Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data enlarged heart Cyp27a1 homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:88594/IMPC_PAT_006_002 abnormal heart morphology Cyp27a1 homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:88594/IMPC_PAT_006_002 increased circulating alkaline phosphatase level Cyp27a1 homozygote male Early adult Clinical Chemistry Alkaline phosphatase UC Davis IMPC 3.78E-18 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=UC Davis increased circulating alkaline phosphatase level Cyp27a1 homozygote female Early adult Clinical Chemistry Alkaline phosphatase UC Davis IMPC 5.63E-10 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=UC Davis increased liver weight Cyp27a1 homozygote male Early adult Organ Weight Liver weight UC Davis IMPC 2.68E-7 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=UCD_OWT_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=UCD_OWT_001¶meter_stable_id=UCD_OWT_008_001&phenotyping_center=UC Davis decreased circulating triglyceride level Cyp27a1 homozygote male Early adult Clinical Chemistry Triglycerides UC Davis IMPC 7.23E-6 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_017_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_017_001&phenotyping_center=UC Davis decreased circulating cholesterol level Cyp27a1 homozygote male Early adult Clinical Chemistry Total cholesterol UC Davis IMPC 8.63E-6 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_015_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_015_001&phenotyping_center=UC Davis shortened QRS complex duration Cyp27a1 homozygote female Early adult Electrocardiogram (ECG) QRS UC Davis IMPC 1.71E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_ECG_007_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_007_001&phenotyping_center=UC Davis decreased mean platelet volume Cyp27a1 homozygote not_considered Early adult Hematology Mean platelet volume UC Davis IMPC 1.9E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_HEM_019_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_019_001&phenotyping_center=UC Davis decreased heart rate Cyp27a1 homozygote not_considered Early adult Electrocardiogram (ECG) HR UC Davis IMPC 2.73E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_ECG_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_002_001&phenotyping_center=UC Davis decreased circulating HDL cholesterol level Cyp27a1 homozygote not_considered Early adult Clinical Chemistry HDL-cholesterol UC Davis IMPC 3.31E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_016_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_016_001&phenotyping_center=UC Davis prolonged RR interval Cyp27a1 homozygote not_considered Early adult Electrocardiogram (ECG) RR UC Davis IMPC 4.17E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_ECG_004_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_004_001&phenotyping_center=UC Davis improved glucose tolerance Cyp27a1 homozygote not_considered Early adult Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve UC Davis IMPC 7.41E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_IPG_012_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_012_001&phenotyping_center=UC Davis increased lean body mass Cyp27a1 homozygote not_considered Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 8.15E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased circulating serum albumin level Cyp27a1 homozygote male Early adult Clinical Chemistry Albumin UC Davis IMPC 9.85E-5 //www.mousephenotype.org/data/charts?accession=MGI:88594&allele_accession_id=MGI:5708271&zygosity=homozygote¶meter_stable_id=IMPC_CBC_007_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_007_001&phenotyping_center=UC Davis