Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Dtx4 homozygote female Early adult Viability Primary Screen Homozygous females viability CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=CCP-IMG preweaning lethality, complete penetrance Dtx4 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=CCP-IMG enlarged thymus Dtx4 heterozygote female Early adult Gross Pathology and Tissue Collection Thymus CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_004_002 abnormal thymus morphology Dtx4 heterozygote female Early adult Gross Pathology and Tissue Collection Thymus CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_004_002 abnormal thymus morphology Dtx4 heterozygote female Early adult Gross Pathology and Tissue Collection Thymus CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_004_002 enlarged heart Dtx4 heterozygote male Early adult Gross Pathology and Tissue Collection Heart CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_006_002 enlarged thymus Dtx4 heterozygote female Early adult Gross Pathology and Tissue Collection Thymus CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_004_002 abnormal heart morphology Dtx4 heterozygote male Early adult Gross Pathology and Tissue Collection Heart CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2672905/IMPC_PAT_006_002 no spontaneous movement Dtx4 homozygote no_data E18.5 Gross Morphology Embryo E18.5 Spontaneous movement CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=homozygote¶meter_stable_id=IMPC_GEP_004_002&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_004_002&phenotyping_center=CCP-IMG preweaning lethality, complete penetrance Dtx4 homozygote male Early adult Viability Primary Screen Homozygous males viability CCP-IMG IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=CCP-IMG increased circulating alkaline phosphatase level Dtx4 heterozygote female Early adult Clinical Chemistry Alkaline phosphatase CCP-IMG IMPC 9.82E-7 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=heterozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=CCP-IMG impaired glucose tolerance Dtx4 heterozygote female Early adult Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve CCP-IMG IMPC 7.86E-6 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=heterozygote¶meter_stable_id=IMPC_IPG_012_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_012_001&phenotyping_center=CCP-IMG increased airway resistance Dtx4 heterozygote male Early adult Lung mechanics by forced oscillations Rp8 CCP-IMG IMPC 4.97E-5 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=heterozygote¶meter_stable_id=CCP_LFO_008_001&pipeline_stable_id=CCP_001&procedure_stable_id=CCP_LFO_001¶meter_stable_id=CCP_LFO_008_001&phenotyping_center=CCP-IMG impaired glucose tolerance Dtx4 heterozygote female Early adult Intraperitoneal glucose tolerance test (IPGTT) Initial response to glucose challenge CCP-IMG IMPC 8.74E-5 //www.mousephenotype.org/data/charts?accession=MGI:2672905&allele_accession_id=MGI:6341925&zygosity=heterozygote¶meter_stable_id=IMPC_IPG_011_001&pipeline_stable_id=CCP_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_011_001&phenotyping_center=CCP-IMG