Histopathology data for Fbxw9

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #8 Sciatic nerve [MA:0001172] 0 0
HET M #1 Epididymis [MA:0000397] 0 0
HET M #2 Seminal vesicle [MA:0000410] 0 0
HET M #2 Stomach [MA:0000353] 0 0
HET M #1 Prostate gland [MA:0000404] 0 0
HOM M #6 Trachea [MA:0000441] 0 0
HET F #7 Uterus [MA:0000389] 0 0
HET M #1 Large intestine [MA:0000333] 0 0
HOM M #8 Adrenal gland [MA:0000116] 0 0
HOM F #4 Small intestine [MA:0000337] 0 0
HET M #2 Testis [MA:0000411] 0 0
HOM M #8 Bone marrow [MA:0000134] 0 0
HET F #7 Optic II nerve [MA:0001097] 0 0
HOM M #8 Testis [MA:0000411] 0 0
HET F #7 Brain [MA:0000168] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HET M #2 Uterus [MA:0000389] Not applicable
HET M #2 Brain [MA:0000168] 0 0
HET F #7 Heart [MA:0000072] 0 0
HOM M #6 Liver [MA:0000358] 0 0
HET F #5 Esophagus [MA:0000352] 0 0
HOM M #8 Optic II nerve [MA:0001097] 0 0
HET F #5 Sciatic nerve [MA:0001172] 0 0
HET F #7 Thymus [MA:0000142] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HET F #7 Stomach [MA:0000353] 0 0
HOM M #6 Epididymis [MA:0000397] 0 0
HET F #7 Trachea [MA:0000441] 0 0
HET F #7 Eye [MA:0000261] 0 0
HET M #1 Pancreas [MA:0000120] 0 0
HET F #7 Testis [MA:0000411] Not applicable
HET M #2 Optic II nerve [MA:0001097] 0 0
HET M #2 Spleen [MA:0000141] 0 0
HOM M #6 Seminal vesicle [MA:0000410] 0 0
HOM M #6 Adrenal gland [MA:0000116] 0 0
HOM M #8 Mammary gland [MA:0000145] Not applicable
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #8 Liver [MA:0000358] 0 0
HOM M #8 Skin [MA:0000151] 0 0
HOM F #4 Mammary gland [MA:0000145] 0 0
HET M #2 Gall bladder [MA:0000356] 0 0
HET F #5 Skeletal muscle [MA:0003148] 0 0
HET M #2 Femur [MA:0001359] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM F #4 Bone marrow [MA:0000134] 0 0
HET F #5 Ovary [MA:0000384] 0 0
HOM F #4 Testis [MA:0000411] Not applicable
HET M #2 Heart [MA:0000072] 0 0
HOM M #6 Skin [MA:0000151] 0 0
HOM M #6 Lymph node [MA:0000139] 0 0
HET M #2 Pancreas [MA:0000120] 0 0
HET F #7 Gall bladder [MA:0000356] 0 0
HET M #1 Liver [MA:0000358] 0 0
HOM F #4 Optic II nerve [MA:0001097] 0 0
HOM M #8 Seminal vesicle [MA:0000410] 0 0
HOM F #4 Spleen [MA:0000141] 0 0
HOM M #8 Esophagus [MA:0000352] 0 0
HET F #5 Mammary gland [MA:0000145] 0 0
HOM M #6 Knee joint [MA:0000471] 0 0
HET F #7 Spleen [MA:0000141] 0 0
HET M #2 Esophagus [MA:0000352] 0 0
HET M #2 Large intestine [MA:0000333] 0 0
HET M #2 Eye [MA:0000261] chronic localized Persistent hyaloid artery.
HET M #1 Lung [MA:0000415] 0 0
HET M #2 Trachea [MA:0000441] 0 0
HET M #2 Thymus [MA:0000142] 0 0
HET F #5 Lymph node [MA:0000139] 0 0
HOM M #6 Testis [MA:0000411] 0 0
HET F #7 Femur [MA:0001359] 0 0
HOM F #4 Ovary [MA:0000384] 0 0
HOM F #4 Gall bladder [MA:0000356] 0 0
HOM F #4 Brain [MA:0000168] 0 0
HOM M #6 Esophagus [MA:0000352] 0 0
HET F #7 Prostate gland [MA:0000404] Not applicable
HOM M #8 Femur [MA:0001359] 0 0
HET F #5 Seminal vesicle [MA:0000410] Not applicable
HOM F #4 Kidney [MA:0000368] 0 0
HOM M #8 Salivary gland [MA:0000346] 0 0
HET F #5 Thymus [MA:0000142] 0 0
HOM F #3 Spleen [MA:0000141] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM M #8 Spinal cord [MA:0000216] 0 0
HOM M #8 Heart [MA:0000072] 0 0
HET F #5 Trachea [MA:0000441] 0 0
HET F #5 Eye [MA:0000261] 0 0
HET M #1 Bone marrow [MA:0000134] 0 0
HET M #1 Optic II nerve [MA:0001097] 0 0
HET M #1 Spleen [MA:0000141] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM F #4 Trachea [MA:0000441] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HET F #5 Kidney [MA:0000368] 0 0
HET M #1 Spinal cord [MA:0000216] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM M #8 Small intestine [MA:0000337] 0 0
HET F #7 Skeletal muscle [MA:0003148] 0 0
HOM M #6 Prostate gland [MA:0000404] 0 0
HET M #2 Prostate gland [MA:0000404] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HET F #5 Uterus [MA:0000389] 0 0
HOM M #8 Spleen [MA:0000141] 0 0
HOM M #6 Small intestine [MA:0000337] 0 0
HOM M #8 Skeletal muscle [MA:0003148] 0 0
HET M #2 Mammary gland [MA:0000145] Not applicable
HET M #1 Testis [MA:0000411] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM M #8 Lymph node [MA:0000139] 0 0
HET M #1 Brain [MA:0000168] 0 0
HET F #7 Esophagus [MA:0000352] 0 0
HET M #2 Ovary [MA:0000384] Not applicable
HOM F #3 Thyroid 0 0
HOM M #6 Stomach [MA:0000353] 0 0
HET M #1 Sciatic nerve [MA:0001172] 0 0
HOM M #6 Bone marrow [MA:0000134] 0 0
HOM M #6 Tibia [MA:0001361] 0 0
HOM M #8 Prostate gland [MA:0000404] 0 0
HOM F #4 Adrenal gland [MA:0000116] 0 0
HOM M #6 Optic II nerve [MA:0001097] 0 0
HET M #2 Skeletal muscle [MA:0003148] 0 0
HOM M #6 Spinal cord [MA:0000216] 0 0
HOM M #6 Spleen [MA:0000141] 0 0
HET F #5 Skin [MA:0000151] 0 0
HOM M #8 Epididymis [MA:0000397] 0 0
HOM F #4 Urinary bladder [MA:0000380] 0 0
HOM M #8 Pancreas [MA:0000120] 0 0
HET F #5 Small intestine [MA:0000337] 0 0
HOM M #6 Femur [MA:0001359] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HET F #5 Femur [MA:0001359] 0 0
HET M #1 Thyroid 0 0
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM M #6 Skeletal muscle [MA:0003148] 0 0
HET M #1 Stomach [MA:0000353] 0 0
HOM M #6 Salivary gland [MA:0000346] 0 0
HET F #7 Seminal vesicle [MA:0000410] Not applicable
HET M #2 Bone marrow [MA:0000134] 0 0
HET M #1 Gall bladder [MA:0000356] 0 0
HET F #7 Ovary [MA:0000384] 0 0
HET M #2 Liver [MA:0000358] 0 0
HET F #7 Salivary gland [MA:0000346] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM M #6 Heart [MA:0000072] 0 0
HOM M #6 Pancreas [MA:0000120] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HET F #5 Heart [MA:0000072] 0 0
HOM M #8 Stomach [MA:0000353] 0 0
HET M #1 Adrenal gland [MA:0000116] 0 0
HOM F #4 Large intestine [MA:0000333] 0 0
HET F #7 Mammary gland [MA:0000145] 0 0
HET F #7 Urinary bladder [MA:0000380] 0 0
HET M #2 Thyroid 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HET M #2 Spinal cord [MA:0000216] 0 0
HET F #7 Knee joint [MA:0000471] 0 0
HOM M #6 Thyroid 0 0
HOM M #8 Urinary bladder [MA:0000380] 0 0
HET F #7 Bone marrow [MA:0000134] 0 0
HET M #1 Small intestine [MA:0000337] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HET F #5 Large intestine [MA:0000333] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM M #8 Thymus [MA:0000142] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HET M #2 Kidney [MA:0000368] 0 0
HOM F #4 Knee joint [MA:0000471] 0 0
HET M #2 Tibia [MA:0001361] 0 0
HOM M #6 Thymus [MA:0000142] 0 0
HET M #2 Knee joint [MA:0000471] 0 0
HET F #5 Prostate gland [MA:0000404] Not applicable
HOM M #8 Thyroid 0 0
HET F #7 Spinal cord [MA:0000216] 0 0
HOM M #6 Gall bladder [MA:0000356] 0 0
HOM F #4 Pancreas [MA:0000120] 0 0
HOM M #6 Ovary [MA:0000384] Not applicable
HOM F #3 Testis [MA:0000411] Not applicable
HOM M #6 Brain [MA:0000168] 0 0
HET F #7 Liver [MA:0000358] 1 0 chronic multi-localised Inflammatory cell aggregates.
HET M #1 Skeletal muscle [MA:0003148] 0 0
HOM F #4 Heart [MA:0000072] 0 0
HET M #2 Salivary gland [MA:0000346] 0 0
HOM F #4 Eye [MA:0000261] 0 0
HET F #7 Kidney [MA:0000368] 0 0
HOM M #8 Uterus [MA:0000389] Not applicable
HET M #1 Lymph node [MA:0000139] 0 0
HOM M #8 Gall bladder [MA:0000356] 0 0
HOM M #8 Brain [MA:0000168] 0 0
HET F #5 Salivary gland [MA:0000346] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HET M #1 Mammary gland [MA:0000145] Not applicable
HOM M #8 Eye [MA:0000261] 0 0
HET F #5 Liver [MA:0000358] 0 0
HOM M #6 Lung [MA:0000415] 0 0
HET M #2 Skin [MA:0000151] 0 0
HET M #1 Ovary [MA:0000384] Not applicable
HET M #2 Adrenal gland [MA:0000116] 0 0
HET F #7 Thyroid 0 0
HET F #5 Epididymis [MA:0000397] Not applicable
HET F #5 Urinary bladder [MA:0000380] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM F #4 Thymus [MA:0000142] 0 0
HOM M #8 Lung [MA:0000415] 0 0
HET F #5 Bone marrow [MA:0000134] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM M #6 Uterus [MA:0000389] Not applicable
HOM F #3 Epididymis [MA:0000397] Not applicable
HET F #7 Skin [MA:0000151] 0 0
HET F #7 Adrenal gland [MA:0000116] 0 0
HOM M #8 Ovary [MA:0000384] Not applicable
HOM F #3 Large intestine [MA:0000333] 0 0
HET F #7 Small intestine [MA:0000337] 0 0
HOM F #4 Lung [MA:0000415] 0 0
HET F #5 Lung [MA:0000415] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HET F #5 Thyroid 0 0
HET M #1 Urinary bladder [MA:0000380] 0 0
HET F #5 Spinal cord [MA:0000216] 0 0
HET F #5 Stomach [MA:0000353] 0 0
HOM F #4 Liver [MA:0000358] 0 0
HOM M #6 Eye [MA:0000261] multi-localised chronic Retinal dysplasia.
HOM F #3 Ovary [MA:0000384] 0 0
HET M #1 Trachea [MA:0000441] 0 0
HET F #5 Testis [MA:0000411] Not applicable
HOM F #3 Lymph node [MA:0000139] 0 0
HET F #7 Lung [MA:0000415] 0 0
HET M #1 Thymus [MA:0000142] 0 0
HET M #1 Salivary gland [MA:0000346] 0 0
HOM F #4 Thyroid 0 0
HOM F #4 Uterus [MA:0000389] 0 0
HET M #1 Seminal vesicle [MA:0000410] 0 0
HOM M #6 Large intestine [MA:0000333] 0 0
HET F #5 Pancreas [MA:0000120] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #4 Skeletal muscle [MA:0003148] 0 0
HET F #5 Optic II nerve [MA:0001097] 0 0
HOM F #4 Esophagus [MA:0000352] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HET F #5 Spleen [MA:0000141] 0 0
HET F #5 Brain [MA:0000168] 0 0
HOM F #3 Esophagus [MA:0000352] 0 0
HET M #1 Uterus [MA:0000389] Not applicable
HET F #7 Large intestine [MA:0000333] 0 0
HET M #2 Small intestine [MA:0000337] 0 0
HET F #7 Epididymis [MA:0000397] Not applicable
HOM M #6 Mammary gland [MA:0000145] Not applicable
HET F #7 Tibia [MA:0001361] 0 0
HET M #1 Kidney [MA:0000368] 0 0
HOM M #8 Trachea [MA:0000441] 0 0
HET F #7 Pancreas [MA:0000120] 0 0
HET M #1 Esophagus [MA:0000352] 0 0
HET F #5 Adrenal gland [MA:0000116] 0 0
HOM F #4 Tibia [MA:0001361] 0 0
HOM F #4 Stomach [MA:0000353] 0 0
HOM F #4 Skin [MA:0000151] 0 0
HOM F #4 Femur [MA:0001359] 0 0
HET M #2 Lung [MA:0000415] 0 0
HET M #1 Eye [MA:0000261] 0 0
HOM M #8 Kidney [MA:0000368] 0 0
HOM M #6 Urinary bladder [MA:0000380] 0 0
HOM F #4 Lymph node [MA:0000139] 0 0
HET F #7 Lymph node [MA:0000139] 0 0
HET M #2 Urinary bladder [MA:0000380] 0 0
HET M #2 Epididymis [MA:0000397] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM F #4 Salivary gland [MA:0000346] 0 0
HET M #2 Lymph node [MA:0000139] 0 0
HET M #1 Femur [MA:0001359] 0 0
HOM F #4 Prostate gland [MA:0000404] Not applicable
HOM M #8 Large intestine [MA:0000333] 0 0
HET M #1 Heart [MA:0000072] 0 0
HOM F #3 Brain [MA:0000168] 0 0
HET M #1 Skin [MA:0000151] 0 0
HOM M #6 Kidney [MA:0000368] 0 0
HET F #5 Gall bladder [MA:0000356] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #4 Spinal cord [MA:0000216] 0 0

Associated histopathology images

Fbxw9
heterozygote
Eye - MA term MA:0000261
Fbxw9tm1b(EUCOMM)Wtsi
experimental
Fbxw9
heterozygote
Liver - MA term MA:0000358
Fbxw9tm1b(EUCOMM)Wtsi
experimental
Fbxw9
heterozygote
Liver - MA term MA:0000358
Fbxw9tm1b(EUCOMM)Wtsi
experimental

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter