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Histopathology data for Fzd1

Home Genes Fzd1 Histopathology

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #4 Stomach [MA:0000353] 1 0 Stomach, glandular: Focal, gland ectasia
HOM F #2 Skeletal muscle [MA:0003148]
HOM F #1 Brown adipose tissue [MA:0000057]
HOM F #2 Esophagus [MA:0000352]
HOM F #1 Thymus [MA:0000142]
HOM F #1 Mammary gland [MA:0000145]
HOM F #2 Skin [MA:0000151]
HOM M #3 Bone [MA:0001459]
HOM F #2 Bone marrow [MA:0000134]
HOM M #4 Sternum [MA:0001331]
HOM M #4 Tongue [MA:0000347]
HOM M #3 Testis [MA:0000411] 1 0 Testis: Rare, late pachytene spermatocyte mitoses
HOM F #2 Heart [MA:0000072]
HOM M #4 Lung [MA:0000415]
HOM M #3 Tooth [MA:0000348]
HOM M #3 Trigeminal V ganglion [MA:0001080]
HOM M #3 Knee joint [MA:0000471]
HOM M #3 Salivary gland [MA:0000346]
HOM F #1 Small intestine [MA:0000337]
HOM M #4 Skin [MA:0000151]
HOM F #2 Uterus [MA:0000389]
HOM F #1 Pancreas [MA:0000120]
HOM F #2 Trachea [MA:0000441]
HOM M #4 Skeletal muscle [MA:0003148]
HOM F #2 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical and follicular lymphoid hyperplasia
HOM M #4 Kidney [MA:0000368]
HOM M #4 Heart [MA:0000072]
HOM M #3 Trachea [MA:0000441]
HOM M #3 Tibia [MA:0001361]
HOM F #2 Tongue [MA:0000347]
HOM M #3 Liver [MA:0000358] 1 0 Liver: Minimal, focal, extramedullary hematopoiesis
HOM M #3 Nasal cavity [MA:0000284]
HOM M #4 Ear [MA:0000236]
HOM F #2 Brain [MA:0000168]
HOM M #4 Spleen [MA:0000141]
HOM M #4 Large intestine [MA:0000333]
HOM M #3 Lymph node [MA:0000139] 2 0 Lymph node, mesenteric: Moderate, paracortical and follicular lymphoid hyperplasia with sinus histiocytosis
HOM F #2 Lung [MA:0000415]
HOM F #1 Spinal cord [MA:0000216]
HOM F #2 Nasal cavity [MA:0000284]
HOM F #2 Stomach [MA:0000353]
HOM F #1 Ovary [MA:0000384]
HOM F #1 Femur [MA:0001359]
HOM M #4 Lymph node [MA:0000139] 1 0 Lymph node, peripancreatic: Mild, paracortical and follicular lymphoid hyperplasia Lymph node, mesenteric: Mild, lymphoid hyperplasia
HOM F #2 Urinary bladder [MA:0000380]
HOM F #2 Bone [MA:0001459]
HOM F #1 Urinary bladder [MA:0000380]
HOM F #1 Bone [MA:0001459]
HOM F #2 Ovary [MA:0000384]
HOM F #2 Salivary gland [MA:0000346]
HOM M #3 Thymus [MA:0000142]
HOM F #1 Adrenal gland [MA:0000116]
HOM F #1 Spleen [MA:0000141]
HOM M #4 Bone marrow [MA:0000134]
HOM M #4 Sciatic nerve [MA:0001172]
HOM F #1 Trigeminal V ganglion [MA:0001080]
HOM F #1 Salivary gland [MA:0000346]
HOM M #4 Brown adipose tissue [MA:0000057]
HOM M #3 Gall bladder [MA:0000356]
HOM M #4 Small intestine [MA:0000337]
HOM M #4 Salivary gland [MA:0000346]
HOM M #3 Thyroid
HOM M #3 Femur [MA:0001359]
HOM M #4 Adrenal gland [MA:0000116]
HOM M #4 Esophagus [MA:0000352]
HOM F #2 Sciatic nerve [MA:0001172]
HOM M #4 Brain [MA:0000168]
HOM F #1 Lymph node [MA:0000139] 2 0 Lymph node, mandibular: Moderate, paracortical lymphoid hyperplasia Lymph node, mesenteric: Mild paracortical and follicular lymphoid hyperplasia with mild lymphocytolysis and sinus histiocytosis
HOM F #2 Large intestine [MA:0000333]
HOM M #4 Seminal vesicle [MA:0000410]
HOM M #4 Bone [MA:0001459]
HOM M #3 Eye [MA:0000261]
HOM F #2 Ear [MA:0000236]
HOM F #1 Tongue [MA:0000347]
HOM F #1 Tibia [MA:0001361]
HOM M #3 Spinal cord [MA:0000216]
HOM M #3 Skeletal muscle [MA:0003148]
HOM M #4 Testis [MA:0000411]
HOM M #4 Urinary bladder [MA:0000380]
HOM M #3 Epididymis [MA:0000397]
HOM M #3 Skin [MA:0000151]
HOM F #1 Kidney [MA:0000368]
HOM M #3 Pancreas [MA:0000120]
HOM M #4 Prostate gland [MA:0000404]
HOM F #2 Small intestine [MA:0000337]
HOM F #1 Skeletal muscle [MA:0003148]
HOM F #1 Esophagus [MA:0000352]
HOM M #3 Kidney [MA:0000368]
HOM M #3 Sternum [MA:0001331]
HOM M #3 Adrenal gland [MA:0000116]
HOM M #3 Spleen [MA:0000141]
HOM M #3 Seminal vesicle [MA:0000410]
HOM F #2 Brown adipose tissue [MA:0000057]
HOM F #1 Uterus [MA:0000389]
HOM F #1 Ear [MA:0000236]
HOM F #1 Brain [MA:0000168]
HOM M #3 Large intestine [MA:0000333]
HOM F #2 Liver [MA:0000358]
HOM F #2 Tibia [MA:0001361]
HOM M #3 Urinary bladder [MA:0000380]
HOM M #4 Pancreas [MA:0000120]
HOM F #2 Thymus [MA:0000142]
HOM F #2 Mammary gland [MA:0000145]
HOM M #3 Lung [MA:0000415]
HOM F #1 Gall bladder [MA:0000356]
HOM F #1 Thyroid
HOM M #4 Liver [MA:0000358]
HOM M #3 Stomach [MA:0000353]
HOM M #4 Tibia [MA:0001361]
HOM M #4 Trigeminal V ganglion [MA:0001080]
HOM F #1 Sciatic nerve [MA:0001172]
HOM M #3 Heart [MA:0000072]
HOM F #1 Skin [MA:0000151]
HOM F #1 Bone marrow [MA:0000134]
HOM F #1 Eye [MA:0000261]
HOM F #1 Sternum [MA:0001331]
HOM M #3 Tongue [MA:0000347]
HOM F #2 Adrenal gland [MA:0000116]
HOM F #1 Tooth [MA:0000348]
HOM M #4 Spinal cord [MA:0000216]
HOM M #3 Esophagus [MA:0000352]
HOM M #3 Bone marrow [MA:0000134]
HOM F #2 Knee joint [MA:0000471]
HOM M #4 Trachea [MA:0000441]
HOM F #2 Tooth [MA:0000348]
HOM M #4 Nasal cavity [MA:0000284]
HOM F #2 Kidney [MA:0000368]
HOM M #4 Thyroid
HOM M #4 Gall bladder [MA:0000356]
HOM F #2 Spleen [MA:0000141]
HOM F #2 Sternum [MA:0001331]
HOM M #3 Small intestine [MA:0000337]
HOM M #3 Brain [MA:0000168]
HOM M #4 Femur [MA:0001359]
HOM M #3 Ear [MA:0000236]
HOM M #4 Eye [MA:0000261] 1 0 Eye: Mild, focal retinal dysplasia
HOM F #1 Large intestine [MA:0000333]
HOM F #1 Knee joint [MA:0000471]
HOM M #4 Epididymis [MA:0000397] 1 0 Epididymis, unilateral: Mild, luminal cellular debris
HOM M #3 Prostate gland [MA:0000404]
HOM F #1 Trachea [MA:0000441]
HOM M #4 Knee joint [MA:0000471]
HOM F #2 Spinal cord [MA:0000216]
HOM F #1 Nasal cavity [MA:0000284]
HOM F #2 Femur [MA:0001359]
HOM M #4 Thymus [MA:0000142]
HOM F #1 Stomach [MA:0000353]
HOM F #1 Lung [MA:0000415]
HOM F #2 Pancreas [MA:0000120]
HOM F #2 Eye [MA:0000261]
HOM F #1 Heart [MA:0000072]
HOM F #2 Trigeminal V ganglion [MA:0001080]
HOM F #1 Liver [MA:0000358]
HOM F #2 Gall bladder [MA:0000356]
HOM F #2 Thyroid
HOM M #3 Brown adipose tissue [MA:0000057]
HOM M #4 Tooth [MA:0000348]
HOM M #3 Sciatic nerve [MA:0001172]

Associated histopathology images

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