Histopathology data for Fmnl2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #1 Esophagus [MA:0000352] 0 0
HOM F #1 Large intestine [MA:0000333] 0 0
HOM M #3 Liver [MA:0000358] 0 0
HOM F #1 Femur [MA:0001359] 0 0
HOM F #4 Sciatic nerve [MA:0001172] 0 0
HOM F #4 Lymph node [MA:0000139] 0 0
HOM F #1 Kidney [MA:0000368] 0 0
HOM F #1 Thymus [MA:0000142] 0 0
HOM M #2 Mammary gland [MA:0000145] Not applicable
HOM F #4 Sternum [MA:0001331] 0 0
HOM F #4 Adrenal gland [MA:0000116] 0 0
HOM M #2 Ovary [MA:0000384] Not applicable
HOM F #1 Bone marrow [MA:0000134] 0 0
HOM F #1 Thyroid 0 0
HOM M #3 Tongue [MA:0000347] 0 0
HOM M #3 Skin [MA:0000151] 0 0
HOM F #1 Lymph node [MA:0000139] 0 0
HOM F #4 Pancreas [MA:0000120] 0 0
HOM F #1 Eye [MA:0000261] 1 0 multi-localised chronic Retinal dysplasia.
HOM M #2 Trachea [MA:0000441] 0 0
HOM F #4 Prostate gland [MA:0000404] Not applicable
HOM F #1 Small intestine [MA:0000337] 0 0
HOM M #2 Spinal cord [MA:0000216] 0 0
HOM M #3 Optic II nerve [MA:0001097] 0 0
HOM F #1 Optic II nerve [MA:0001097] 0 0
HOM M #2 Seminal vesicle [MA:0000410] 0 0
HOM F #1 Sciatic nerve [MA:0001172] 0 0
HOM F #4 Thyroid 0 0
HOM M #2 Spleen [MA:0000141] 0 0
HOM F #4 Kidney [MA:0000368] 0 0
HOM M #3 Small intestine [MA:0000337] 0 0
HOM M #2 Gall bladder [MA:0000356] 0 0
HOM F #4 Trachea [MA:0000441] 0 0
HOM M #3 Skeletal muscle [MA:0003148] 0 0
HOM M #3 Femur [MA:0001359] 0 0
HOM F #1 Pancreas [MA:0000120] 0 0
HOM F #4 Bone marrow [MA:0000134] 0 0
HOM M #2 Tongue [MA:0000347] 0 0
HOM F #1 Skin [MA:0000151] 0 0
HOM M #3 Thymus [MA:0000142] 0 0
HOM M #3 Eye [MA:0000261] 1 0 chronic multi-localised Retinal dysplasia.
HOM F #4 Heart [MA:0000072] 0 0
HOM M #3 Large intestine [MA:0000333] 0 0
HOM M #2 Prostate gland [MA:0000404] 0 0
HOM F #4 Spinal cord [MA:0000216] 0 0
HOM M #2 Adrenal gland [MA:0000116] 0 0
HOM F #1 Spinal cord [MA:0000216] 0 0
HOM F #4 Spleen [MA:0000141] 0 0
HOM M #3 Sciatic nerve [MA:0001172] 0 0
HOM M #2 Sternum [MA:0001331] 0 0
HOM M #3 Lymph node [MA:0000139] 0 0
HOM F #1 Urinary bladder [MA:0000380] 0 0
HOM M #2 Liver [MA:0000358] 0 0
HOM M #2 Lung [MA:0000415] 0 0
HOM F #4 Small intestine [MA:0000337] 0 0
HOM M #3 Adrenal gland [MA:0000116] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #1 Uterus [MA:0000389] 0 0
HOM F #1 Testis [MA:0000411] Not applicable
HOM F #1 Salivary gland [MA:0000346] 0 0
HOM M #3 Bone marrow [MA:0000134] 0 0
HOM M #2 Heart [MA:0000072] 0 0
HOM F #4 Liver [MA:0000358] 0 0
HOM F #4 Thymus [MA:0000142] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM M #2 Lymph node [MA:0000139] 0 0
HOM F #4 Femur [MA:0001359] 3 0 chronic localized Skeletal fibroma (fibrous cortical defect).
HOM M #3 Lung [MA:0000415] 0 0
HOM M #3 Trachea [MA:0000441] 0 0
HOM F #4 Eye [MA:0000261] 0 0
HOM M #2 Epididymis [MA:0000397] 0 0
HOM M #3 Sternum [MA:0001331] 3 0 localized chronic Sternal segment dislocation
HOM F #1 Brain [MA:0000168] 0 0
HOM M #2 Bone marrow [MA:0000134] 0 0
HOM F #4 Uterus [MA:0000389] 0 0
HOM F #4 Brain [MA:0000168] 0 0
HOM M #3 Gall bladder [MA:0000356] 0 0
HOM F #1 Mammary gland [MA:0000145] 0 0
HOM M #3 Spleen [MA:0000141] 0 0
HOM F #4 Lung [MA:0000415] 0 0
HOM M #3 Urinary bladder [MA:0000380] 0 0
HOM M #3 Epididymis [MA:0000397] 0 0
HOM M #2 Femur [MA:0001359] 0 0
HOM M #2 Kidney [MA:0000368] 0 0
HOM M #2 Thyroid 0 0
HOM F #4 Skeletal muscle [MA:0003148] 0 0
HOM F #4 Salivary gland [MA:0000346] 0 0
HOM M #2 Optic II nerve [MA:0001097] 0 0
HOM M #2 Thymus [MA:0000142] 0 0
HOM M #3 Prostate gland [MA:0000404] 0 0
HOM M #2 Eye [MA:0000261] 0 0
HOM M #3 Heart [MA:0000072] 1 0 localized chronic Right ventricular epicardial fibrosis, focal
HOM F #4 Tongue [MA:0000347] 0 0
HOM F #1 Stomach [MA:0000353] 0 0
HOM M #3 Spinal cord [MA:0000216] 0 0
HOM F #1 Skeletal muscle [MA:0003148] 0 0
HOM F #4 Skin [MA:0000151] 0 0
HOM M #2 Sciatic nerve [MA:0001172] 0 0
HOM F #1 Seminal vesicle [MA:0000410] Not applicable
HOM M #2 Small intestine [MA:0000337] 0 0
HOM F #1 Tongue [MA:0000347] 0 0
HOM M #2 Skin [MA:0000151] 0 0
HOM M #3 Pancreas [MA:0000120] 0 0
HOM M #2 Large intestine [MA:0000333] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable
HOM F #1 Gall bladder [MA:0000356] 0 0
HOM M #3 Seminal vesicle [MA:0000410] 0 0
HOM F #4 Testis [MA:0000411] Not applicable
HOM F #1 Spleen [MA:0000141] 0 0
HOM F #4 Ovary [MA:0000384] 0 0
HOM M #2 Pancreas [MA:0000120] 0 0
HOM F #1 Epididymis [MA:0000397] Not applicable
HOM M #3 Esophagus [MA:0000352] 0 0
HOM F #1 Liver [MA:0000358] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM M #2 Skeletal muscle [MA:0003148] 0 0
HOM M #3 Stomach [MA:0000353] 0 0
HOM M #3 Kidney [MA:0000368] 0 0
HOM M #3 Thyroid 0 0
HOM M #3 Uterus [MA:0000389] Not applicable
HOM F #1 Trachea [MA:0000441] 0 0
HOM M #2 Testis [MA:0000411] 0 0
HOM F #1 Prostate gland [MA:0000404] Not applicable
HOM F #4 Gall bladder [MA:0000356] 0 0
HOM M #3 Salivary gland [MA:0000346] 0 0
HOM M #3 Testis [MA:0000411] 0 0
HOM F #1 Sternum [MA:0001331] 0 0
HOM F #1 Ovary [MA:0000384] 0 0
HOM M #2 Salivary gland [MA:0000346] 0 0
HOM F #1 Heart [MA:0000072] 0 0
HOM F #4 Esophagus [MA:0000352] 0 0
HOM M #2 Urinary bladder [MA:0000380] 0 0
HOM F #4 Large intestine [MA:0000333] 0 0
HOM M #2 Stomach [MA:0000353] 0 0
HOM F #4 Mammary gland [MA:0000145] 0 0
HOM F #1 Lung [MA:0000415] 0 0
HOM M #2 Brain [MA:0000168] 0 0
HOM F #1 Adrenal gland [MA:0000116] 0 0
HOM M #2 Uterus [MA:0000389] Not applicable
HOM M #2 Esophagus [MA:0000352] 0 0
HOM M #3 Brain [MA:0000168] 0 0
HOM F #4 Optic II nerve [MA:0001097] 0 0
HOM F #4 Stomach [MA:0000353] 0 0
HOM F #4 Urinary bladder [MA:0000380] 0 0

Associated histopathology images

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