Histopathology data for Aadac

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #2 Tooth [MA:0000348] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Knee joint [MA:0000471] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Trachea [MA:0000441] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Femur [MA:0001359] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Bone marrow [MA:0000134] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Salivary gland [MA:0000346] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Thyroid normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Tongue [MA:0000347] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Spleen [MA:0000141] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Lung [MA:0000415] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Seminal vesicle [MA:0000410] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Ear [MA:0000236] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Esophagus [MA:0000352] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Thymus [MA:0000142] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Sternum [MA:0001331] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Mammary gland [MA:0000145] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Ovary [MA:0000384] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Kidney [MA:0000368] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Knee joint [MA:0000471] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Bone [MA:0001459] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Brain [MA:0000168] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Testes normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Spleen [MA:0000141] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Tongue [MA:0000347] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Lung [MA:0000415] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Ovary [MA:0000384] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Thymus [MA:0000142] atrophy [MPATH:127] 2 0 distributed Thymic atrophy
HOM F #3 Tibia [MA:0001361] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Spinal cord [MA:0000216] normal [MPATH:458] normal MPATH:458 normal
HOM F #1
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Knee joint [MA:0000471] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Ear [MA:0000236] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Thyroid normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Heart [MA:0000072] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Eye with optic nerve normal [MPATH:458] normal MPATH:458 normal
HOM M #2
HOM F #1 Nasal cavity [MA:0000284] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Eye with optic nerve normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Bone [MA:0001459] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Lung [MA:0000415] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Lymph node [MA:0000139] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Tongue [MA:0000347] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Knee joint [MA:0000471] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Tibia [MA:0001361] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Thymus [MA:0000142] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Thyroid normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Trachea [MA:0000441] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Large intestine [MA:0000333] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Urinary bladder [MA:0000380] fluid accumulation [MPATH:106] dilatation [MPATH:66] 2 0 distention with urine accumulation
HOM M #4 Bone [MA:0001459] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Nasal cavity [MA:0000284] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Small intestine [MA:0000337] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Trachea [MA:0000441] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Mammary gland [MA:0000145] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Sternum [MA:0001331] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Nasal cavity [MA:0000284] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Heart [MA:0000072] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Brain [MA:0000168] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Bone [MA:0001459] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Liver [MA:0000358] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Kidney [MA:0000368] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Skin [MA:0000151] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Sternum [MA:0001331] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Skeletal muscle [MA:0003148] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Pancreas [MA:0000120] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Testes normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Femur [MA:0001359] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Skin [MA:0000151] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Heart [MA:0000072] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Brain [MA:0000168] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Salivary gland [MA:0000346] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Kidney [MA:0000368] necrosis [MPATH:4] 1 0 hydronephrosis MPATH:635 Moderate hydronephrosis with tubular ectasia, minimal proteinosis and medullary tubular epithelial necrosis
HOM M #2 Spleen [MA:0000141] hyperplasia [MPATH:134] 1 0 distributed moderate histiocytosis
HOM M #2 Sciatic nerve [MA:0001172] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Lung [MA:0000415] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Tongue [MA:0000347] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Liver [MA:0000358] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Prostate normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Adrenal gland [MA:0000116] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Tooth [MA:0000348] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Tooth [MA:0000348] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Liver [MA:0000358] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Sternum [MA:0001331] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Liver [MA:0000358] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Eye with optic nerve normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Stomach [MA:0000353] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Eye with optic nerve normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Ear [MA:0000236] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Tibia [MA:0001361] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Uterus [MA:0000389] intracellular and extracellular accumulation [MPATH:33] 1 0 Hydrometra
HOM M #2 Thyroid normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Skin [MA:0000151] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Femur [MA:0001359] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Sciatic nerve [MA:0001172] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Tooth [MA:0000348] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Nasal cavity [MA:0000284] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Uterus [MA:0000389] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Stomach [MA:0000353] hyperplasia [MPATH:134] inflammation [MPATH:212] 1 0 papilloma MPATH:445 focally extensive Squamous papilloma with regional epithelial hyperplasia and gastritis
HOM M #2 Heart [MA:0000072] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Stomach [MA:0000353] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Sciatic nerve [MA:0001172] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Brain [MA:0000168] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Skin [MA:0000151] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Prostate inflammation [MPATH:212] 1 0 Periprostatic pleocellular serositis and steatitis with edema
HOM F #1 Bone marrow [MA:0000134] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Tibia [MA:0001361] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Epididymis [MA:0000397] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Ear [MA:0000236] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Bone marrow [MA:0000134] normal [MPATH:458] normal MPATH:458 normal
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Salivary gland [MA:0000346] normal [MPATH:458] normal MPATH:458 normal
HOM F #1 Sciatic nerve [MA:0001172] normal [MPATH:458] normal MPATH:458 normal
HOM M #2 Gall bladder [MA:0000356] normal [MPATH:458] normal MPATH:458 normal
HOM F #3 Femur [MA:0001359] normal [MPATH:458] normal MPATH:458 normal

Associated histopathology images

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