Histopathology data for Clmn

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM F #3 Spleen [MA:0000141] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM M #4 Salivary gland [MA:0000346] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM F #3 Ovary [MA:0000384] 0 0
HOM F #2 Mammary gland [MA:0000145] 0 0
HOM M #1 Salivary gland [MA:0000346] 0 0
HOM M #4 Tongue [MA:0000347] 0 0
HOM F #3 Heart [MA:0000072] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM M #1 Uterus [MA:0000389] Not applicable
HOM M #1 Lung [MA:0000415] 0 0
HOM M #4 Brain [MA:0000168] 0 0
HOM M #4 Nasal cavity [MA:0000284] 0 0
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM M #1 Stomach [MA:0000353] 0 0
HOM F #2 Urinary bladder [MA:0000380] 0 0
HOM M #1 Testis [MA:0000411] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM M #1 Heart [MA:0000072] 0 0
HOM F #3 Prostate gland [MA:0000404] Not applicable
HOM F #2 Stomach [MA:0000353] 0 0
HOM M #4 Liver [MA:0000358] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM F #2 Heart [MA:0000072] 0 0
HOM F #3 Sternum [MA:0001331] 0 0
HOM F #2 Salivary gland [MA:0000346] 0 0
HOM M #4 Stomach [MA:0000353] 0 0
HOM M #1 Brain [MA:0000168] 0 0
HOM F #2 Uterus [MA:0000389] 0 0
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM M #4 Optic II nerve [MA:0001097] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM F #3 Lung [MA:0000415] 0 0
HOM M #1 Epididymis [MA:0000397] 0 0
HOM F #3 Brain [MA:0000168] 0 0
HOM F #2 Testis [MA:0000411] Not applicable
HOM M #1 Skin [MA:0000151] 0 0
HOM M #1 Spinal cord [MA:0000216] 0 0
HOM M #1 Liver [MA:0000358] 0 0
HOM F #3 Stomach [MA:0000353] 0 0
HOM F #2 Brain [MA:0000168] 1 0 localized Hypocamppal commissure dermoid cyst
HOM F #3 Esophagus [MA:0000352] 0 0
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #3 Uterus [MA:0000389] 0 0
HOM F #3 Sciatic nerve [MA:0001172] 0 0
HOM F #2 Liver [MA:0000358] 0 0
HOM F #3 Salivary gland [MA:0000346] 0 0
HOM F #2 Spinal cord [MA:0000216] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #4 Prostate gland [MA:0000404] 0 0
HOM F #2 Spleen [MA:0000141] 2 0 chronic distributed Erythroid and megakaryocytic hyperplasia
HOM F #3 Tongue [MA:0000347] 0 0
HOM F #3 Nasal cavity [MA:0000284] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Optic II nerve [MA:0001097] 0 0
HOM F #2 Ear [MA:0000236] 0 0
HOM F #2 Skin [MA:0000151] 0 0
HOM M #4 Bone marrow [MA:0000134] 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM M #1 Spleen [MA:0000141] 0 0
HOM M #4 Lung [MA:0000415] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HOM F #2 Thyroid 0 0
HOM M #1 Small intestine [MA:0000337] 0 0
HOM F #2 Kidney [MA:0000368] 0 0
HOM M #4 Sternum [MA:0001331] 2 0 distributed chronic Outward protrusion of the sternal body (pectus carinatum)
HOM M #1 Eye [MA:0000261] 0 0
HOM M #1 Esophagus [MA:0000352] 0 0
HOM M #1 Ear [MA:0000236] 0 0
HOM M #1 Femur [MA:0001359] 0 0
HOM M #4 Lymph node [MA:0000139] 0 0
HOM F #2 Bone marrow [MA:0000134] 0 0
HOM M #1 Thymus [MA:0000142] 0 0
HOM F #2 Optic II nerve [MA:0001097] 0 0
HOM F #2 Small intestine [MA:0000337] 0 0
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM M #1 Thyroid 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM F #2 Femur [MA:0001359] 0 0
HOM M #1 Kidney [MA:0000368] 0 0
HOM F #2 Tooth [MA:0000348] 0 0
HOM M #1 Lymph node [MA:0000139] 0 0
HOM F #3 Skin [MA:0000151] 0 0
HOM F #2 Large intestine [MA:0000333] 0 0
HOM M #4 Sciatic nerve [MA:0001172] 0 0
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #2 Thymus [MA:0000142] 0 0
HOM M #1 Bone marrow [MA:0000134] 0 0
HOM F #3 Bone marrow [MA:0000134] 0 0
HOM F #3 Thyroid 0 0
HOM M #4 Esophagus [MA:0000352] 0 0
HOM M #1 Adrenal gland [MA:0000116] 0 0
HOM M #4 Epididymis [MA:0000397] 0 0
HOM M #4 Eye [MA:0000261] 0 0
HOM M #4 Large intestine [MA:0000333] 0 0
HOM M #4 Thymus [MA:0000142] 0 0
HOM M #1 Sternum [MA:0001331] 2 0 chronic localized Segmental sternum dislocation
HOM M #4 Femur [MA:0001359] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM F #2 Esophagus [MA:0000352] 0 0
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM F #3 Testis [MA:0000411] Not applicable
HOM F #2 Eye [MA:0000261] 0 0
HOM M #1 Tooth [MA:0000348] 0 0
HOM F #3 Tooth [MA:0000348] 0 0
HOM F #2 Lymph node [MA:0000139] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM F #3 Lymph node [MA:0000139] 0 0
HOM F #2 Pancreas [MA:0000120] 0 0
HOM F #2 Tongue [MA:0000347] 0 0
HOM M #1 Seminal vesicle [MA:0000410] 0 0
HOM F #2 Nasal cavity [MA:0000284] 0 0
HOM M #1 Trachea [MA:0000441] 0 0
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM F #3 Eye [MA:0000261] 0 0
HOM F #3 Ear [MA:0000236] 0 0
HOM M #4 Spleen [MA:0000141] 0 0
HOM M #1 Prostate gland [MA:0000404] 0 0
HOM F #2 Adrenal gland [MA:0000116] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM F #2 Skeletal muscle [MA:0003148] 0 0
HOM F #2 Sternum [MA:0001331] 2 0 chronic distributed Outward protrusion of the sternal body (pectus carinatum)
HOM M #1 Urinary bladder [MA:0000380] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM M #4 Ear [MA:0000236] 0 0
HOM M #1 Nasal cavity [MA:0000284] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HOM M #1 Optic II nerve [MA:0001097] 0 0
HOM F #2 Trachea [MA:0000441] 0 0
HOM F #2 Gall bladder [MA:0000356] 0 0
HOM M #4 Tooth [MA:0000348] 0 0
HOM F #2 Lung [MA:0000415] 0 0
HOM M #4 Thyroid 0 0
HOM M #1 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM M #1 Sciatic nerve [MA:0001172] 0 0
HOM M #1 Pancreas [MA:0000120] 0 0
HOM F #2 Ovary [MA:0000384] 0 0
HOM F #2 Prostate gland [MA:0000404] Not applicable
HOM F #2 Sciatic nerve [MA:0001172] 0 0
HOM M #1 Tongue [MA:0000347] 0 0
HOM M #1 Large intestine [MA:0000333] 0 0
HOM M #1 Gall bladder [MA:0000356] 0 0
HOM M #4 Testis [MA:0000411] 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM F #3 Femur [MA:0001359] 0 0
HOM F #3 Liver [MA:0000358] 0 0

Associated histopathology images

Clmn
homozygote
Clmntm1b(EUCOMM)Wtsi
experimental

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