Histopathology data for Elp1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HET M #1 Liver [MA:0000358] lipid deposition [MPATH:42] 3 0 steatosis MPATH:622 distributed Hepatic lipidosis, severe
HET M #1 Prostate normal [MPATH:458] 0 0
HET F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET M #4 Testes normal [MPATH:458] 0 0
HET F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HET M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET F #3 Thyroid normal [MPATH:458] 0 0
HET F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #3 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 steatosis MPATH:622 multi-localised Moderate hepatic steatosis
HET F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HET M #1 Eye with optic nerve normal [MPATH:458] 0 0
HET F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #1 Thyroid normal [MPATH:458] 0 0
HET M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET F #3 Eye with optic nerve normal [MPATH:458] 0 0
HET M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HET M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HET M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HET M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET M #4 Eye with optic nerve normal [MPATH:458] 0 0
HET F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HET F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HET M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #4 Prostate normal [MPATH:458] 0 0
HET F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #4 Thyroid normal [MPATH:458] 0 0
HET F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HET M #4 Liver [MA:0000358] lipid deposition [MPATH:42] 3 0 steatosis MPATH:622 distributed Hepatic lipidosis, severe
HET M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET F #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HET M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HET M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET M #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HET F #3 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 lymphoid hyperplasia MPATH:147 subacute distributed Lymphoid hyperplasia.
HET F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HET M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HET M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HET F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HET F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HET M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HET M #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HET M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #2 Eye with optic nerve normal [MPATH:458] 0 0
HET F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HET M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HET F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HET M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HET F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HET M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HET F #2 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 steatosis MPATH:622 multi-localised Moderate hepatic steatosis
HET F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HET M #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HET M #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET F #2 Thyroid normal [MPATH:458] 0 0
HET F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #1 Testes normal [MPATH:458] 0 0
HET M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HET M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HET F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HET M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HET F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HET F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HET M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HET F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HET M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HET F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HET M #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HET M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0

Associated histopathology images

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