Histopathology data for Dact2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Prostate Not applicable
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #1 Testes Not applicable
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM F #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM M #3 Uterus [MA:0000389] Not applicable
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM F #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Testes normal [MPATH:458] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Epididymis [MA:0000397] Not applicable
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM F #1 Thyroid normal [MPATH:458] 0 0
HOM F #2 Testes Not applicable
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #1 Prostate Not applicable
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #1 Seminal vesicle [MA:0000410] Not applicable
HOM F #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #4 Prostate normal [MPATH:458] 0 0
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #4 Thyroid normal [MPATH:458] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #1 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #1 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #4 Testes normal [MPATH:458] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable

Associated histopathology images

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter