Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Mecom homozygote not_considered Early adult Viability Primary Screen Viability Outcome JAX IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:6361166&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=JAX increased startle reflex Mecom heterozygote male Early adult Acoustic Startle&PPI PP1 startle magnitude MRC Harwell EuroPhenome 4.55E-15 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_002&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_002&phenotyping_center=MRC Harwell increased total body fat amount Mecom heterozygote female Early adult DEXA Fat mass MRC Harwell EuroPhenome 1.28E-14 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_005_001_002&pipeline_stable_id=ESLIM_001&procedure_stable_id=ESLIM_005_001¶meter_stable_id=ESLIM_005_001_002&phenotyping_center=MRC Harwell decreased hemoglobin content Mecom heterozygote male Early adult Haematology Haemoglobin MRC Harwell EuroPhenome 1.61E-12 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_003&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_003&phenotyping_center=MRC Harwell increased startle reflex Mecom heterozygote male Early adult Acoustic Startle&PPI 110dB startle magnitude MRC Harwell EuroPhenome 1.61E-12 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_006&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_006&phenotyping_center=MRC Harwell increased total body fat amount Mecom heterozygote female Early adult DEXA Fat/Body weight MRC Harwell EuroPhenome 1.68E-12 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_005_001_703&pipeline_stable_id=ESLIM_001&procedure_stable_id=ESLIM_005_001¶meter_stable_id=ESLIM_005_001_703&phenotyping_center=MRC Harwell increased lean body mass Mecom heterozygote female Early adult DEXA Lean/Body weight MRC Harwell EuroPhenome 5.49E-10 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_005_001_702&pipeline_stable_id=ESLIM_001&procedure_stable_id=ESLIM_005_001¶meter_stable_id=ESLIM_005_001_702&phenotyping_center=MRC Harwell thrombocytopenia Mecom heterozygote male Early adult Hematology Platelet count JAX IMPC 8.56E-10 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:6361166&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_008_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_008_001&phenotyping_center=JAX increased startle reflex Mecom heterozygote female Early adult Acoustic Startle&PPI 110dB startle magnitude MRC Harwell EuroPhenome 3.08E-9 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_006&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_006&phenotyping_center=MRC Harwell decreased hemoglobin content Mecom heterozygote female Early adult Haematology Haemoglobin MRC Harwell EuroPhenome 6.66E-9 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_003&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_003&phenotyping_center=MRC Harwell increased startle reflex Mecom heterozygote female Early adult Acoustic Startle&PPI PP1 startle magnitude MRC Harwell EuroPhenome 1.74E-8 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_002&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_002&phenotyping_center=MRC Harwell decreased prepulse inhibition Mecom heterozygote female Early adult Acoustic Startle&PPI Prepulse inhibition - PP3 MRC Harwell EuroPhenome 1.85E-7 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_703&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_703&phenotyping_center=MRC Harwell decreased prepulse inhibition Mecom heterozygote female Early adult Acoustic Startle&PPI Prepulse inhibition - PP2 MRC Harwell EuroPhenome 1.92E-7 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_702&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_702&phenotyping_center=MRC Harwell decreased prepulse inhibition Mecom heterozygote female Early adult Acoustic Startle&PPI Global prepulse inhibition MRC Harwell EuroPhenome 3.04E-7 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_705&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_705&phenotyping_center=MRC Harwell abnormal startle reflex Mecom heterozygote male Early adult Modified SHIRPA Startle response MRC Harwell EuroPhenome 3.6E-7 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_008_001_013&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_008_001¶meter_stable_id=ESLIM_008_001_013&phenotyping_center=MRC Harwell increased bone mineral content Mecom heterozygote female Early adult DEXA Bone Mineral Content MRC Harwell EuroPhenome 6.88E-7 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_005_001_005&pipeline_stable_id=ESLIM_001&procedure_stable_id=ESLIM_005_001¶meter_stable_id=ESLIM_005_001_005&phenotyping_center=MRC Harwell thrombocytopenia Mecom heterozygote female Early adult Hematology Platelet count JAX IMPC 1.06E-6 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:6361166&zygosity=heterozygote¶meter_stable_id=IMPC_HEM_008_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_008_001&phenotyping_center=JAX increased circulating amylase level Mecom heterozygote male Early adult Clinical Chemistry Alpha-amylase MRC Harwell EuroPhenome 1.47E-6 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_015_001_016&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_015_001¶meter_stable_id=ESLIM_015_001_016&phenotyping_center=MRC Harwell decreased prepulse inhibition Mecom heterozygote female Early adult Acoustic Startle&PPI Prepulse inhibition - PP4 MRC Harwell EuroPhenome 1.91E-6 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_704&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_704&phenotyping_center=MRC Harwell decreased erythrocyte cell number Mecom heterozygote male Early adult Haematology Red blood cell count MRC Harwell EuroPhenome 7.77E-6 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_002&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_002&phenotyping_center=MRC Harwell abnormal locomotor activation Mecom heterozygote female Early adult Modified SHIRPA Body position MRC Harwell EuroPhenome 1.0E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_008_001_001&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_008_001¶meter_stable_id=ESLIM_008_001_001&phenotyping_center=MRC Harwell increased blood urea nitrogen level Mecom heterozygote male Early adult Clinical Chemistry Urea MRC Harwell EuroPhenome 1.69E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_015_001_002&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_015_001¶meter_stable_id=ESLIM_015_001_002&phenotyping_center=MRC Harwell decreased lean body mass Mecom heterozygote female Early adult DEXA Lean mass MRC Harwell EuroPhenome 1.77E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_005_001_003&pipeline_stable_id=ESLIM_001&procedure_stable_id=ESLIM_005_001¶meter_stable_id=ESLIM_005_001_003&phenotyping_center=MRC Harwell increased startle reflex Mecom heterozygote male Early adult Acoustic Startle&PPI PP4 startle magnitude MRC Harwell EuroPhenome 1.83E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_005&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_005&phenotyping_center=MRC Harwell decreased prepulse inhibition Mecom heterozygote male Early adult Acoustic Startle&PPI Prepulse inhibition - PP3 MRC Harwell EuroPhenome 1.84E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_011_001_703&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_011_001¶meter_stable_id=ESLIM_011_001_703&phenotyping_center=MRC Harwell limb grasping Mecom heterozygote male Early adult Modified SHIRPA Limb grasping MRC Harwell EuroPhenome 3.97E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_008_001_017&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_008_001¶meter_stable_id=ESLIM_008_001_017&phenotyping_center=MRC Harwell decreased hemoglobin content Mecom heterozygote male Early adult Haematology Mean cell haemoglobin concentration MRC Harwell EuroPhenome 5.39E-5 //www.mousephenotype.org/data/charts?accession=MGI:95457&allele_accession_id=MGI:2158381&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_007&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_007&phenotyping_center=MRC Harwell