Histopathology data for Camk1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve process of degenerative change [MPATH:14] 3 0 bilateral chronic Retinal degeneration, eye.
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #4 Thyroid normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #1 Seminal vesicle [MA:0000410] Not applicable
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #1 Epididymis [MA:0000397] Not applicable
HOM F #1 Testes Not applicable
HOM M #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Prostate normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #1 Prostate Not applicable
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Mammary gland [MA:0000145] Not applicable
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #4 Testes normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #2 Seminal vesicle [MA:0000410] Not applicable
HOM F #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #4 Mammary gland [MA:0000145] Not applicable
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] inflammation [MPATH:212] 1 0 localized subacute Gastritis, subacute.
HOM F #1 Thyroid normal [MPATH:458] 0 0
HOM F #2 Testes Not applicable
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Epididymis [MA:0000397] Not applicable
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Uterus [MA:0000389] Not applicable
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Testes normal [MPATH:458] 0 0
HOM F #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Ovary [MA:0000384] Not applicable
HOM M #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Ovary [MA:0000384] Not applicable
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #1 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #4 Uterus [MA:0000389] Not applicable
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM F #2 Prostate Not applicable
HOM M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0

Associated histopathology images

Camk1
homozygote
Stomach MA:0000353
MA:0000353 stomach
Camk1tm2b(EUCOMM)Hmgu
experimental
Camk1
homozygote
Eye with optic nerve MA:0000261
MA:0000261 eye
Camk1tm2b(EUCOMM)Hmgu
experimental

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