA:0000411] Not applicable
HET M #6 Kidney [MA:0000368] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HET F #7 Optic II nerve [MA:0001097] 0 0
HOM M #3 Small intestine [MA:0000337] 0 0
HOM F #8 Trachea [MA:0000441] 0 0
HOM M #3 Esophagus [MA:0000352] 0 0
HET F #2 Stomach [MA:0000353] 0 0
HET M #6 Small intestine [MA:0000337] 0 0
HET F #2 Tooth [MA:0000348] 0 0
HOM F #1 Bone marrow [MA:0000134] 0 0
HOM F #1 Lung [MA:0000415] 0 0
HET F #7 Spinal cord [MA:0000216] 0 0
HET F #7 Ear [MA:0000236] 0 0
HOM F #8 Thyroid 0 0
HET M #6 Adrenal gland [MA:0000116] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HET F #7 Sternum [MA:0001331] 0 0
HET M #6 Sciatic nerve [MA:0001172] 0 0
HET F #7 Prostate gland [MA:0000404] Not applicable
HOM M #4 Small intestine [MA:0000337] 0 0
HOM F #1 Small intestine [MA:0000337] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HET M #5 Urinary bladder [MA:0000380] 0 0
HET M #5 Spleen [MA:0000141] 0 0
HOM M #3 Skeletal muscle [MA:0003148] 0 0
HET F #7 Eye [MA:0000261] 0 0
HOM F #1 Tooth [MA:0000348] 0 0
HET M #6 Pancreas [MA:0000120] 0 0
HOM M #3 Lymph node [MA:0000139] 0 0
HOM M #3 Kidney [MA:0000368] 0 0
HOM F #8 Ear [MA:0000236] 0 0
HET M #5 Thymus [MA:0000142] 0 0
HET M #5 Salivary gland [MA:0000346] 0 0
HET F #7 Salivary gland [MA:0000346] 0 0
HET F #2 Lung [MA:0000415] 0 0
HOM M #3 Bone marrow [MA:0000134] 0 0
HET F #7 Thyroid 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM F #8 Eye [MA:0000261] 0 0
HOM M #3 Stomach [MA:0000353] 0 0
HOM F #8 Large intestine [MA:0000333] 0 0
HET M #5 Mammary gland [MA:0000145] Not applicable
HET F #7 Thymus [MA:0000142] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM M #3 Gall bladder [MA:0000356] 0 0
HET M #6 Tooth [MA:0000348] 0 0
HOM F #1 Gall bladder [MA:0000356] 0 0
HET F #7 Urinary bladder [MA:0000380] 0 0
HET F #2 Liver [MA:0000358] 0 0
HOM F #8 Salivary gland [MA:0000346] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HET F #7 Mammary gland [MA:0000145] 0 0
HOM M #3 Tooth [MA:0000348] 0 0
HET M #6 Stomach [MA:0000353] 0 0
HET M #6 Gall bladder [MA:0000356] 0 0

Associated histopathology images

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