Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data abnormal neural tube closure Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube closure UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=UC Davis abnormal neural tube morphology Sptan1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=UC Davis abnormal placenta morphology Sptan1 heterozygote male E15.5 Gross Morphology Placenta E14.5-E15.5 Placenta Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_GPO_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GPO_001¶meter_stable_id=IMPC_GPO_002_001&phenotyping_center=UC Davis abnormal placenta morphology Sptan1 homozygote female E15.5 Gross Morphology Placenta E14.5-E15.5 Placenta Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GPO_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GPO_001¶meter_stable_id=IMPC_GPO_002_001&phenotyping_center=UC Davis embryonic growth retardation Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=UC Davis enlarged kidney Sptan1 heterozygote male Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_017_002 microphthalmia Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_002_002 abnormal forebrain development Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Forebrain UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_028_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_028_001&phenotyping_center=UC Davis microcephaly Sptan1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Microcephaly UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_066_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_066_001&phenotyping_center=UC Davis edema Sptan1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Edema UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_064_001&phenotyping_center=UC Davis enlarged spleen Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_016_002 abnormal craniofacial morphology Sptan1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=UC Davis abnormal midbrain development Sptan1 homozygote female E9.5 Gross Morphology Embryo E9.5 Midbrain UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_029_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_029_001&phenotyping_center=UC Davis abnormal eye morphology Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_002_002 preweaning lethality, complete penetrance Sptan1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=UC Davis microphthalmia Sptan1 heterozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Microphthalmia UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_GEO_047_002&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_047_002&phenotyping_center=UC Davis microcephaly Sptan1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Microcephaly UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_066_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_066_001&phenotyping_center=UC Davis abnormal head shape Sptan1 homozygote female E15.5 Gross Morphology Embryo E14.5-E15.5 Head shape UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_015_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_015_001&phenotyping_center=UC Davis preweaning lethality, complete penetrance Sptan1 homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis abnormal neural tube closure Sptan1 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube closure UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_027_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_027_001&phenotyping_center=UC Davis abnormal eye morphology Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_002_002 preweaning lethality, complete penetrance Sptan1 homozygote male Early adult Viability Primary Screen Homozygous males viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=UC Davis abnormal spleen morphology Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_016_002 microphthalmia Sptan1 heterozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Microphthalmia UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_GEO_047_002&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_047_002&phenotyping_center=UC Davis abnormal visceral yolk sac morphology Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Visceral yolk sac morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_018_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_018_001&phenotyping_center=UC Davis edema Sptan1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Edema UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_064_001&phenotyping_center=UC Davis abnormal head shape Sptan1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Head shape UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_015_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_015_001&phenotyping_center=UC Davis abnormal visceral yolk sac morphology Sptan1 homozygote female E9.5 Gross Morphology Embryo E9.5 Visceral yolk sac morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_018_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_018_001&phenotyping_center=UC Davis abnormal midbrain development Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Midbrain UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_029_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_029_001&phenotyping_center=UC Davis microphthalmia Sptan1 heterozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_002_002 enlarged spleen Sptan1 heterozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_016_002 abnormal neural tube morphology Sptan1 homozygote male E9.5 Gross Morphology Embryo E9.5 Neural tube morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=UC Davis abnormal spleen morphology Sptan1 heterozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_016_002 abnormal craniofacial morphology Sptan1 homozygote male E15.5 Gross Morphology Embryo E14.5-E15.5 Craniofacial morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GEO_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEO_003¶meter_stable_id=IMPC_GEO_063_001&phenotyping_center=UC Davis abnormal placenta morphology Sptan1 heterozygote female E15.5 Gross Morphology Placenta E14.5-E15.5 Placenta Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_GPO_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GPO_001¶meter_stable_id=IMPC_GPO_002_001&phenotyping_center=UC Davis abnormal placenta morphology Sptan1 homozygote male E15.5 Gross Morphology Placenta E14.5-E15.5 Placenta Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=homozygote¶meter_stable_id=IMPC_GPO_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GPO_001¶meter_stable_id=IMPC_GPO_002_001&phenotyping_center=UC Davis abnormal kidney morphology Sptan1 heterozygote male Early adult Gross Pathology and Tissue Collection Kidney UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:98386/IMPC_PAT_017_002 decreased body length Sptan1 heterozygote female Early adult Body Composition (DEXA lean/fat) Body length UC Davis IMPC 3.57E-7 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_DXA_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_006_001&phenotyping_center=UC Davis persistence of hyaloid vascular system Sptan1 heterozygote not_considered Early adult Eye Morphology Persistence of hyaloid vascular system UC Davis IMPC 3.84E-7 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_027_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_027_001&phenotyping_center=UC Davis abnormal vitreous body morphology Sptan1 heterozygote not_considered Early adult Eye Morphology Vitreous UC Davis IMPC 4.77E-7 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_083_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_083_001&phenotyping_center=UC Davis cataract Sptan1 heterozygote not_considered Early adult Eye Morphology Lens Opacity UC Davis IMPC 8.45E-7 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_017_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_017_001&phenotyping_center=UC Davis abnormal retina vasculature morphology Sptan1 heterozygote male Early adult Eye Morphology Retinal Blood Vessels UC Davis IMPC 2.09E-5 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_024_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_024_001&phenotyping_center=UC Davis abnormal retina vasculature morphology Sptan1 heterozygote female Early adult Eye Morphology Retinal Blood Vessels UC Davis IMPC 9.92E-5 //www.mousephenotype.org/data/charts?accession=MGI:98386&allele_accession_id=MGI:6449035&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_024_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_024_001&phenotyping_center=UC Davis