Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Npr2 homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell abnormal forelimb morphology Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Forelimbs - size MRC Harwell IMPC 3.97E-13 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_019_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_019_001&phenotyping_center=MRC Harwell abnormal tail morphology Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Tail - thickness MRC Harwell IMPC 3.97E-13 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_003_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_003_001&phenotyping_center=MRC Harwell abnormal hindlimb morphology Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Hindlimbs - size MRC Harwell IMPC 3.97E-13 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_022_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_022_001&phenotyping_center=MRC Harwell abnormal head morphology Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Head morphology MRC Harwell IMPC 5.95E-12 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_026_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_026_001&phenotyping_center=MRC Harwell abnormal locomotor behavior Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Activity (body position) MRC Harwell IMPC 1.03E-10 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_029_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_029_001&phenotyping_center=MRC Harwell abnormal tail length Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Tail - length MRC Harwell IMPC 1.31E-10 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_002_001&phenotyping_center=MRC Harwell trunk curl Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Trunk curl MRC Harwell IMPC 1.18E-9 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_038_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_038_001&phenotyping_center=MRC Harwell limb grasping Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Limb grasp MRC Harwell IMPC 1.47E-9 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_039_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_039_001&phenotyping_center=MRC Harwell increased freezing behavior Npr2 homozygote female Early adult Fear Conditioning Conditioning Baseline % Freezing Time MRC Harwell IMPC 1.73E-9 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_FEA_003_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_FEA_001¶meter_stable_id=IMPC_FEA_003_001&phenotyping_center=MRC Harwell tremors Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Tremor MRC Harwell IMPC 9.76E-9 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_030_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_030_001&phenotyping_center=MRC Harwell abnormal tail morphology Npr2 heterozygote male Early adult Combined SHIRPA and Dysmorphology Tail - thickness MRC Harwell IMPC 1.51E-8 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_003_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_003_001&phenotyping_center=MRC Harwell abnormal head size Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Head size MRC Harwell IMPC 3.87E-8 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_025_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_025_001&phenotyping_center=MRC Harwell abnormal tail morphology Npr2 homozygote male Early adult Combined SHIRPA and Dysmorphology Tail - thickness MRC Harwell IMPC 2.53E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_003_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_003_001&phenotyping_center=MRC Harwell abnormal forelimb morphology Npr2 homozygote male Early adult Combined SHIRPA and Dysmorphology Forelimbs - size MRC Harwell IMPC 2.53E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_019_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_019_001&phenotyping_center=MRC Harwell abnormal hindlimb morphology Npr2 homozygote male Early adult Combined SHIRPA and Dysmorphology Hindlimbs - size MRC Harwell IMPC 2.53E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_022_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_022_001&phenotyping_center=MRC Harwell decreased circulating alkaline phosphatase level Npr2 homozygote female Early adult Clinical Chemistry Alkaline phosphatase MRC Harwell IMPC 3.74E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CBC_002¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=MRC Harwell abnormal snout morphology Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Snout size MRC Harwell IMPC 6.34E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_028_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_028_001&phenotyping_center=MRC Harwell abnormal gait Npr2 homozygote female Early adult Combined SHIRPA and Dysmorphology Gait MRC Harwell IMPC 9.2E-7 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_033_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_033_001&phenotyping_center=MRC Harwell abnormal tail length Npr2 homozygote male Early adult Combined SHIRPA and Dysmorphology Tail - length MRC Harwell IMPC 5.32E-6 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_CSD_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_002_001&phenotyping_center=MRC Harwell increased grip strength Npr2 heterozygote not_considered Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight MRC Harwell IMPC 7.41E-6 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=heterozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=MRC Harwell increased freezing behavior Npr2 homozygote female Early adult Fear Conditioning Cue Baseline % Freezing Time MRC Harwell IMPC 1.12E-5 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_FEA_015_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_FEA_001¶meter_stable_id=IMPC_FEA_015_001&phenotyping_center=MRC Harwell abnormal snout morphology Npr2 heterozygote male Early adult Combined SHIRPA and Dysmorphology Snout size MRC Harwell IMPC 2.01E-5 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_028_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_028_001&phenotyping_center=MRC Harwell impaired cued conditioning behavior Npr2 homozygote female Early adult Fear Conditioning Difference in Cue Tone and Cue Baseline % Freezing MRC Harwell IMPC 3.26E-5 //www.mousephenotype.org/data/charts?accession=MGI:97372&allele_accession_id=MGI:6276971&zygosity=homozygote¶meter_stable_id=IMPC_FEA_106_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_FEA_001¶meter_stable_id=IMPC_FEA_106_001&phenotyping_center=MRC Harwell